-
1.发明公开
公开(公告)号：EP2429589A2
公开(公告)日：2012-03-21
申请号：EP10720543.7
申请日：2010-05-06
IPC分类号： A61K49/04
CPC分类号： A61K49/0433 , A61K49/0438
摘要： The invention relates to a diagnostic or therapeutic composition comprising a monomeric X-ray contrast medium containing iodine, in particular iopromide, for use in an X-ray assisted diagnosis or therapy and for the use of high doses of an X-ray contrast medium given to a patient, in particular patients with restricted kidney function.
-
公开(公告)号：EP3544964A1
公开(公告)日：2019-10-02
申请号：EP17803952.5
申请日：2017-11-24
发明人： BERGER, Markus , LOHRKE, Jessica , HILGER, Christoph-Stephan , JOST, Gregor , FRENZEL, Thomas , PANKNIN, Olaf , PIETSCH, Hubertus
IPC分类号： C07D257/02 , A61K49/10
-
公开(公告)号：EP3295197B1
公开(公告)日：2019-03-20
申请号：EP16722164.7
申请日：2016-05-10
IPC分类号： G01R33/28 , G01R33/563 , A61B5/00 , G01F1/00 , G06F19/00
-
4.发明公开METAL CHELATE COMPOUNDS FOR BINDING TO THE PLATELET SPECIFIC GLYCOPROTEIN IIB/IIIA 审中-公开METALLCHELATVERBINDUNGEN ZUR BINDUNG AN DAS THROMBOZYTENSPEZIFISCHE GLYKOPROTEIN IIB / IIIA
公开(公告)号：EP3105221A1
公开(公告)日：2016-12-21
申请号：EP15702798.8
申请日：2015-02-06
IPC分类号： C07D401/14 , A61K49/06
CPC分类号： C07D401/14 , A61K49/108
摘要： The present invention is directed to compounds that bind to glycoprotein IIb/IIIa and can be used for diagnostic imaging, in particular magnetic resonance imaging of thrombi. The disclosed compounds enable the binding to glycoprotein IIb/IIIa receptor combined with an adequate imaging sensitivity.
摘要翻译： 本发明涉及结合糖蛋白IIb / IIIa并可用于诊断成像，特别是血栓的磁共振成像的化合物。 所公开的化合物使得能够结合具有足够成像敏感性的糖蛋白IIb / IIIa受体结合。
-
公开(公告)号：EP3883613A1
公开(公告)日：2021-09-29
申请号：EP19805322.5
申请日：2019-11-21
-
公开(公告)号：EP3303307B1
公开(公告)日：2019-09-04
申请号：EP16726531.3
申请日：2016-05-30
发明人： BERGER, Markus , LOHRKE, Jessica , HILGER, Christoph-Stephan , JOST, Gregor , FRENZEL, Thomas , SÜLZLE, Detlev , PLATZEK, Johannes , PANKNIN, Olaf , PIETSCH, Hubertus
IPC分类号： C07D257/02 , C07C229/16 , A61K49/10
-
公开(公告)号：EP2988787A1
公开(公告)日：2016-03-02
申请号：EP14719711.5
申请日：2014-04-22
发明人： BERGER, Markus , SÜLZLE, Detlev , FRENZEL, Thomas , GRAHAM, Keith , JOST, Gregor , NEIS, Christian , HEGETSCHWEILER, Kaspar , PIETSCH, Hubertus
CPC分类号： C07C229/76 , A61K49/0409 , C07C227/18 , C07C2601/14 , C07F7/00
摘要： The present invention describes a new class of trinuclear hafnium complexes comprising two hexadentate azainositol carboxylic acid ligands, methods for their preparation and their use as X-ray contrast agents and X-ray diagnostic agents. The claimed compounds can be described by the following Markush formula describing rinuclear hafnium complexes of general formula (I). The following is a compound according to the above Markush formula (example 8).
摘要翻译： 本发明描述了一类新的三核铪配合物，其包含两个六齿氮杂糖醇羧酸配体，它们的制备方法以及它们作为X射线造影剂和X射线诊断剂的用途。 要求保护的化合物可以通过描述通式（I）的核核铪配合物的以下马库舒公式描述。 以下是根据上述马库什公式（实施例8）的化合物。
-
8.发明公开
公开(公告)号：EP3303307A1
公开(公告)日：2018-04-11
申请号：EP16726531.3
申请日：2016-05-30
发明人： BERGER, Markus , LOHRKE, Jessica , HILGER, Christoph-Stephan , JOST, Gregor , FRENZEL, Thomas , SÜLZLE, Detlev , PLATZEK, Johannes , PANKNIN, Olaf , PIETSCH, Hubertus
IPC分类号： C07D257/02 , C07C229/16 , A61K49/10
CPC分类号： A61K49/106 , C07D257/02
摘要： The present invention relates to a new class of high relaxivity extracellular gadolinium chelate complexes, to methods of preparing said compounds, and to the use of said compounds as MRI contrast agents.
-
9.发明公开METAL CHELATE COMPOUNDS FOR BINDING TO THE PLATELET SPECIFIC GLYCOPROTEIN IIB/IIIA 审中-公开金属螯合物的约束通过特定血小板糖蛋白IIb / IIIa受体
公开(公告)号：EP2956461A1
公开(公告)日：2015-12-23
申请号：EP14704328.5
申请日：2014-02-11
IPC分类号： C07F5/00
CPC分类号： A61K49/14 , A61K49/085 , A61K49/124 , C07D401/14 , C07F5/00 , C07F5/003
摘要： The present invention is directed to compounds that bind to glycoprotein IIb/IIIa and can be used for diagnostic imaging, in particular magnetic resonance imaging of thrombi. The disclosed compounds enable the binding to glycoprotein IIb/IIIa receptor combined with an adequate relaxivity.
-
公开(公告)号：EP2849804A1
公开(公告)日：2015-03-25
申请号：EP13720854.2
申请日：2013-04-25
发明人： BERGER, Markus , SCHMITT-WILLICH, Heribert , SÜLZLE, Detlev , PIETSCH, Hubertus , FRENZEL, Thomas , JOST, Gregor , HEGETSCHWEILER, Kaspar , NEIS, Christian , LAURIA, Silvia
IPC分类号： A61K49/04
摘要： The present invention describes a new class of trinuclear heavy metal complexes comprising two hexadentate azainositol tricarboxylic acid ligands, a method for their preparation and their use as X-ray contrast agents.
-
-
-
-
-
-
-
-
-
搜索结果
10 条记录 (耗时 0.015 秒)
