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公开(公告)号：EP1796744B1
公开(公告)日：2008-11-05
申请号：EP05790849.3
申请日：2005-08-17
CPC分类号： C11D3/48 , A61L12/141 , A61L12/142 , A61L12/143 , A61L12/145 , C11D1/722 , C11D3/0078 , C11D3/30 , C11D3/323 , C11D3/3703 , C11D3/3723 , C11D3/3726
摘要： The use of compositions containing one or more antimicrobial agents with one or more trialkanolamine alkoxylate buffers to disinfect and/or preserve medical devices is described. Solutions containing one or more antimicrobial agents with one or more trialkanolamine alkoxylate buffers and methods of making and using the same are also described.
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公开(公告)号：EP1080138B1
公开(公告)日：2002-08-28
申请号：EP99918751.1
申请日：1999-04-21
CPC分类号： C08J7/123 , B29D11/00192 , B82Y15/00 , C08J2343/04 , C08J2383/04 , G02B1/043
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公开(公告)号：EP1080138A1
公开(公告)日：2001-03-07
申请号：EP99918751.1
申请日：1999-04-21
CPC分类号： C08J7/123 , B29D11/00192 , B82Y15/00 , C08J2343/04 , C08J2383/04 , G02B1/043
摘要： The present invention provides an optically clear, hydrophilic coating upon the surface of a silicone hydrogel lens by subjecting the surface of the lens to a process comprising plasma treatment, hydration, and heat sterilization that is controlled to result in a silicate-containing film having a mosaic pattern of projecting plates surrounded by fissures when viewing a 50x50 micron square AFM image, wherein the peak-to-valley distances of the fissures are on average between about 100 and 500 angströms and the plate coverage is on average between about 40 % to 99 %.
摘要翻译： 本发明通过对透镜表面进行包括等离子体处理，水合和加热消毒的方法在硅酮水凝胶透镜表面上提供光学透明的亲水性涂层，所述方法被控制以导致含硅酸盐膜具有 当观察50×50微米的正方形AFM图像时，由裂隙环绕的投影板的马赛克图案，其中裂缝的峰谷距平均在约100和500埃之间，平板覆盖平均在约40％至99之间 ％。
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4.发明授权POLYMERIZABLE SURFACTANTS AND THEIR USE AS DEVICE FORMING COMONOMERS 有权聚合表面活性剂及其作为COMONOMERBILDENDE DEVICE
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5.发明公开
公开(公告)号：EP1706473A1
公开(公告)日：2006-10-04
申请号：EP04811763.4
申请日：2004-11-22
IPC分类号： C11D3/00
摘要： Compositions and methods for cleaning contact lenses employing one or more nonionic polyether surfactants having a HLB of less than 12 in an amount effective to reduce the amount of lipids on the contact lenses, thus rendering the contact lenses easier to clean. Additionally, by soaking contact lenses in the composition prior to inserting the lens on the eye, the compositions provide a prophylactic effect in preventing lipid deposition while the contact lens is worn.
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6.发明公开SURFACE TREATMENT OF SILICONE HYDROGEL CONTACT LENSES COMPRISING HYDROPHILIC POLYMER CHAINS ATTACHED TO AN INTERMEDIATE CARBON COATING 有权硅酮水凝胶隐形眼镜与打开之间的涂层的碳表面处理结合的亲水性聚合物
公开(公告)号：EP1187873A1
公开(公告)日：2002-03-20
申请号：EP00932520.0
申请日：2000-05-16
发明人： VALINT, Paul, L., Jr. , AMMON, Daniel, M., Jr. , MCGEE, Joseph, A. , GROBE, George, L. , OZARK, Richard, M.
CPC分类号： C08J7/045 , B29D11/00192 , C08J2383/04 , G02B1/043 , Y10T428/249921 , Y10T428/31504 , Y10T428/31536 , Y10T428/3154 , Y10T428/31663 , C08L83/10
摘要： The present invention provides an optically clear, hydrophilic coating upon the surface of a silicone medical device by sequentially subjecting the surface of the lens to plasma polymerization in a hydrocarbon-containing atmosphere and then covalently attaching a preformed hydrophilic polymer to the surface of the carbon coating. The invention is especially useful for forming a biocompatible coating on a silicone contact lens.
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7.发明公开PLASMA SURFACE TREATMENT OF SILICONE HYDROGEL CONTACT LENSES WITH A FLEXIBLE CARBON COATING 有权硅水凝胶隐形眼镜由等离子体手段和灵活的碳涂层表面处理
公开(公告)号：EP1187871A1
公开(公告)日：2002-03-20
申请号：EP00930624.2
申请日：2000-05-12
CPC分类号： C08J7/06 , C08J7/123 , C08J2383/04 , G02B1/043
摘要： The present invention is directed to the surface treatment of silicone hydrogel contact lenses. In particular, the present invention is directed to a method of modifying the surface of a contact lens to increase its hydrophilicity by coating the lens with a carbon-containing layer made from a diolefinic compound having 4 to 8 carbon atoms. In one embodiment, an optically clear, hydrophilic coating is provided upon the surface of a silicone hydrogel lens by sequentially subjecting the surface of the lens to: a plasma oxidation reaction, followed by a plasma polymerization reaction in the presence of a diolefin in the absence of air. Finally, the resulting carbon layer is rendered hydrophilic by a further plasma oxidation reaction or by the attachment of a hydrophilic polymer chain.
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8.发明公开COMPOSITIONS CONTAINING N,N,N',N'-TETRAKIS(HYDROXYALKYL)DIAMINE- OR N,N,N',N'-TETRAKIS(HYDROXYALKOXY) DIAMINE-BASED BUFFERS 审中-公开BUFFERS ON N，N，N 'N'-四（羟烷基）乙二胺或N，N，N'，N'-四（羟基烷氧基）二胺 - BASIS的组合物
公开(公告)号：EP1812085A1
公开(公告)日：2007-08-01
申请号：EP05786704.6
申请日：2005-08-17
CPC分类号： C11D7/3218 , A01N33/08 , A61L12/141 , A61L12/142 , A61L12/143 , A61L12/145 , C11D3/0078 , A01N47/44 , A01N33/12 , A01N2300/00
摘要： The use of compositions containing one or more antimicrobial agents with one or more (hydroxyalkyl)diamine-based buffers, (hydroxyalkoxy)diamine-based buffers or combinations thereof to disinfect and/or preserve medical devices is described. Solutions containing one or more antimicrobial agents with one or more (hydroxyalkyl)diamine-based buffers, (hydroxyalkoxy)diamine-based buffers or combinations thereof and methods of making and using the same are also described.
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9.发明授权COMPOSITIONS WITH ENHANCED ANTIMICROBIAL EFFICACY AGAINST ACANTHAMOEBAE 有权具有改进的抗微生物功效AGAINST Acanthamoebae组合物
公开(公告)号：EP1545635B1
公开(公告)日：2007-08-01
申请号：EP03759495.9
申请日：2003-09-22
发明人： BORAZJANI, Roya , XIA, Erning , AMMON, Daniel, M., Jr. , SALAMONE, Joseph, C. , HU, Zhenze , DOBIE, Alyce, K.
CPC分类号： C11D3/0078 , A01N33/12 , A01N43/16 , A61L12/14 , A61L12/141 , C11D3/227
摘要： Ophthalmic compositions such as eye drop and contact lens treating solutions include a polycationic material to enhance antimicrobial efficacy against protozoans such as acanthamoebae. One preferred class of polycationic materials is cationic cellulose derivatives.
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10.发明公开
公开(公告)号：EP1570038A1
公开(公告)日：2005-09-07
申请号：EP03790155.0
申请日：2003-12-01
发明人： JANI, Dharmendra , SALAMONE, Joseph, C. , ZHENZE, Hu , XIA, Erning , BORAZANI, Roya , AMMON, Daniel, M., Jr.
CPC分类号： C11D1/008 , C11D3/0078 , C11D3/3707 , G02B1/043
摘要： The present invention is directed to an ophthalmic solution for soft contact lenses for controlled release of polyethers into an eye's tear film. Polyether components of the subject ophthalmic solution are released from the soft contact lens material matrix over long time periods to produce longer lasting wetting performance, improved lubricity, improved end-of-the-day comfort and reduced feeling of dryness from wearing contact lenses.
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