VERFAHREN ZUR HERSTELLUNG VON 2'-O-FUCOSYLLACTOSE

    公开(公告)号:EP3411379A1

    公开(公告)日:2018-12-12

    申请号:EP17703388.3

    申请日:2017-02-02

    Applicant: BASF SE

    Abstract: The present invention relates to a process for producing 2'-O-fucosyllactose, to the intermediates obtainable by this process and to the use of these intermediates. Production comprises the reaction of a protected fucose of general formula (I) with a tri-(C
    1 -C
    6 -alkyl)silyl iodide to form a protected 1-iodofucose followed by reaction of the protected 1-iodofucose with a compound of general formula (I I), in the presence of at least one base and deprotection of the obtained coupling product to obtain 2'-O-fucosyllactose. The variables are defined as follows: R
    a and R
    b are identical or different and represent -C(=O)-C
    1 -C
    6 -alkyl or -C(=O)-phenyl, wherein phenyl is unsubstituted or optionally comprises 1 to 5 substituents or R
    a and R
    b together represent a -(C=O)- radical or a substituted methylene radical -C(R
    d R
    e )-, R
    c represents an R
    Si radical or benzyl, wherein benzyl is unsubstituted or optionally bears 1, 2 or 3 substituents, R
    Si represents a radical of formula SiR
    f R
    g R
    h , wherein R
    f , R
    g and R
    h are identical or different and represent, for example C
    1 -C
    8 -alkyl, R
    1 represents a -C(=O)-R
    11 radical or a SiR
    12 R
    13 R
    14 radical, R
    2 are identical or different and represent for example C
    1 -C
    8 -alkyl, R
    3 are identical or different and represent for example C
    1 -C
    8 -alkyl or both radicals R
    3 together represent linear C
    1 -C
    4 -alkenyl which is unsubstituted or bears 1 to 6 methyl groups as substituents.

    MODULARE KATALYSATORMONOLITHE
    3.
    发明公开

    公开(公告)号:EP3380222A1

    公开(公告)日:2018-10-03

    申请号:EP16802003.0

    申请日:2016-11-18

    Applicant: BASF SE

    CPC classification number: C01B21/28 B01J10/007 B01J19/2485 C01B21/26 C01B21/38

    Abstract: The invention relates to a reactor (R) with a device (D) containing a gas and/or liquid-permeable base (B) in whose edge region a lateral boundary (W) is arranged which entirely surrounds the base (B) and forms a volume (V), said volume containing catalytic and/or non-catalytic moulded bodies (F), wherein at least one mesh made of noble metal and/or non-noble metal is located on the side opposing the base (B) in the upstream direction, and the catalytic and/or non-catalytic moulded bodies (F) are selected from (i) moulded bodies (F1) in the form of straight prisms whose base surface is selected from a triangle, rectangle, hexagon or fragments of these polygons, or (ii) a combination of the moulded bodies (F1) with moulded bodies (F2) that are smaller than the moulded bodies (F1), characterised in that groups of m to n moulded bodies (F1), where m/n is a whole number between 3-30 and n > m, are bound to form modules (M) in a metal cassette that is open upstream and closed with a gas-permeable base in the downstream direction, with their lateral surfaces side by side practically without a gap and with their longitudinal axis oriented in the vertical direction, such that the cross-section of the base is practically entirely covered, and which modules (M) are joined to one another in a mosaic-like manner practically without a gap, with the vertical orientation of the longitudinal axis of the moulded bodies (F1), optionally with the cooperation of a joint filling material.

    REAKTOR UND VERFAHREN ZUR HERSTELLUNG VON SCHWEFELWASSERSTOFF
    4.
    发明授权
    REAKTOR UND VERFAHREN ZUR HERSTELLUNG VON SCHWEFELWASSERSTOFF 有权
    反应器和方法氢气的生产

    公开(公告)号:EP2125612B1

    公开(公告)日:2011-03-30

    申请号:EP08701458.5

    申请日:2008-01-14

    Applicant: BASF SE

    Abstract: The invention relates to a reactor (1) and a method for continuously producing H2S by reacting a feedstock mixture essentially containing gaseous sulfur and hydrogen on a catalyst. The reactor (1) comprises a sulfur melt (9), at least in a bottom subarea (8) of the reactor (1) into which gaseous hydrogen is introduced. The catalyst is arranged in at least one U-shaped tube (21) that is in partial contact with the sulfur melt (9). The at least one U-shaped tube (21) has at least one inlet (23) on a leg (26) above the sulfur melt (9), the feedstock mixture being able to penetrate from a feedstock zone (10) of the reactor (1) into the U-shaped tube (21) through said inlet (23). The at least one U-shaped tube (21) also has an internal flow path, along which the feedstock mixture can be reacted in a reaction zone containing the catalyst (22), and at least one outlet (24) in another leg (27), a product being able to be discharged into a product zone (7) through said outlet (24).

    REAKTOR UND VERFAHREN ZUR HERSTELLUNG VON SCHWEFELWASSERSTOFF
    9.
    发明公开
    REAKTOR UND VERFAHREN ZUR HERSTELLUNG VON SCHWEFELWASSERSTOFF 有权
    反应器和方法氢气的生产

    公开(公告)号:EP2125612A1

    公开(公告)日:2009-12-02

    申请号:EP08701458.5

    申请日:2008-01-14

    Applicant: BASF SE

    Abstract: The invention relates to a reactor (1) and a method for continuously producing H2S by reacting a feedstock mixture essentially containing gaseous sulfur and hydrogen on a catalyst. The reactor (1) comprises a sulfur melt (9), at least in a bottom subarea (8) of the reactor (1) into which gaseous hydrogen is introduced. The catalyst is arranged in at least one U-shaped tube (21) that is in partial contact with the sulfur melt (9). The at least one U-shaped tube (21) has at least one inlet (23) on a leg (26) above the sulfur melt (9), the feedstock mixture being able to penetrate from a feedstock zone (10) of the reactor (1) into the U-shaped tube (21) through said inlet (23). The at least one U-shaped tube (21) also has an internal flow path, along which the feedstock mixture can be reacted in a reaction zone containing the catalyst (22), and at least one outlet (24) in another leg (27), a product being able to be discharged into a product zone (7) through said outlet (24).

Patent Agency Ranking