公开(公告)号：EP0716689A1

公开(公告)日：1996-06-19

申请号：EP95925778.0

申请日：1995-06-28

申请人： BOEHRINGER INGELHEIM INTERNATIONAL GmbH

发明人： BEUG, Hartmut ,  WESSELY, Oliver ,  STEINLEIN, Peter ,  DEINER, Eva ,  VON LINDERN, Maartje, Marie

IPC分类号： C12N5

CPC分类号： C12N5/0641 ,  C12N2501/11 ,  C12N2501/125 ,  C12N2501/148 ,  C12N2501/392

摘要： A process for the in vitro production of non-immortalised haematopoetic precursor cells of the erythroid line in which a population of erythroid precursor cells is exposed to a combination of growth factors containing a glucocorticoid and an oestrogen and at least one ligand of a tyrosine kinase receptor until the cells begin to renew themselves spontaneously.

公开(公告)号：EP0716689B1

公开(公告)日：2002-10-02

申请号：EP95925778.3

申请日：1995-06-28

申请人： Boehringer Ingelheim International GmbH

发明人： BEUG, Hartmut ,  WESSELY, Oliver ,  STEINLEIN, Peter ,  DEINER, Eva ,  VON LINDERN, Maartje, Marie

IPC分类号： C12N5/00 ,  C12N5/08

CPC分类号： C12N5/0641 ,  C12N2501/11 ,  C12N2501/125 ,  C12N2501/148 ,  C12N2501/392

摘要： A process for the in vitro production of non-immortalised haematopoetic precursor cells of the erythroid line in which a population of erythroid precursor cells is exposed to a combination of growth factors containing a glucocorticoid and an oestrogen and at least one ligand of a tyrosine kinase receptor until the cells begin to renew themselves spontaneously.