专利检索 ap:("Baylor Research Institute") AND inv:"NI, Ling" 第 1 页

1.

发明授权
THERAPEUTIC APPLICATIONS OF ACTIVATION OF HUMAN ANTIGEN-PRESENTING CELLS THROUGH DECTIN-1 有权
标题翻译：细胞与人抗原的BY的Dectin-1的活化治疗应用

公开(公告)号：EP2129773B1

公开(公告)日：2013-02-13

申请号：EP08799678.1

申请日：2008-02-22

申请人： Baylor Research Institute

发明人： BANCHEREAU, Jacques, F. , OH, SangKon , ZURAWSKI, Gerard , ZURAWSKI, Sandra , NI, Ling

IPC分类号： C12N5/07 , A61K39/395 , C07K16/28

CPC分类号： C07K16/2851 , A61K39/395 , A61K2039/5154 , A61K2039/5158 , C07K16/1018 , C07K2317/24 , C07K2317/74 , C07K2317/92 , C07K2319/00 , C12N5/0639 , C12N9/2402 , C12N2501/22 , C12N2501/23 , C12N2501/50 , C12N2501/998

2.

发明公开
ENHANCEMENT OF PATHOGEN-SPECIFIC MEMORY TH17 CELL RESPONSES 审中-公开
标题翻译：改进病原体TH17记忆细胞反应

公开(公告)号：EP2635305A1

公开(公告)日：2013-09-11

申请号：EP11838568.1

申请日：2011-10-27

申请人： Baylor Research Institute

发明人： OH, SangKon , BANCHEREAU, Jacques F. , ZURAWSKI, Gerard , UENO, Hideki , NI, Ling

IPC分类号： A61K39/395 , A61K39/145 , A61P37/02 , A61K39/00 , A61P31/16

CPC分类号： C07K16/2851 , A61K39/12 , A61K39/145 , A61K39/385 , A61K39/39 , A61K47/36 , A61K47/42 , A61K2039/55572 , A61K2039/6056 , C07K2317/76 , C07K2319/035 , C12N2760/16134

摘要： Compositions and methods for enhancing Th1/Th17 cell responses and decreasing Th2 cell responses are disclosed herein. In various embodiments the present invention describes activation of human dendritic cells and enhancement of antigen-specific T cell responses in a Dectin-1-expressing human dendritic cells comprising an anti-Dectin-1-specific antibody or fragment thereof fused with one or more antigens. TLR2 ligands may also be included to enhance the activation and for enhancement of T-cell responses. Further, the invention also includes methods based on the compositions described herein for the treatment of pathogenic infections.

3.

发明公开
THERAPEUTIC APPLICATIONS OF ACTIVATION OF HUMAN ANTIGEN-PRESENTING CELLS THROUGH DECTIN-1 有权
标题翻译：细胞与人抗原的BY的Dectin-1的活化治疗应用

公开(公告)号：EP2129773A2

公开(公告)日：2009-12-09

申请号：EP08799678.1

申请日：2008-02-22

申请人： Baylor Research Institute

发明人： BANCHEREAU, Jacques, F. , OH, SangKon , ZURAWSKI, Gerard , ZURAWSKI, Sandra , NI, Ling

IPC分类号： C12N5/06

CPC分类号： C07K16/2851 , A61K39/395 , A61K2039/5154 , A61K2039/5158 , C07K16/1018 , C07K2317/24 , C07K2317/74 , C07K2317/92 , C07K2319/00 , C12N5/0639 , C12N9/2402 , C12N2501/22 , C12N2501/23 , C12N2501/50 , C12N2501/998

摘要： The present invention includes compositions and methods for binding Dectin-1 on immune cells with anti-Dectin-1 -specific antibodies or fragment thereof capable of activating the immune cells.