公开(公告)号：EP1174084B1

公开(公告)日：2003-06-18

申请号：EP01126654.1

申请日：1998-03-03

申请人： Becton Dickinson and Company

发明人： Newby, Mark C. ,  Miller, Henry F. ,  Schleiffer, Keith E.

IPC分类号： A61B5/15 ,  B65D41/04

CPC分类号： A61B5/150732 ,  A61B5/15003 ,  A61B5/150259 ,  A61B5/150351 ,  A61B5/150389 ,  A61B5/150496 ,  A61B5/150572 ,  A61B5/1545 ,  B65D41/0471 ,  B65D51/002

公开(公告)号：EP0867378B1

公开(公告)日：2002-10-09

申请号：EP98103704.7

申请日：1998-03-03

申请人： Becton Dickinson and Company

发明人： Newby, Mark C. ,  Miller, Henry F. ,  Schleiffer, Keith E.

IPC分类号： A61B5/15 ,  B65D51/00 ,  B65D41/04

CPC分类号： A61B5/154 ,  A61B5/15003 ,  A61B5/150259 ,  A61B5/150351 ,  A61B5/150389 ,  A61B5/150496 ,  A61B5/150572 ,  A61B5/150732 ,  B65D51/002

公开(公告)号：EP0867378A3

公开(公告)日：2000-08-23

申请号：EP98103704.7

申请日：1998-03-03

申请人： Becton, Dickinson and Company

发明人： Newby, Mark C. ,  Miller, Henry F. ,  Schleiffer, Keith E.

IPC分类号： A61B5/14 ,  B65D51/00 ,  B65D41/04

CPC分类号： A61B5/154 ,  A61B5/15003 ,  A61B5/150259 ,  A61B5/150351 ,  A61B5/150389 ,  A61B5/150496 ,  A61B5/150572 ,  A61B5/150732 ,  B65D51/002

摘要： An assembly (10) for collecting blood or other body fluids is provided. The assembly (10) includes an elongate tube (12) having an open end and a closed end. The open end includes threads. An internally threaded plastic cap (22) is mounted to the open end of the tube (12). The cap (22) includes an axial passage and a resealable member (24) aligned with the axial passage. A gas-impermeable member (44) is bonded to the resealable member (24) and the open end of the tube. Both the resealable member (24) and gas-impermeable member (44) are pierceable by a needle (18). The cap (22) is removable with the resealable member (24) and the gas-impermeable member (44) as a unit due to the fact that the bond between the gas-impermeable member (44) and the tube is weaker than that between the gas-impermeable member (44) and the resealable member (24). The cap (22) includes a deflectable portion (28) near its top end to engage the walls of a tube holder (16), and to function as a shock absorber if the tube (12) is dropped.

公开(公告)号：EP1014088A2

公开(公告)日：2000-06-28

申请号：EP99124304.9

申请日：1999-12-06

申请人： Becton, Dickinson and Company

发明人： Lin, Fu-Chung ,  Losada, Robert Joseph ,  DiCesare, Paul C. ,  Miller, Henry F. ,  Cohen, Richmond

IPC分类号： G01N33/49

CPC分类号： G01N33/491 ,  B01L3/50215

摘要： A device and method is provided for separating heavier and lighter fractions of a fluid sample. The device includes a plurality of constituents comprising a container and a composite element in the container. The composite element is a separator comprising at least two components and more particularly an elastic portion and a plug member. A fluid sample is delivered to the container and the device is subjected to centrifugation whereby the centrifugal load causes the elastic portion of the separator to deform so that the separator migrates into the fluid sample and stabilizes between the heavier and lighter fractions of the fluid sample. The elastic portion of the separator will resiliently return to its initial configuration upon termination of the centrifugal load such that the elastic portion sealingly engages the container and separates the heavier and lighter fractions of the fluid sample.

摘要翻译： 提供了用于分离流体样品的较重和较轻馏分的装置和方法。 该装置包括多个构件，其包括容器中的容器和复合元件。 复合元件是包括至少两个部件，更具体地是弹性部分和塞子部件的分离器。 将流体样品输送到容器并且使装置进行离心，由此离心负载使得分离器的弹性部分变形，使得分离器迁移到流体样品中并且稳定在流体样品的较重和较轻部分之间。 当离心负载终止时，分离器的弹性部分将弹性地返回到其初始构型，使得弹性部分密封地接合容器并分离流体样品的较重和较轻的部分。

公开(公告)号：EP1005909A2

公开(公告)日：2000-06-07

申请号：EP99124313.0

申请日：1999-12-06

申请人： Becton, Dickinson and Company

发明人： Miller, Henry F. ,  DiCesare, Paul

IPC分类号： B01L3/14

CPC分类号： B01L3/50215

摘要： A device and method is provided for separating heavier and lighter fractions of a fluid sample. The device includes a plurality of constituents. The constituents include a container, a liner in the container and a composite element in the liner for separating the fractions of a fluid sample. The separator comprises a specific density at a target density range as defined by separable fluid components densities. A fluid sample is delivered to the liner and then the device is subjected to centrifugation whereby the centrifugal load causes the liner to deform and the composite element migrates into the fluid sample and stabilizes between the heavier and lighter fractions of the fluid sample. The liner will resiliently return to its initial configuration upon termination of the centrifugal load such that the liner sealingly engages the composite element and separates the heavier and lighter fractions of the fluid sample

摘要翻译： 提供了用于分离流体样品的较重和较轻馏分的装置和方法。 该装置包括多个成分。 组分包括容器，容器中的衬垫和用于分离流体样品的级分的衬套中的复合元件。 分离器包括由可分离的流体组分密度定义的目标密度范围的特定密度。 将流体样品输送到衬垫上，然后使装置进行离心，由此离心负载导致衬套变形，并且复合元件迁移到流体样品中并且稳定在流体样品的较重和较轻部分之间。 衬垫将在离心负载终止时弹性地返回到其初始构型，使得衬套密封地接合复合元件并且分离流体样品的重和较轻的部分

公开(公告)号：EP1174085B1

公开(公告)日：2003-07-09

申请号：EP01126655.8

申请日：1998-03-03

申请人： Becton Dickinson and Company

发明人： Newby, Mark C. ,  Miller, Henry F. ,  Schleiffer, Keith E.

IPC分类号： A61B5/15 ,  B65D41/04

CPC分类号： A61B5/150732 ,  A61B5/15003 ,  A61B5/150259 ,  A61B5/150351 ,  A61B5/150389 ,  A61B5/150496 ,  A61B5/150572 ,  A61B5/1545 ,  B65D41/0471 ,  B65D51/002

公开(公告)号：EP1174085A1

公开(公告)日：2002-01-23

申请号：EP01126655.8

申请日：1998-03-03

申请人： Becton, Dickinson and Company

发明人： Newby, Mark C. ,  Miller, Henry F. ,  Schleiffer, Keith E.

IPC分类号： A61B5/15 ,  B65D41/04

CPC分类号： A61B5/150732 ,  A61B5/15003 ,  A61B5/150259 ,  A61B5/150351 ,  A61B5/150389 ,  A61B5/150496 ,  A61B5/150572 ,  A61B5/1545 ,  B65D41/0471 ,  B65D51/002

摘要： An assembly for collecting blood or other body fluids is provided. The assembly includes an elongate tube (12) having an open end and a closed end. An internally threaded plastic cap (22) is mounted to the open end of the tube. The cap includes an axial passage (34) and a resealable member (24) aligned with the axial passage. A gas-impermeable member (44) is bonded to the resealable member and the open end of the tube. Both the resealable member and gas-impermeable member are pierceable by a needle. The cap includes a deflectable portion (28) near its top end to engage the walls of a tube holder (16), and to function as a shock absorber if the tube is dropped.

摘要翻译： 提供了用于收集血液或其他体液的组件。 该组件包括具有开口端和封闭端的细长管（12）。 内螺纹塑料盖（22）安装在管的开口端。 帽包括轴向通道（34）和与轴向通道对齐的可再密封元件（24）。 不可透气部件（44）粘合到可再密封部件和管的开口端。 可再密封元件和不透气元件都可用针刺穿。 帽包括靠近其顶端的可偏转部分（28）以接合管夹持器（16）的壁，并且如果管落下，则用作减震器。

公开(公告)号：EP1174084A1

公开(公告)日：2002-01-23

申请号：EP01126654.1

申请日：1998-03-03

申请人： Becton, Dickinson and Company

发明人： Newby, Mark C. ,  Miller, Henry F. ,  Schleiffer, Keith E.

IPC分类号： A61B5/15 ,  B65D41/04

CPC分类号： A61B5/150732 ,  A61B5/15003 ,  A61B5/150259 ,  A61B5/150351 ,  A61B5/150389 ,  A61B5/150496 ,  A61B5/150572 ,  A61B5/1545 ,  B65D41/0471 ,  B65D51/002

摘要： An assembly for collecting blood or other body fluids is provided. The assembly includes an elongate tube (12) having an open end and a closed end. The open end includes threads (20). An internally threaded plastic cap (22) is mounted to the open end of the tube. The cap includes an axial passage (34) and a resealable member (24) aligned with the axial passage. A gas-impermeable member (44) is bonded to the resealable member (24) and the open end of the tube. Both the resealable member and gas-impermeable member are pierceably by a needle. The tube (17) includes external interrupt threads (20) and the cap (22) includes a plurality of internal threads, each of which has a lead portion. The cap (22) further includes locating tabs (40) positioned adjacent the leading portions of the internal threads, for facilitating the engagement of the tube threads (20) and the cap threads (38).

摘要翻译： 提供了一种用于收集血液或其他体液的组件。 组件包括具有开口端和闭合端的细长管（12）。 开口端包括螺纹（20）。 内螺纹塑料盖（22）安装到管的开口端。 盖包括与轴向通道对准的轴向通道（34）和可重新密封的构件（24）。 气体不可渗透构件（44）结合到可再密封构件（24）和管的开口端。 可再密封构件和气体不可渗透构件都可以被针刺穿。 管（17）包括外部中断螺纹（20），盖（22）包括多个内螺纹，每个内螺纹具有引导部分。 盖（22）还包括邻近内螺纹的引导部分定位的定位凸片（40），以便于管螺纹（20）和盖螺纹（38）的接合。

公开(公告)号：EP0867378A2

公开(公告)日：1998-09-30

申请号：EP98103704.7

申请日：1998-03-03

申请人： Becton, Dickinson and Company

发明人： Newby, Mark C. ,  Miller, Henry F. ,  Schleiffer, Keith E.

IPC分类号： B65D51/00

CPC分类号： A61B5/154 ,  A61B5/15003 ,  A61B5/150259 ,  A61B5/150351 ,  A61B5/150389 ,  A61B5/150496 ,  A61B5/150572 ,  A61B5/150732 ,  B65D51/002

摘要： An assembly for collecting blood or other body fluids is provided. The assembly includes an elongate tube having an open end and a closed end. The open end includes threads. An internally threaded plastic cap is mounted to the open end of the tube. The cap includes an axial passage and a resealable member aligned with the axial passage. A gas-impermeable member is bonded to the resealable member and the open end of the tube. Both the resealable member and gas-impermeable member are pierceable by a needle. The cap is removable with the resealable member and the gas-impermeable member as a unit due to the fact that the bond between the gas-impermeable member and the tube is weaker than that between the gas-impermeable member and the resealable member. The cap includes a deflectable portion near its top end to engage the walls of a tube holder, and to function as a shock absorber if the tube is dropped.

摘要翻译： 提供了一种用于收集血液或其他体液的组件。 组件包括具有开口端和封闭端的细长管。 开放端包括线程。 内螺纹塑料盖安装在管的开口端。 盖包括轴向通道和与轴向通道对准的可再密封构件。 气体不可渗透构件结合到可再密封构件和管的开口端。 可再密封构件和气体不可渗透构件都可以被针刺穿。 由于气体不可渗透构件和管之间的结合弱于气体不可渗透构件和可再密封构件之间的事实，盖可拆卸，可再密封构件和气体不可渗透构件作为一个单元。 盖子包括靠近其顶端的可偏转部分，以与管保持器的壁接合，并且如果管子掉落，起到减震器的作用。