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公开(公告)号：EP0220030A2
公开(公告)日：1987-04-29
申请号：EP86307849.9
申请日：1986-10-10
发明人： Russell-Jones, Gregory John , De Aizpurua, Henry James , Howe, Peter Allan , Burge, Geoffery Lewis
CPC分类号： A61K39/00 , A61K39/385 , A61K47/54 , A61K2039/60
摘要： The present invention provides a complex of a drug, hormone, bio-active peptide, or immunoger with the carrier molecule vitamin B12 and a method for delivering said complex to the intestine of a host vertebrate in order to deliver the complex to the circulation of the host and thereby elicit a pharmacological response to the drug, hormone, or bio- active molecule orto elicit a systemic immune response to the immunogen. The invention also provides a method for the production of the complex. Further the invention provides medicaments containing the complex.
摘要翻译： 本发明提供药物，激素，生物活性肽或免疫原与载体分子维生素B12的复合物，以及用于将所述复合物递送至宿主脊椎动物的肠的方法，以将复合物递送至 从而引起对药物，激素或生物活性分子的药理学反应或引发对免疫原的全身免疫应答。 本发明还提供了一种生产复合物的方法。 此外，本发明提供了含有该复合物的药物。
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公开(公告)号：EP0220030B1
公开(公告)日：1991-06-19
申请号：EP86307849.9
申请日：1986-10-10
发明人： Russell-Jones, Gregory John , De Aizpurua, Henry James , Howe, Peter Allan , Burge, Geoffery Lewis
CPC分类号： A61K39/00 , A61K39/385 , A61K47/54 , A61K2039/60
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公开(公告)号：EP0220030A3
公开(公告)日：1987-09-30
申请号：EP86307849
申请日：1986-10-10
发明人： Russell-Jones, Gregory John , De Aizpurua, Henry James , Howe, Peter Allan , Burge, Geoffery Lewis
CPC分类号： A61K39/00 , A61K39/385 , A61K47/54 , A61K2039/60
摘要： The present invention provides a complex of a drug, hormone, bio-active peptide, or immunoger with the carrier molecule vitamin B12 and a method for delivering said complex to the intestine of a host vertebrate in order to deliver the complex to the circulation of the host and thereby elicit a pharmacological response to the drug, hormone, or bio- active molecule orto elicit a systemic immune response to the immunogen. The invention also provides a method for the production of the complex. Further the invention provides medicaments containing the complex.
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