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1.发明公开MULTICOMPONENT CRYSTALLINE SYSTEM COMPRISING DEFERASIROX AND ISONICOTINAMIDE AND A PROCESS FOR THE PREPARATION THEREOF 有权结晶多组分系统和拉罗司ISONIKOTINAMID及其制造方法
公开(公告)号：EP2880019A1
公开(公告)日：2015-06-10
申请号：EP13750525.1
申请日：2013-08-05
Applicant: BASF SE
Inventor： HAFNER, Andreas , BLATTER, Fritz , RÖDEL, Eva , SZELAGIEWICZ, Martin , CHIODO, Tiziana , HINTERMANN, Tobias , SALVADOR, Beate , VOSSEN, Marcus
IPC: C07D249/08 , A61K31/4196 , A61P7/00
CPC classification number: C07D213/81 , C07B2200/13 , C07D249/08
Abstract: The present invention refers to a multicomponent crystalline system (co-crystal) comprising a compound of formula (1) (4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid; INN:Deferasirox) formula (1) and a compound of formula (2) (Isonicotinamide; pyridine-4-carboxamide) formula (2), as well as to a process for obtaining the same.
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2.发明授权MULTICOMPONENT CRYSTALLINE SYSTEM COMPRISING DEFERASIROX AND ISONICOTINAMIDE AND A PROCESS FOR THE PREPARATION THEREOF 有权结晶多组分系统和拉罗司ISONIKOTINAMID及其制造方法
公开(公告)号：EP2880019B1
公开(公告)日：2016-07-13
申请号：EP13750525.1
申请日：2013-08-05
Applicant: BASF SE
Inventor： HAFNER, Andreas , BLATTER, Fritz , RÖDEL, Eva , SZELAGIEWICZ, Martin , CHIODO, Tiziana , HINTERMANN, Tobias , SALVADOR, Beate , VOSSEN, Marcus
IPC: C07D213/81 , C07D249/08 , A61K31/4196 , A61P7/00
CPC classification number: C07D213/81 , C07B2200/13 , C07D249/08
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