-
1.发明授权VERWENDUNG VON INHIBITOREN DES ZELLULÄREN Na+ /H+ -EXCHANGERS (NHE) ZUR HERSTELLUNG EINES MEDIKAMENTS ZUR NORMALISIERUNG DER SERUMLIPIDE 失效作者细胞Na + / H + -EXCHANGERS（NHE）抑制剂用于生产一种药物，用于归一化血清脂质USE
公开(公告)号：EP0918515B1
公开(公告)日：2005-04-27
申请号：EP97923937.3
申请日：1997-05-20
发明人： LANG, Hans, Jochen , JANSEN, Hans-Willi , SCHWARK, Jan-Robert , KLEEMANN, Heinz-Werner , JUNG, Oliver , SCHÄFER, Hans-Ludwig , LINZ, Wolfgang , KRAMER, Werner , SCHÖLKENS, Bernward , FALK, Eugen
IPC分类号： A61K31/155 , A61K31/455 , A61K31/22 , A61K45/00 , A61K45/06 , A61P3/06
CPC分类号： A61K31/166 , A61K31/00 , A61K31/155 , A61K31/22 , A61K31/365 , A61K31/165 , A61K2300/00
摘要： The active substances identified as inhibitors of the cellular Na+/H+ exchanger (NHE) are used to prepare a medicament for normalizing serum lipids. They are used in the preparation of a medicament which reduces lipid levels in the blood and can be administered for treating diseases caused by lipid levels which are too high, and for alleviating the endothelial dysfunctional syndrome and for treating diseases caused thereby.
-
2.发明授权ARYLSUBSTITUIERTE PROPANOLAMINDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG, DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL UND DEREN VERWENDUNG 有权芳基取代的丙醇胺，METHOD FOR THEIR，药物含有它们的及其用途
公开(公告)号：EP1117645B1
公开(公告)日：2004-05-06
申请号：EP99970083.4
申请日：1999-09-18
IPC分类号： C07D213/74 , A61K31/44
CPC分类号： C07H15/18
摘要： The invention relates to aryl-substituted propanolamine derivatives and their pharmaceutically acceptable salts and functional derivatives. The invention relates to compounds of formula (I), wherein the radicals have the defined meanings, to their physiologically acceptable salts, physiologically functional derivatives and to methods for their production. The compounds are suitable as, e.g. hypolipidemic agents.
-
3.发明授权MIT ZUCKERRESTEN SUBSTITUIERTE 1,4-BENZOTHIAZEPIN-1,1-DIOXIDDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG, DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL UND DEREN VERWENDUNG 有权用糖仍然是取代的1,4-苯并硫氮杂-1,1-二氧化物的衍生物，用于生产药物含有它们及其用途
公开(公告)号：EP1169313B1
公开(公告)日：2003-06-25
申请号：EP00920550.1
申请日：2000-03-23
IPC分类号： C07D281/00
CPC分类号： C07D281/10 , A61K31/554 , Y02P20/55
摘要： The invention relates to substituted 1,4-benzothiazepine-1,1-dioxide derivatives and to the acid addition salts thereof. The invention discloses 1,4-benzothiazepine-1,1-dioxide derivatives of formula (I), wherein R?1, R2, R3¿ and Z have the cited descriptions, the physiologically compatible salts thereof and physiologically functional derivatives, as well as methods for producing the same. The compounds are suited for use, e.g. as hypolipidemic agents.
-
4.发明公开ARYLSUBSTITUIERTE PROPANOLAMINDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG, DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL UND DEREN VERWENDUNG 有权芳基取代的丙醇胺，METHOD FOR THEIR，药物含有它们的及其用途
公开(公告)号：EP1117645A1
公开(公告)日：2001-07-25
申请号：EP99970083.4
申请日：1999-09-18
IPC分类号： C07D213/74 , A61K31/44
CPC分类号： C07H15/18
摘要： The invention relates to aryl-substituted propanolamine derivatives and their pharmaceutically acceptable salts and functional derivatives. The invention relates to compounds of formula (I), wherein the radicals have the defined meanings, to their physiologically acceptable salts, physiologically functional derivatives and to methods for their production. The compounds are suitable as, e.g. hypolipidemic agents.
-
5.发明公开MIT ZUCKERRESTEN SUBSTITUIERTE 1,4-BENZOTHIAZEPIN-1,1-DIOXIDDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG, DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL UND DEREN VERWENDUNG 有权用糖仍然是取代的1,4-苯并硫氮杂-1,1-二氧化物的衍生物，用于生产药物含有它们及其用途
公开(公告)号：EP1169313A2
公开(公告)日：2002-01-09
申请号：EP00920550.1
申请日：2000-03-23
IPC分类号： C07D281/00
CPC分类号： C07D281/10 , A61K31/554 , Y02P20/55
摘要： The invention relates to substituted 1,4-benzothiazepine-1,1-dioxide derivatives and to the acid addition salts thereof. The invention discloses 1,4-benzothiazepine-1,1-dioxide derivatives of formula (I), wherein R?1, R2, R3¿ and Z have the cited descriptions, the physiologically compatible salts thereof and physiologically functional derivatives, as well as methods for producing the same. The compounds are suited for use, e.g. as hypolipidemic agents.
-
-
-
-
搜索结果
5 条记录 (耗时 0.014 秒)
