公开(公告)号：EP3714959A1

公开(公告)日：2020-09-30

申请号：EP19166238.6

申请日：2019-03-29

Applicant: BASF SE

Inventor： WEINGARTEN, Melanie ,  IFFLAND, Gabriele ,  SA GOMES, Pedro ,  PUHL, Michael ,  SIEGEL, Wolfgang ,  GARELLA, Linda ,  COOPER, Bryan ,  MUELLER, Patric ,  ZELDER; Oskar ,  SCHRÖDER, Hartwig

IPC: B01D15/08 ,  B01D15/36 ,  C12P15/00 ,  C12P17/18 ,  C12R1/645 ,  A01N43/56 ,  A01N37/42

Abstract: The present invention relates to an improved process for isolating aliphatic, mono- or polycyclic small molecules, in particular, Cycloclavine or Cornexistin and/or Hydroxycornexistin, from the aqueous fermentation broth of a eukaryotic microorganism. Said process comprises contacting a liquid phase of said fermentation broth containing said active ingredient with a suitable adsorbent, desorbing said active ingredient from said adsorbent, optionally performing a second chromatographic purification step, and isolating the active ingredient in substantially pure form. The thus obtained purified small molecules may be further used in biocidal, i.p. insecticidal or herbicidal compositions.