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公开(公告)号:EP3157914A1
公开(公告)日:2017-04-26
申请号:EP15730130.0
申请日:2015-06-17
发明人: GRAHAM, Keith , KLAR, Ulrich , BRIEM, Hans , HITCHCOCK, Marion , BÄRFACKER, Lars , EIS, Knut , SCHULZE, Volker , SIEMEISTER, Gerhard , BONE, Wilhelm , SCHRÖDER, Jens , HOLTON, Simon , LIENAU, Philip , TEMPEL, René , SONNENSCHEIN, Helmut , BÁLINT, Jozsef , GRAUBAUM, Heinz
IPC分类号: C07D401/14 , C07D405/14 , C07D401/04 , C07D403/04 , C07D409/14 , C07D417/14 , C07D471/04 , C07D491/056 , A61K31/4439 , A61K31/444 , A61K31/506 , A61P35/00
CPC分类号: C07D401/04 , A61K31/436 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/4709 , A61K31/4725 , A61K31/501 , A61K31/506 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D491/056
摘要: Compounds of formula (I) which are inhibitors of Bub1 kinase, processes for their production and their use as pharmaceuticals.
摘要翻译: 作为Bub1激酶抑制剂的式(I)化合物,其制备方法及其作为药物的用途。
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公开(公告)号:EP3250567B1
公开(公告)日:2019-10-30
申请号:EP16701600.5
申请日:2016-01-25
发明人: GRAHAM, Keith , KLAR, Ulrich , BRIEM, Hans , SCHULZE, Volker , SIEMEISTER, Gerhard , LIENAU, Philip , TEMPEL, René , BÁLINT, Jozsef
IPC分类号: C07D405/14 , C07D401/12 , C07D471/04 , A61K31/437 , A61P35/00
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公开(公告)号:EP3157914B1
公开(公告)日:2018-09-26
申请号:EP15730130.0
申请日:2015-06-17
发明人: GRAHAM, Keith , KLAR, Ulrich , BRIEM, Hans , HITCHCOCK, Marion , BÄRFACKER, Lars , EIS, Knut , SCHULZE, Volker , SIEMEISTER, Gerhard , BONE, Wilhelm , SCHRÖDER, Jens , HOLTON, Simon , LIENAU, Philip , TEMPEL, René , SONNENSCHEIN, Helmut , BÁLINT, Jozsef , GRAUBAUM, Heinz
IPC分类号: C07D401/14 , C07D405/14 , C07D401/04 , C07D403/04 , C07D409/14 , C07D417/14 , C07D471/04 , C07D491/056 , A61K31/4439 , A61K31/444 , A61K31/506 , A61P35/00
CPC分类号: C07D401/04 , A61K31/436 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/4709 , A61K31/4725 , A61K31/501 , A61K31/506 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D491/056
摘要: Compounds of formula (I) which are inhibitors of Bub1 kinase, processes for their production and their use as pharmaceuticals.
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公开(公告)号:EP3250567A1
公开(公告)日:2017-12-06
申请号:EP16701600.5
申请日:2016-01-25
发明人: GRAHAM, Keith , KLAR, Ulrich , BRIEM, Hans , SCHULZE, Volker , SIEMEISTER, Gerhard , LIENAU, Philip , TEMPEL, René , BÁLINT, Jozsef
IPC分类号: C07D405/14 , C07D401/12 , C07D471/04 , A61K31/437 , A61P35/00
摘要: Compounds of formula (I), processes for their production and their use as pharmaceuticals.
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