公开(公告)号：EP1644339A1

公开(公告)日：2006-04-12

申请号：EP04739944.9

申请日：2004-06-16

申请人： Bayer HealthCare AG

发明人： HENDRIX, Martin ,  BÄRFACKER, Lars ,  BEYREUTHER, Bettina ,  EBERT, Ulrich ,  ERB, Christina ,  HAFNER, Frank-Thorsten ,  HECKROTH, Heike ,  LIU, Yan-Hong ,  KARTHAUS , Dagmar ,  TERSTEEGEN, Adrian ,  VAN DER STAAY, Franz-Josef ,  VAN KAMPEN, Marja

IPC分类号： C07D239/42 ,  C07D401/12 ,  C07D409/12 ,  A61K31/505 ,  A61K31/506 ,  A61P25/28

CPC分类号： C07D239/42 ,  C07D401/12 ,  C07D409/12

摘要： The invention relates to novel 6-arylamino-5-cyano-4-pyrimidinones of formula (I), methods for the production thereof, and the use thereof for producing medicaments utilized for improving awareness, concentration, learning capacity, and/or retentiveness of memory. Said compounds (I) show activity as PDE9 inhibitors.