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1.发明公开NEUE CYTOCHROM P450-MONOOXYGENASEN UND DEREN VERWENDUNG ZUR OXIDATION VON ORGANISCHEN VERBINDUNGEN 有权新的细胞色素P450单加氧酶及其用于氧化有机化合物
公开(公告)号：EP1196605A1
公开(公告)日：2002-04-17
申请号：EP00956319.8
申请日：2000-07-27
发明人： HAUER, Bernhard , PLEISS, Juergen , SCHWANEBERG, Ulrich , SCHMITT, Jutta , FISCHER, Markus , SCHMID, Rolf , LI, Qing-shan , APPEL, Daniel
IPC分类号： C12N15/53 , C12N9/02 , C12N15/70 , C12N1/21 , C12P17/10 , C12P17/16 , C12P7/04 , C12P7/22 , C12P7/02
CPC分类号： C12N9/0071 , C12P7/02 , C12P7/04 , C12P7/22 , C12P7/6409 , C12P17/10 , C12P17/165 , C12Q1/26 , G01N2333/90245
摘要： The invention relates to novel cytochrome P450 monooxygenases comprising a modified substrate specificity, to nucleotide sequences which code therefor, to expression constructs and vectors containing these sequences, and to microorganisms transformed therewith. The invention also relates to methods for microbiologically oxidizing different organic substrates, such as methods for producing indigo and indirubin.
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公开(公告)号：EP1196603B1
公开(公告)日：2007-08-22
申请号：EP00951461.3
申请日：2000-07-27
发明人： HAUER, Bernhard , PLEISS, Juergen , SCHWANEBERG, Ulrich , SCHMITT, Jutta , FISCHER, Markus , SCHMID, Rolf , LI, Qing-shan
CPC分类号： C12P7/6409 , C12N9/0071 , C12N9/0077 , C12P7/02 , C12P7/04 , C12P7/22 , C12P7/42 , C12P17/10 , C12P17/165 , C12Q1/26 , G01N2333/90245
摘要： The invention relates to modified cytochrome P450 monooxygenases comprising a modified substrate profile, to nucleic acid sequences that code therefor, to expression constructs and vectors, and to recombinant microorganisms which contain these vectors. The invention also relates to methods for microbiologically producing terminally or subterminally hydroxylated aliphatic carboxylic acids.
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公开(公告)号：EP1196603A2
公开(公告)日：2002-04-17
申请号：EP00951461.3
申请日：2000-07-27
发明人： HAUER, Bernhard , PLEISS, Juergen , SCHWANEBERG, Ulrich , SCHMITT, Jutta , FISCHER, Markus , SCHMID, Rolf , LI, Qing-shan
CPC分类号： C12P7/6409 , C12N9/0071 , C12N9/0077 , C12P7/02 , C12P7/04 , C12P7/22 , C12P7/42 , C12P17/10 , C12P17/165 , C12Q1/26 , G01N2333/90245
摘要： The invention relates to modified cytochrome P450 monooxygenases comprising a modified substrate profile, to nucleic acid sequences that code therefor, to expression constructs and vectors, and to recombinant microorganisms which contain these vectors. The invention also relates to methods for microbiologically producing terminally or subterminally hydroxylated aliphatic carboxylic acids.
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