公开(公告)号：EP2920209A1

公开(公告)日：2015-09-23

申请号：EP13789492.9

申请日：2013-11-12

申请人： BioNTech AG ,  Ganymed Pharmaceuticals AG ,  TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH

发明人： SAHIN, Ugur ,  TÜRECI, Özlem ,  STADLER, Christiane ,  HOLLAND, Julia ,  BÄHR-MAHMUD, Hayat ,  BEISSERT, Tim ,  PLUM, Laura ,  LE GALL, Fabrice ,  JENDRETZKI, Arne ,  FIEDLER, Markus

IPC分类号： C07K16/28

摘要： The present invention provides binding agents that contain a binding domain that is specific for CD3 allowing binding to T cells and a binding domain that is specific for a tumor- associated claudin molecule and methods of using these binding agents or nucleic acids encoding therefor for treating cancer.

公开(公告)号：EP3766903A3

公开(公告)日：2021-02-17

申请号：EP20189087.8

申请日：2013-11-12

申请人： BioNTech SE ,  Astellas Pharma Inc. ,  TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH

发明人： SAHIN, Ugur ,  TÜRECI, Özlem ,  STADLER, Christiane ,  HOLLAND, Julia ,  BÄHR-MAHMUD, Hayat ,  BEISSERT, Tim ,  PLUM, Laura ,  LE GALL, Fabrice ,  JENDRETZKI, Arne ,  FIEDLER, Markus

IPC分类号： C07K16/28

摘要： The present disclosure provides binding agents that contain a binding domain that is specific for CD3 allowing binding to T cells and a binding domain that is specific for a tumor-associated claudin molecule and methods of using these binding agents or nucleic acids encoding therefor for treating cancer.

公开(公告)号：EP2920209B1

公开(公告)日：2020-08-05

申请号：EP13789492.9

申请日：2013-11-12

申请人： BioNTech SE ,  Astellas Pharma Inc. ,  TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH

发明人： SAHIN, Ugur ,  TÜRECI, Özlem ,  STADLER, Christiane ,  HOLLAND, Julia ,  BÄHR-MAHMUD, Hayat ,  BEISSERT, Tim ,  PLUM, Laura ,  LE GALL, Fabrice ,  JENDRETZKI, Arne ,  FIEDLER, Markus

IPC分类号： C07K16/28

公开(公告)号：EP3766903A2

公开(公告)日：2021-01-20

申请号：EP20189087.8

申请日：2013-11-12

申请人： BioNTech SE ,  Astellas Pharma Inc. ,  TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH

发明人： SAHIN, Ugur ,  TÜRECI, Özlem ,  STADLER, Christiane ,  HOLLAND, Julia ,  BÄHR-MAHMUD, Hayat ,  BEISSERT, Tim ,  PLUM, Laura ,  LE GALL, Fabrice ,  JENDRETZKI, Arne ,  FIEDLER, Markus

IPC分类号： C07K16/28

摘要： The present disclosure provides binding agents that contain a binding domain that is specific for CD3 allowing binding to T cells and a binding domain that is specific for a tumor-associated claudin molecule and methods of using these binding agents or nucleic acids encoding therefor for treating cancer.

公开(公告)号：EP3515939A1

公开(公告)日：2019-07-31

申请号：EP17776979.1

申请日：2017-09-20

申请人： Biontech AG ,  Astellas Pharma Inc.

发明人： SAHIN, Ugur ,  STADLER, Christiane ,  FISCHER, Leyla ,  JENDRETZKI, Arne ,  TÜRECI, Özlem ,  LE GALL, Fabrice ,  KREUZBERG, Maria

IPC分类号： C07K16/28 ,  A61K39/395 ,  A61P35/00