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1.发明公开ISOQUINOLINONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE ( COPD ) AND ASTHMA 有权ISOQUINOLINDERIVATE，其制造方法和它们在治疗哮喘和慢性阻塞性肺疾病的治疗
公开(公告)号：EP2144881A1
公开(公告)日：2010-01-20
申请号：EP08718978.3
申请日：2008-04-04
申请人： AstraZeneca AB
发明人： HALLAM, Matthew , MARTIN, Barrie , RAUBO, Piotr , ROBERTS, Bryan , ST-GALLAY, Stephen , WILLIS, Paul
IPC分类号： C07D217/24 , C07D401/06 , C07D401/10 , C07D401/12 , C07D401/14 , C07D487/08 , A61K31/4353 , A61P11/06
CPC分类号： C07D217/24 , C07D217/26 , C07D401/06 , C07D401/10 , C07D401/12 , C07D401/14 , C07D487/08
摘要： The present invention relates to isoquinolinone derivatives of formula (I): should be wherein R1, R2, R3, R4, R5, R6 and R7 are as herein defined; processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
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2.发明公开AMINE DERIVATIVES AND THEIR USE IN BETA-2-ADRENORECEPTOR MEDIATED DISEASES 审中-公开AMERDERIVATE UND IHRE VERWENDUNG BEI BETA-2-ADRENOREZEPTOR-VERMITTELTEN ERKRANKUNGEN
公开(公告)号：EP2094646A1
公开(公告)日：2009-09-02
申请号：EP07848596.8
申请日：2007-12-19
申请人： AstraZeneca AB
发明人： ALCARAZ, Lilian , BONNERT, Roger Victor , CONNOLLY, Stephen , COOK, Anthony, Ronald , FISHER, Adrian , HUMPHRIES, Alexander , RAUBO, Piotr
IPC分类号： C07C237/08 , C07C237/10 , C07D209/34 , C07D265/36 , C07D215/227 , A61K31/4704 , A61K31/536 , A61P11/00 , A61P29/00 , C07C233/01
CPC分类号： C07D265/36 , C07C233/43 , C07C2601/14 , C07D209/34 , C07D215/26 , C07D409/12 , C07D413/12
摘要： The present invention provides compounds of formula (I), wherein k, Ar, R2, R3, R4, R5, R4', R5', R6, R7, A, D, m and E are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
摘要翻译： 本发明提供式（I）化合物，其中k，Ar，R2，R3，R4，R5，R4'，R5'，R6，R7，A，D，m和E如说明书中所定义， 其制剂，含有它们的药物组合物及其在治疗中的用途。
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3.发明公开
公开(公告)号：EP2170848A1
公开(公告)日：2010-04-07
申请号：EP08776162.3
申请日：2008-06-25
申请人： AstraZeneca AB
IPC分类号： C07D241/20 , C07D401/12 , C07D403/04 , C07D403/12 , C07D413/12 , A61K31/454 , A61P11/06
CPC分类号： C07D491/113 , C07D241/08 , C07D241/20 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D413/04 , C07D413/12 , C07D471/10
摘要： The present invention relates to py razinone derivatives of formula (I) wherein R1, R2, R3, R4, R5, R6 and R7 are as herein defined; processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
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4.发明授权
公开(公告)号：EP2170848B1
公开(公告)日：2014-10-22
申请号：EP08776162.3
申请日：2008-06-25
申请人： AstraZeneca AB
IPC分类号： C07D241/20 , C07D401/12 , C07D403/04 , C07D403/12 , C07D413/12 , A61K31/454 , A61P11/06
CPC分类号： C07D491/113 , C07D241/08 , C07D241/20 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D413/04 , C07D413/12 , C07D471/10
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5.发明授权ISOQUINOLINONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE ( COPD ) AND ASTHMA 有权ISOQUINOLINDERIVATE，其制造方法和它们在治疗哮喘和慢性阻塞性肺疾病的治疗
公开(公告)号：EP2144881B1
公开(公告)日：2012-06-20
申请号：EP08718978.3
申请日：2008-04-04
申请人： AstraZeneca AB
发明人： HALLAM, Matthew , MARTIN, Barrie , RAUBO, Piotr , ROBERTS, Bryan , ST-GALLAY, Stephen , WILLIS, Paul
IPC分类号： C07D217/24 , C07D401/06 , C07D401/10 , C07D401/12 , C07D401/14 , C07D487/08 , A61K31/4353 , A61P11/06
CPC分类号： C07D217/24 , C07D217/26 , C07D401/06 , C07D401/10 , C07D401/12 , C07D401/14 , C07D487/08
摘要： The present invention relates to isoquinolinone derivatives of formula (I): should be wherein R1, R2, R3, R4, R5, R6 and R7 are as herein defined; processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
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6.发明公开BENZOXAZINONE DERIVATIVES ACTING AS BETA2-ADRENORECEPTOR AGONIST FOR THE TREATMENT OF RESPIRATORY DISORDERS 审中-公开BENZOXAZINONDERIVATE ALS BETA2肾上腺素能受体激动剂治疗呼吸道疾病
公开(公告)号：EP2303873A1
公开(公告)日：2011-04-06
申请号：EP09766947.7
申请日：2009-06-17
申请人： AstraZeneca AB
发明人： BONNERT, Roger, Victor , CONNOLLY, Stephen , COOK, Anthony Ronald , EVANS, Richard , RAUBO, Piotr
IPC分类号： C07D413/12 , A61K31/538 , A61P11/00 , C07D231/12
CPC分类号： C07D231/12 , A61K31/538 , A61K45/06 , C07D413/12
摘要： The present invention provides a compound of formula (I), wherein W, R
1 , R
2 and R
3 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
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