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1.发明公开
公开(公告)号：EP1706473A1
公开(公告)日：2006-10-04
申请号：EP04811763.4
申请日：2004-11-22
IPC分类号： C11D3/00
摘要： Compositions and methods for cleaning contact lenses employing one or more nonionic polyether surfactants having a HLB of less than 12 in an amount effective to reduce the amount of lipids on the contact lenses, thus rendering the contact lenses easier to clean. Additionally, by soaking contact lenses in the composition prior to inserting the lens on the eye, the compositions provide a prophylactic effect in preventing lipid deposition while the contact lens is worn.
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公开(公告)号：EP1278818B1
公开(公告)日：2006-02-22
申请号：EP01928339.9
申请日：2001-03-30
CPC分类号： C11D3/227 , A61K9/0048 , A61L12/08 , C11D3/0078
摘要： A method for wetting a contact lens comprising administering an aqueous wetting solution comprising 0.001 to 10.0 percent by weight of a cationic cellulosic polymer provided that the solution has an ionic strength of less than about 0.10.
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3.发明公开ANTIMICROBIAL COMPOSITIONS CONTAINING ETHANOLAMINE BUFFER AND BIGUANIDE DISINFECTANT 有权抗微生物组合物乙醇胺缓冲液和双胍含消毒剂
公开(公告)号：EP1603396A2
公开(公告)日：2005-12-14
申请号：EP04757816.6
申请日：2004-03-18
发明人： HU, Zhenze , SALAMONE, Joseph, C.
摘要： The use of a composition of one or more aminoalcohol buffers in combination with one or more antimicrobial agents to disinfect contact lenses and preserve ophthalmic lens compositions is described. Ophthalmic lens solutions containing compositions of one or more aminoalcohol buffers in combination with one or more antimicrobial agents and methods of making and using the same are also described.
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4.发明公开Compositions and methods for treating, controlling, reducing, or ameliorating infections and sequelae thereof 有权感染的治疗及其与分离糖皮质激素受体激动剂和抗感染Mittlen的组合后遗症
公开(公告)号：EP2364707A2
公开(公告)日：2011-09-14
申请号：EP11169315.6
申请日：2007-08-01
发明人： HU, Zhenze , WARD, Keith Wayne , PHILLIPS, Gary , KERPPOLA, Raili
IPC分类号： A61K31/4725 , A61K45/06 , A61P27/00 , A61P31/00 , A61P31/04 , A61P33/00 , A61K31/4709
CPC分类号： A61K45/06 , A61K31/4709 , A61K31/4725 , A61K2300/00
摘要： A composition for treating, controlling, reducing, ameliorating, or alleviating infections and their inflammatory sequelae comprises a dissociated glucocorticoid receptor agonist ('DIGRA') and an anti-infective agent, such as an antibacterial, antiviral, antifungal, antiprotozoal agent, or a combination thereof. The composition can be formulated for topical application, injection, or implantation.
摘要翻译： 一种用于治疗，控制，减少，改善，或减轻感染及其炎性后遗症组合物包含分离的糖皮质激素受体激动剂（“DIGRA”）和抗感染剂的，：如抗菌，抗病毒，抗真菌，抗原生动物剂，或 它们的组合。 该组合物可以被配制成用于局部施用，注射，或植入。
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公开(公告)号：EP1687037A1
公开(公告)日：2006-08-09
申请号：EP04812430.9
申请日：2004-11-29
发明人： XIA, Erning , HU, Zhenze
CPC分类号： C11D3/227 , A01N43/16 , A61L12/08 , A61L12/145 , C11D3/221 , C11D3/222 , A01N2300/00
摘要： Compositions are described which are useful in preserving any topically applied solution. Compositions including one or more saccharides in combination with one or more cationic polysaccharides in solution in an amount effective to preserve contact lenses are also described, as well as methods of making and using such solutions.
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公开(公告)号：EP1458420A2
公开(公告)日：2004-09-22
申请号：EP02805567.1
申请日：2002-12-10
发明人： HU, Zhenze , LEVER, Andrea , SIMPSON, Lisa, C.
CPC分类号： A61L12/14 , A61K9/0051 , A61L12/08 , A61L12/141 , A61L12/143 , C11D1/008 , C11D3/0078 , C11D3/30 , C11D7/3218
摘要： A method for cleaning contact lenses employs a composition that includes tromethamine in an amount effective to reduce the amount of denatured protein on the contact lens, thus rendering the contact lenses easier to clean. Additionally, by soaking contact lenses in the composition prior to inserting the lens on the eye, the compositions provide a prophylactic effect in preventing protein denaturation while the contact lens is worn.
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7.发明授权TREATING INFECTIONS AND SEQUELAE THEREOF WITH COMBINED DISSOCIATED GLUCOCORTICOID RECEPTOR AGONISTS AND ANTI-INFECTIVE AGENTS 有权感染及其影响通过联合苦难处理分离GLOCUCORTICOID受体激动剂和抗感染剂
公开(公告)号：EP2049112B1
公开(公告)日：2012-03-14
申请号：EP07813634.8
申请日：2007-08-01
CPC分类号： A61K45/06 , A61K31/4709 , A61K31/4725 , A61K2300/00
摘要： A composition for treating, controlling, reducing, ameliorating, or alleviating infections and their inflammatory sequelae comprises a dissociated glucocorticoid receptor agonist ('DIGRA') and an anti-infective agent, such as an antibacterial, antiviral, antifungal, antiprotozoal agent, or a combination thereof. The composition can be formulated for topical application, injection, or implantation.
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8.发明公开COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST AND AN IMMUNOSUPPRESSIVE AGENT FOR TREATING DRY EYE 审中-公开用糖皮质激素游离受体激动剂和治疗干眼病的免疫成分
公开(公告)号：EP2051736A2
公开(公告)日：2009-04-29
申请号：EP07784492.6
申请日：2007-06-20
发明人： XIA, Erning , HU, Zhenze
CPC分类号： A61K45/06 , A61K38/13 , A61K2300/00
摘要： A composition for treating or reducing a dry eye condition or an ophthalmological disorder that has an etiology in inflammation comprises a dissociated glucocorticoid receptor agonist ('DIGRA'). The composition can be formulated for topical application, injection, or implantation.
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9.发明授权COMPOSITIONS WITH ENHANCED ANTIMICROBIAL EFFICACY AGAINST ACANTHAMOEBAE 有权具有改进的抗微生物功效AGAINST Acanthamoebae组合物
公开(公告)号：EP1545635B1
公开(公告)日：2007-08-01
申请号：EP03759495.9
申请日：2003-09-22
发明人： BORAZJANI, Roya , XIA, Erning , AMMON, Daniel, M., Jr. , SALAMONE, Joseph, C. , HU, Zhenze , DOBIE, Alyce, K.
CPC分类号： C11D3/0078 , A01N33/12 , A01N43/16 , A61L12/14 , A61L12/141 , C11D3/227
摘要： Ophthalmic compositions such as eye drop and contact lens treating solutions include a polycationic material to enhance antimicrobial efficacy against protozoans such as acanthamoebae. One preferred class of polycationic materials is cationic cellulose derivatives.
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公开(公告)号：EP1587553A1
公开(公告)日：2005-10-26
申请号：EP03796608.2
申请日：2003-12-03
CPC分类号： A61L12/143 , A61K31/16 , A61K31/22 , A61K31/23
摘要： The use of one or more quaternary ammonium ester compositions to disinfect contact lenses and preserve ophthalmic lens compositions is described. Ophthalmic lens compositions containing one or more quaternary ammonium ester compositions and methods of making and using the same are also described.
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