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公开(公告)号：EP1587523A2
公开(公告)日：2005-10-26
申请号：EP03815479.5
申请日：2003-09-11
发明人： ARBOGAST, Christophe , BUSSAT, Philippe , DRANSFIELD, Daniel, T. , FAN, Hong , LINDER, Karen , MARINELLI, Edmund, R. , NANJAPPAN, Palaniappa , NUNN, Adrian , PILLAI, Radhakrishna , POCHON, Sybille , RAMALINGAM, Kondareddiar , SATO, Aaron , SHRIVASTAVA, Ajay , SONG, Bo , SWENSON, Rolf, E. , VON WRONSKI, Mathew, A. , WALKER, Sharon, Michele
摘要： The invention provides compositions and methods for therapeutic and diagnostic applications.
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公开(公告)号：EP1482987A1
公开(公告)日：2004-12-08
申请号：EP03726024.7
申请日：2003-03-03
发明人： ARBOGAST, Christophe , BUSSAT, Philippe , DRANSFIELD, Daniel, T. , FAN, Hang , LINDER, Karen, E. , MARINELLI, Edmund, R. , NANJAPPAN, Palaniappa , NUNN, Adrian , PILLAI, Radhakrishna , POCHON, Sibylle , RAMALINGAM, Kondareddiar , SATO, Aaron , SHRIVASTAVA, Ajay , SONG, Bo , SWENSON, Rolf, E. , VON WRONSKI, Mathew, A. , WALKER, Sharon, Michele
摘要： The invention provides compositions and methods for therapeutic and diagnostic applications such as that shown in Figure 36.
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3.发明公开KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY 审中-公开KDR和VEGF / KDR结合肽及其用途的诊断与治疗
公开(公告)号：EP1572724A2
公开(公告)日：2005-09-14
申请号：EP03711418.8
申请日：2003-03-03
发明人： SATO, Aaron, K. , SEXTON, Daniel, J. , LADNER, Robert, C. , DRANSFIELD, Daniel, T. , SWENSON, Rolf, E. , MARINELLI, Edmund, R. , RAMALINGAM, Kondareddiar , NUNN, Adrian, D. , VON WRONSKI, Mathew, A. , SHRIVASTAVA, Ajay , POCHON, Sibylle , BUSSAT, Philippe , ARBOGAST, Christophe , PILLAI, Radhakrishna , FAN, Hong , LINDER, Karen, E. , SONG, Bo , NANJAPPAN, Palaniappa
IPC分类号： C07K7/00
CPC分类号： C07K7/08 , A61K38/00 , A61K49/223 , A61K51/088 , C07K14/001 , C07K14/52 , C07K14/71 , C07K2319/00 , Y02A50/411 , Y02A50/58
摘要： The present invention provides binding polypeptides for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity ( e . g ., having a K D
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4.发明公开KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY 审中-公开KDR和VEGF / KDR结合肽及其诊断和治疗用途VERA诊断与治疗
公开(公告)号：EP1587944A1
公开(公告)日：2005-10-26
申请号：EP03770325.3
申请日：2003-09-11
发明人： SATO, Aaron, K. , SEXTON, Daniel, J. , DRANSFIELD, Daniel, T. , LADNER, Robert, C. , ARBOGAST, Christophe , BUSSAT, Philippe , FAN, Hong , KHURANA, Sudha , LINDER, Karen, E. , MARINELLI, Edmund, R. , NANJAPPAN, Palaniappa , NUNN, Adrian , PILLAI, Radhakrishna , POCHON, Sibylle , RAMALINGAM, Kondareddiar , SHRIVASTAVA, Ajay , SONG, Bo , SWENSON, Rolf E. , VON WRONSKI, Mathew A.
CPC分类号： A61K49/221 , A61K38/00 , A61K47/62 , A61K49/223 , A61K51/088 , C07K7/08 , C07K14/001 , C07K14/52 , C07K14/71 , C07K2319/00 , Y02A50/411 , Y02A50/58
摘要： The present invention provides polypeptides, peptide dimer, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a KD
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