公开(公告)号：EP0754178B1

公开(公告)日：2003-01-15

申请号：EP95913298.6

申请日：1995-04-06

申请人： Bayer Corporation

发明人： LAW, Say-Jong ,  SOTIRIOU-LEVENTIS, Chariklia ,  NATRAJAN, Anand ,  JIANG, Qingping ,  CONNOLLY, Peter, B. ,  KILROY, John, P. ,  MCCUDDEN, Constance, R. ,  TIRRELL, Stephen, M.

IPC分类号： C07D219/04 ,  G01N33/533 ,  G01N33/58 ,  C07J43/00

CPC分类号： C07D401/12 ,  C07D219/04 ,  C07F9/64 ,  C07J1/0011 ,  C07J1/0022 ,  C07J21/006 ,  C07J43/003 ,  C12Q1/6816 ,  G01N33/533 ,  G01N33/586 ,  C12Q2563/161 ,  C12Q2563/103

摘要： Novel acridinium esters that are useful, either alone or when incorporated into liposomes, as chemiluminescent agents in binding assays (e.g., immunoassays and gene probe assays) with improved sensitivity are disclosed. In addition, the synthesis of these esters and their use in assays for detecting an analyte is described. In particular, assays for testosterone and the Rubella virus are disclosed.