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1.发明公开MATERIEL NUCLEIQUE RETROVIRAL ET FRAGMENTS NUCLEOTIDIQUES NOTAMMENT ASSOCIES A LA SCLEROSE EN PLAQUES ET/OU LA POLYARTHRITE RHUMATOIDE, A DES FINS DE DIAGNOSTIC, PROPHYLACTIQUES ET THERAPEUTIQUES 失效诊断，预防与治疗多发性硬化和/或风湿性多关节炎ASSOCIATED RETRO病毒核酸和相关核苷酸片段
公开(公告)号：EP0996731A2
公开(公告)日：2000-05-03
申请号：EP98936467.4
申请日：1998-07-07
申请人： BIO MERIEUX
发明人： PARAHNOS-BACCALA, Glaucia , KOMURIAN-PRADEL, Florence , BEDIN, Frédéric , SODOYER, Mireille , OTT, Catherine , MALLET, François , PERRON, Hervé , MANDRAND, Bernard
CPC分类号： C07K14/4713 , C07K14/005 , C12N2740/10022
摘要： The invention concerns a nucleic material, in isolated or purified state, and a nucleotide fragment comprising a nucleotide sequence selected from the group consisting in (i) the sequences SEQ ID NO: 112, SEQ ID NO:114, SEQ ID NO: 117, SEQ ID NO: 120, SEQ ID NO. 124, SEQ ID NO: 130, SEQ ID NO: 141 and SEQ ID NO: 142, (ii) the complementary sequences of sequences (i); and (iii) the sequences equivalent to sequences (ii) and (iii), in particular the sequence having for every series of 100 contiguous monomers, at least 50 %, preferably 70 % homology with sequences (i) and (ii) respectively. The invention also concerns their uses for detecting a retrovirus associated with multiple sclerosis and/or rheumatoid arthritis.
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2.发明授权MATERIEL NUCLEIQUE RETROVIRAL ET FRAGMENTS NUCLEOTIDIQUES NOTAMMENT ASSOCIES A LA SCLEROSE EN PLAQUES ET/OU LA POLYARTHRITE RHUMATOIDE, A DES FINS DE DIAGNOSTIC, PROPHYLACTIQUES ET THERAPEUTIQUES 失效诊断，预防与治疗多发性硬化和/或风湿性多关节炎ASSOCIATED RETRO病毒核酸和相关核苷酸片段
公开(公告)号：EP0996731B1
公开(公告)日：2005-08-31
申请号：EP98936467.4
申请日：1998-07-07
申请人： BIO MERIEUX
发明人： PARAHNOS-BACCALA, Glaucia , KOMURIAN-PRADEL, Florence , BEDIN, Frédéric , SODOYER, Mireille , OTT, Catherine , MALLET, François , PERRON, Hervé , MANDRAND, Bernard
CPC分类号： C07K14/4713 , C07K14/005 , C12N2740/10022
摘要： The invention concerns a nucleic material, in isolated or purified state, and a nucleotide fragment comprising a nucleotide sequence selected from the group consisting in (i) the sequences SEQ ID NO: 112, SEQ ID NO:114, SEQ ID NO: 117, SEQ ID NO: 120, SEQ ID NO. 124, SEQ ID NO: 130, SEQ ID NO: 141 and SEQ ID NO: 142, (ii) the complementary sequences of sequences (i); and (iii) the sequences equivalent to sequences (ii) and (iii), in particular the sequence having for every series of 100 contiguous monomers, at least 50 %, preferably 70 % homology with sequences (i) and (ii) respectively. The invention also concerns their uses for detecting a retrovirus associated with multiple sclerosis and/or rheumatoid arthritis.
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