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公开(公告)号:EP1828233A2
公开(公告)日:2007-09-05
申请号:EP05819949.8
申请日:2005-12-13
申请人: Bayer HealthCare AG
发明人: REINEMER, Peter , GIELEN-HAERTWIG, Heike , ROSENTRETER, Ulrich , LI, Volkhart , HARRENGA, Axel , SCHOMBURG, Dietmar , NIEFIND, Karsten , HANSEN, Guido, c/o Biota Structural Biology Lab.
IPC分类号: C07K14/435 , C07D239/22
CPC分类号: C07D239/36 , C07K2299/00 , C12N9/6448 , C12Y304/21037
摘要: This invention relates to crystallised human neutrophil elastase and the use of its three-dimensional structure to design modulators for human neutrophil elastase.