公开(公告)号：EP0697916A4

公开(公告)日：1996-06-26

申请号：EP95912699

申请日：1995-03-03

申请人： BAXTER INT

发明人： MOUBAYED AHMAD-MAHER ,  BURGESS JULIE D ,  LAW PING ,  KULCINSKI DAVID L ,  HARDWICK R ALAN

IPC分类号： G01N33/53 ,  A61M1/02 ,  A61M1/36 ,  B03C1/00 ,  B03C1/02 ,  B03C1/28 ,  C12M1/26 ,  C12M1/42 ,  C12M3/00 ,  C12N5/06 ,  C12N13/00 ,  G01N33/49 ,  G01N33/543 ,  B03C1/01 ,  B03C1/32 ,  G01N33/553

CPC分类号： C12M47/04 ,  A61M1/0209 ,  A61M1/3618 ,  A61M1/362 ,  B03C1/01 ,  B03C1/0332 ,  B03C1/28 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  G01N33/491

摘要： An apparatus and method for performing a magnetic cell separation process using paramagnetic beads, and having multiple steps or activitites which are required to complete the process successfully includes using a programmable machine (10) to either perform selected ones of the multiple steps itself; or to prompt a human attendant to perform others of said steps in sequence and to thereafter provide to the machine a verification input that the step to be performed by the human attendant is completed. The repeatability and reliability of the process when performed by the programmable machine (10) is vastly improved in comparison to conventional laboratory practice. Additionally, the programming of the machine (10) may be altered by super visory personnel to improve the efficacy of the process, or to customize the process for the separation of a particular type of cell.

摘要翻译： 一种使用顺磁珠执行磁性细胞分离过程并且具有成功完成该过程所需的多个步骤或活性的装置和方法包括使用可编程机器（10）来自己执行多个步骤中的选定步骤; 或者促使人类助理顺序地执行所述步骤中的其他步骤，并且随后向机器提供验证输入，以使得完成由人工助理执行的步骤。 与传统的实验室实践相比，由可编程机器（10）执行的过程的可重复性和可靠性大大提高。 此外，机器（10）的编程可以由超级观察员改变以改进过程的效力，或者定制用于分离特定类型的细胞的过程。