专利检索 ap:("BOEHRINGER INGELHEIM PHARMACEUTICALS INC.") AND inv:"Hammach, A.,Boehringer Ingelheim Pharm Inc." 第 1 页

1.

发明公开
FLUORINATED PHENYL-NAPHTHALENYL-UREA COMPOUNDS AS INHIBITORS OF CYTOKINES INVOLVED IN INFLAMMATORY PROCESSES 审中-公开
标题翻译：氟化苯基萘基脲衍生物的细胞因子的INHHIBITOREN在炎症过程中

公开(公告)号：EP1549621A1

公开(公告)日：2005-07-06

申请号：EP03784873.6

申请日：2003-08-01

申请人： BOEHRINGER INGELHEIM PHARMACEUTICALS INC.

发明人： Cirillo, Pier Fco,Boehringer Ingelheim Pharm Inc. , Hammach, A.,Boehringer Ingelheim Pharm Inc. , Kamhi, Victor,Boehringer Ingelheim Pharm. Inc. , Moss, Neil,Boehringer Ingelheim Pharm., Inc. , Riska, Paul S.,Boehringer Ingelheim Pharm. Inc. , Pargellis, C.,Boehringer Ingelheim Pharm. Inc.

IPC分类号： C07D239/34 , C07D239/46 , C07D403/12 , A61K31/505 , A61K31/506

CPC分类号： C07D249/08 , C07D231/12 , C07D233/56 , C07D239/34 , C07D239/47 , C07D239/52 , C07D401/12 , C07D405/12

摘要： Disclosed are compounds of formula (I) wherein R1, R2, W and X of formula (I) are defined herein. The compounds inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.