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公开(公告)号：EP0843676A1
公开(公告)日：1998-05-27
申请号：EP96927638.0
申请日：1996-07-31
发明人： BANHOLZER, Rolf , REICHL, Richard , DISSE, Bernd , SPECK, Georg
CPC分类号： C07D451/10
摘要： The invention concerns the use of the salts of the L-(-)-enantiomer of (endo, syn)-(-)-3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(methylethyl)-8-azoniabicyclo[3.2.1] octane as active substances for medicaments administered by inhalation for treatment of the respiratory tract. These salts are suitable for such treatment owing to their unexpectedly intense and prolonged effect.
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2.发明公开
公开(公告)号：EP0579615A1
公开(公告)日：1994-01-26
申请号：EP92905643.0
申请日：1992-03-05
发明人： BANHOLZER, Rolf , BAUER, Rudolf , REICHL, Richard
CPC分类号： C07D451/10 , C07D451/14
摘要： De nouveaux composés répondant à la formule (I): AO-CO-Z, dans laquelle A et Z ont la signification donnée dans la description, peuvent être préparés selon des méthodes classiques; ils sont utiles comme substances actives dans des médicaments.
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3.发明公开MEDICAMENTS COMPRISING PDE IV INHIBITORS AND A NOVEL ANTICHOLINERGIC AND THEIR USE FOR TREATING RESPIRATORY DISORDERS 审中-公开产品含PDE IV抑制剂和抗胆碱能药NEW及其用于呼吸系统疾病的治疗
公开(公告)号：EP1651208A1
公开(公告)日：2006-05-03
申请号：EP04741118.6
申请日：2004-07-23
发明人： GERMEYER, Sabine , MEADE, Christopher, John, Montague , MEISSNER, Helmut , MORSCHHAEUSER, Gerd , PAIRET, Michel , PESTEL, Sabine , PIEPER, Michael, P. , POHL, Gerald , REICHL, Richard , SPECK, Georg
IPC分类号： A61K31/335 , A61K31/192 , A61K31/44 , A61P11/00 , A61K45/06 , A61K31/46
CPC分类号： A61K9/0075 , A61K9/0078 , A61K9/008 , A61K31/192 , A61K31/335 , A61K31/4015 , A61K31/44 , A61K31/46 , A61K31/4745 , A61K45/06 , A61K2300/00
摘要： The present invention relates to novel pharmaceutical compositions based on PDE IV inhibitors and salts of a new anticholinergic, processes for preparing them and their use in the treatment of respiratory complaints.
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4.发明授权MEDICAMENTS FOR INHALATION COMPRISING BETAMIMETICS AND AN ANTICHOLINERGIC AGENT 有权药物雾化吸入和β受体兴奋剂抗胆碱能
公开(公告)号：EP1651221B1
公开(公告)日：2009-01-14
申请号：EP04741115.2
申请日：2004-07-17
发明人： GERMEYER, Sabine , MEADE, Christopher, John, Montague , MEISSNER, Helmut , MORSCHHAEUSER, Gerd , PAIRET, Michel , PESTEL, Sabine , PIEPER, Michael, P. , POHL, Gerald , REICHL, Richard , SPECK, Georg , KONETZKI, Ingo
IPC分类号： A61K31/46 , A61K31/167 , A61K31/137 , A61K31/00 , A61P11/06 , A61K9/00
CPC分类号： A61K9/0075 , A61K9/008 , A61K31/00 , A61K31/137 , A61K31/167 , A61K31/46 , A61K2300/00
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5.发明授权
公开(公告)号：EP0579615B1
公开(公告)日：2001-07-04
申请号：EP92905643.0
申请日：1992-03-05
发明人： BANHOLZER, Rolf , BAUER, Rudolf , REICHL, Richard
IPC分类号： C07D451/10 , C07D451/14 , A61K31/46
CPC分类号： C07D451/10 , C07D451/14
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6.发明授权MEDICAMENTS FOR INHALATION COMPRISING STEROIDS AND A NOVEL FLUORENE CARBOXYLIC ACID ESTER 有权对于吸入药物类固醇和一个新的氟碳苯二甲酸酯
公开(公告)号：EP1651230B1
公开(公告)日：2009-07-01
申请号：EP04763306.0
申请日：2004-07-17
发明人： GERMEYER, Sabine , MEADE, Christopher, John, Montague , MEISSNER, Helmut , MORSCHHAEUSER, Gerd , PAIRET, Michel , PESTEL, Sabine , PIEPER, Michael, P. , POHL, Gerald , REICHL, Richard , SPECK, Georg
IPC分类号： A61K31/535 , A61K31/56 , A61K31/573 , A61K9/12 , C07D451/12 , A61P11/06
CPC分类号： A61K9/0075 , A61K9/008 , A61K31/535 , A61K31/56 , A61K31/573 , C07D451/12 , A61K2300/00
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7.发明公开
公开(公告)号：EP1651230A1
公开(公告)日：2006-05-03
申请号：EP04763306.0
申请日：2004-07-17
发明人： GERMEYER, Sabine , MEADE, Christopher, John, Montague , MEISSNER, Helmut , MORSCHHAEUSER, Gerd , PAIRET, Michel , PESTEL, Sabine , PIEPER, Michael, P. , POHL, Gerald , REICHL, Richard , SPECK, Georg
IPC分类号： A61K31/535 , A61K31/56 , A61K31/573 , A61K9/12 , C07D451/12 , A61P11/06
CPC分类号： A61K9/0075 , A61K9/008 , A61K31/535 , A61K31/56 , A61K31/573 , C07D451/12 , A61K2300/00
摘要： The present invention relates to novel pharmaceutical compositions based on steroids and salts of a new anticholinergic, processes for preparing them and their use in the treatment of respiratory complaints.
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8.发明公开
公开(公告)号：EP1651221A1
公开(公告)日：2006-05-03
申请号：EP04741115.2
申请日：2004-07-17
发明人： GERMEYER, Sabine , MEADE, Christopher, John, Montague , MEISSNER, Helmut , MORSCHHAEUSER, Gerd , PAIRET, Michel , PESTEL, Sabine , PIEPER, Michael, P. , POHL, Gerald , REICHL, Richard , SPECK, Georg , KONETZKI, Ingo
IPC分类号： A61K31/46 , A61K31/167 , A61K31/137 , A61K31/00 , A61P11/06 , A61K9/00
CPC分类号： A61K9/0075 , A61K9/008 , A61K31/00 , A61K31/137 , A61K31/167 , A61K31/46 , A61K2300/00
摘要： The present invention relates to novel pharmaceutical compositions based on beta2 agonists and salts of a new anticholinergic, processes for preparing them and their use in the treatment of respiratory complaints, wherein the anticholinergic agent has the formula (I).
摘要翻译： 本发明涉及基于β2激动剂和新型抗胆碱能药的盐的新型药物组合物，其制备方法及其在治疗呼吸疾病中的用途，其中抗胆碱能药具有式（I）。
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9.发明授权ARZNEIMITTELVORBEREITUNGEN ENTHALTEND EIN ENANTIOMER VON IPRATROPIUMBROMID MIT VERLÄNGERTER WIRKUNGSDAUER 失效DRUGS PREPARATIONS含异丙托溴铵的对映体延长的持续时间的影响
公开(公告)号：EP0843676B1
公开(公告)日：2001-11-07
申请号：EP96927638.5
申请日：1996-07-31
发明人： BANHOLZER, Rolf , REICHL, Richard , DISSE, Bernd , SPECK, Georg
IPC分类号： C07D451/10 , A61K31/46
CPC分类号： C07D451/10
摘要： The invention concerns the use of the salts of the L-(-)-enantiomer of (endo, syn)-(-)-3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(methylethyl)-8-azoniabicyclo[3.2.1] octane as active substances for medicaments administered by inhalation for treatment of the respiratory tract. These salts are suitable for such treatment owing to their unexpectedly intense and prolonged effect.
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