摘要:
A container is provided for holding a chemical compound or mixture. Areas are provided on the surface of the container which allow for gaseous by-products from the chemical contained within the container to permeate from a chamber through the surface of the container. A septum is over-molded into the surface of the container. The septum is formed in such a manner that it provides a sealing effect to close an opening in the container.
摘要:
A device includes a first part having a co-molded first support, valve cover and elastic actuator, and a second part having an injection molded second support, valve seat, and variable-volume storage chamber pre-form. The pre-form is blow molded into a flexible pouch defining the variable-volume storage chamber. The one-way valve includes a semi-annular, curvilinear, relatively rigid valve seat defining axially-extending, opposing first marginal portions, and an axially-extending first mid-portion angularly extending between the opposing first marginal portions. A flexible valve member is superimposed on the valve seat and defines axially-extending, opposing second marginal portions fixedly secured on or adjacent to respective first marginal portions of the valve seat, and an axially-extending second mid-portion angularly extending between the opposing first marginal portions and superimposed onto the first mid-portion of the valve seat. The flexible valve cover and valve seat form a normally closed axially and angularly extending valve seam therebetween.
摘要:
The present invention relates to a closure system (1) for bottles containing lyophilized or liquid products, particularly injectable or perfusable pharmaceutical products, comprising: - a perforable closure body (3) adapted to close the mouth (5) of a bottle (7); - an inner capsule (9), able to be fitted onto the neck (11) of the bottle (7), configured to hold the closure body (3) in a sealed closure configuration of the mouth (5) of the bottle (7), in which the inner capsule (9) comprises an opening (13) adapted for allowing access to the closure body (3); - an outer capsule (15), able to be fitted onto the inner capsule (9). The peculiarity of the invention consists in the fact that the outer capsule (15) is made in a single body and comprises an upper disc-shaped portion (17) configured to close the opening (13) of the inner capsule (9) and a lower portion (19) able to be fitted around the inner capsule (9), in which the outer capsule (15) comprises a breaking line (21) between the upper disc-shaped portion (17) and the lower portion (19) .
摘要:
Vessel closures having a variety of inserts for aseptically sealing vessels. The vessel closures have a body with one or more apertures, one or more inserts extending axially through the one or more apertures, and a cast seal surrounding the inserts. The cast seal is preferably east silicone. The vessel closures may have one or more anchors securing the inserts to the body of the vessel closure. Also disclosed are methods of manufacturing vessel closures and a method of using the vessel closures disclosed herein for circulating fluids into and out of a vessel while also having the ability to regulate the temperature of the pumped fluid.
摘要:
A breakseal providing desired compliance characteristics for a reliable seal between the fitment of a liquid dispenser and the breakseal. A compliant material is provided on the non-wetted face of the breakseal, enabling compliance of the breakseal on a wetted face for sealing between the breakseal and the mating component. The breakseal may also include raised features on segments that are separated after rupturing that prevent or mitigate scoring of O-ring seals upon probe insertion. A wiping feature that provides redundant sealing between the breakseal and a mating cap or other mating connection may also be incorporated into the breakseal. The breakseal can also include a flat on an outer perimeter that may serve as a gate for injection molding, so that any gate vestige from the molding process will not protrude beyond the outer diameter of the breakseal to cause unwanted interference between the breakseal and the mating connection.
摘要:
A primary packaging for storage and/or administration of medical or pharmaceutical compounds includes a container that has a predetermined filling volume for receiving a medical or pharmaceutical compound. The container is permanently closed at a first end and has an integrally formed, circumferential flange portion at an open second end. The container has a cylindrical barrel that extends between the first end and the flange portion such that the barrel has an inner diameter and outer diameter corresponding to that of a standardized syringe for a nominal volume of the standardized syringe corresponding to the predetermined filling volume. Furthermore, a cross-sectional shape of the flange portion corresponds to the cross-sectional shape of a flange of a standardized vial. The primary packaging also includes a closure element that is adapted to fit tightly on the flange portion and into the barrel for sealing the open second end of the container.
摘要:
Storage containers for storing fluids are generally discussed herein with particular discussions on storage containers having a rubber septum for port access. Aspects of the present invention further include provisions for a gasket to displace an internal space between a cap and a nozzle of a storage container to minimize or eliminate seepage into the same space.