公开(公告)号：EP3805217A1

公开(公告)日：2021-04-14

申请号：EP19815477.5

申请日：2019-06-06

申请人： Betta Pharmaceuticals Co., Ltd

发明人： WU, Hao ,  GU, Wei ,  TANG, Xiaojing ,  WANG, Wei ,  ZHAN, Bo ,  FENG, Dongjie ,  KE, Yongxin ,  CHEN, Zhongyan ,  SHEN, Yifei ,  WU, Wenmao ,  ZHAO, Xintao ,  LAN, Hong ,  WANG, Jiabing ,  DING, Lieming

IPC分类号： C07D413/04 ,  C07D417/04 ,  A61P35/00 ,  A61K31/506 ,  A61K31/4439 ,  A61K31/496 ,  A61K31/5377

摘要： Disclosed are a compound (as shown in formula I) as an extracellular signal-regulated kinase (ERK) inhibitor, a pharmaceutical composition thereof, a preparation method therefor, and use thereof in treating ERK-mediated diseases. Said compound plays a role by regulating a plurality of processes such as cell proliferation, apoptosis, migration and angiogenesis.