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1.发明公开
公开(公告)号：EP1515794A1
公开(公告)日：2005-03-23
申请号：EP03760784.3
申请日：2003-06-24
CPC分类号： B01F11/0071 , B01F13/0059 , B01L3/502738 , B01L2200/0605 , B01L2200/0673 , B01L2300/0816 , B01L2400/0442 , B01L2400/06 , B01L2400/0688 , F15C1/04
摘要： The invention relates to hydraulic device (1) produced from one or several components, for example from a support (12) comprising: an operative cavity (3), at least two ducts (41, 42), for example an inlet (41) and outlet (42) for a liquid of interest which communicate with said operative cavity (3), at least two valve bodies (51, 52) with no moving pieces for control of said cavity. The above is characterised in that said device further comprises two trapping chambers (81, 82) for a gas, for example, air, in communication only and respectively with the two ducts (41, 42), by means of two connecting channels (91, 92) respectively, both pertaining to thermal exchange with a heat source (21, 22).
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2.发明公开
公开(公告)号：EP1343586A1
公开(公告)日：2003-09-17
申请号：EP01998402.0
申请日：2001-11-27
IPC分类号： B01L3/00
CPC分类号： B01L3/502761 , B01L3/502723 , B01L2200/0647 , B01L2300/0825 , B01L2400/0406 , B01L2400/043 , B03C1/01 , B03C1/0332 , B03C1/288 , B03C2201/18 , B03C2201/26
摘要： The invention concerns a method for transporting an analyte present in a sample, a method for concentrating an analyte present in a sample, and a device for implementing said methods. The method for transporting an analyte present in a sample consists in preparing a solution A from the sample wherein the analyte is fixed on magnetic particles; introducing solution A in a first container connected via a bottle-neck to a second container; displacing with a magnetic system the analyte fixed on magnetic particles from the first container to the second container via the bottle-neck; the second container being filled with all or part of solution A and/or with another solution.
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公开(公告)号：EP1554565A2
公开(公告)日：2005-07-20
申请号：EP03767940.4
申请日：2003-10-23
IPC分类号： G01N21/64
CPC分类号： G01N21/6452 , G01N21/6428 , G01N2021/6463
摘要： The invention relates to a device (1) which is used to test at least one sample by means of optical luminescence detection. The inventive device comprises one site (3) for receiving the sample, said site being disposed such that the sample can receive a luminescence excitation and emit a luminescence light in an optical guide plane (2) of the device. The device also comprises collection means (7) which are optically connected to the optical guide plane (2) in order to collect the luminescence light. In addition, the device comprises means of sending part of the luminescence light, which is emitted in the optical guide plane but not collected directly by the collection means, towards said collection means (4).
摘要翻译： 本发明涉及用于通过光学发光检测来测试至少一个样品的装置（1）。 本发明的装置包括用于接收样本的一个部位（3），所述部位被布置为使得样本可以接收发光激励并且在装置的光导平面（2）中发射发光光。 该装置还包括光学连接到光导平面（2）以收集发光的收集装置（7）。 此外，该装置包括将发射到光导平面中但不直接由收集装置收集的部分发光光线发送到所述收集装置（4）的装置。
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公开(公告)号：EP1554565B1
公开(公告)日：2015-09-02
申请号：EP03767940.4
申请日：2003-10-23
IPC分类号： G01N21/64
CPC分类号： G01N21/6452 , G01N21/6428 , G01N2021/6463
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公开(公告)号：EP1423539B1
公开(公告)日：2007-10-24
申请号：EP02774913.4
申请日：2002-09-09
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6816 , C12Q1/6823 , C12Q1/6837 , C12Q2545/114
摘要： The invention relates to a method of reading, detecting or quantifying at least one biological reaction, on a support, between either a recognition molecule and a labelled target molecule or between a target molecule and a labelled detection molecule. The inventive method consists essentially in treating the support in physicochemical conditions that allow the following: either the separation of the recognition molecule and the labelled target molecule, or the separation of the target molecule and the labelled detection molecule; and the production of images before and after said treatment which can be used to determine the specific and non-specific bindings between the different molecules. The invention also relates to hybrids and complexes used in the inventive method and to a biochip containing same which is used to carry out said method. The invention is particularly suitable for use in the field of diagnosis.
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6.发明公开
公开(公告)号：EP1682273A1
公开(公告)日：2006-07-26
申请号：EP04805768.1
申请日：2004-10-21
CPC分类号： B01L3/5085 , B01J19/0046 , B01J2219/00317 , B01J2219/00585 , B01J2219/00596 , B01J2219/0065 , B01J2219/00653 , B01J2219/00659 , B01J2219/00677 , B01J2219/00722 , B01J2219/00725 , B01J2219/00743 , B01L3/5027 , B01L3/5088 , B01L2300/0636 , B01L2300/0645 , B01L2300/0816 , B01L2300/0819 , B01L2300/0877 , B01L2300/089 , B01L2400/0487 , C40B40/06 , C40B40/10 , C40B60/14
摘要： The invention concerns a working device (1) comprising working zones. It enables matrices of drops to be obtained on a surface, derived from a liquid of interest (E). It comprises a working box (Bo) provided with means for introducing and extracting (o, s) the liquid into and from the box; a substrate (S) comprising an active surface substantially non wetting with respect to said liquid of interest enclosed in said box.; working zones (Zt) formed separately on said active surface and surrounded each by an edge (b) formed on said active surface, the edges not contiguous to one another with no common boundary therebetween, and having a geometry such that when the liquid of interest is extracted from the box, one drop (g) of the liquid of interest remains trapped by each edge and in contact with said working zone surrounded thereby.
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公开(公告)号：EP1429866A1
公开(公告)日：2004-06-23
申请号：EP02777429.8
申请日：2002-09-12
CPC分类号： B01L3/0244 , G01N1/40 , G01N2035/1046 , Y10T436/25 , Y10T436/2525
摘要： The invention concerns a method for isolating an analyte (1) from an initial sample containing same, on a reactive surface (9) in contact with all or part of the initial sample, characterized in that it comprises the following steps which consist in: 1) forming and/or maintaining a reaction volume entity (2), comprising an internal liquid medium (4), corresponding to all or part of the initial sample, the entity (2) including an interface (5) with an external medium (6), having with the latter a surface tension; 2) applying a temperature difference between at least two thermal points located: a) proximate to and/or b) on the surface and/or c) within said entity (2), said thermal points being respectively different, in terms of temperature and positioning; 3) fixing the analyte (1) on the reactive surface (9), positioned on the path of forced convection generated by the temperature difference.
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公开(公告)号：EP1429866B1
公开(公告)日：2009-06-03
申请号：EP02777429.8
申请日：2002-09-12
CPC分类号： B01L3/0244 , G01N1/40 , G01N2035/1046 , Y10T436/25 , Y10T436/2525
摘要： The invention concerns a method for isolating an analyte (1) from an initial sample containing same, on a reactive surface (9) in contact with all or part of the initial sample, characterized in that it comprises the following steps which consist in: 1) forming and/or maintaining a reaction volume entity (2), comprising an internal liquid medium (4), corresponding to all or part of the initial sample, the entity (2) including an interface (5) with an external medium (6), having with the latter a surface tension; 2) applying a temperature difference between at least two thermal points located: a) proximate to and/or b) on the surface and/or c) within said entity (2), said thermal points being respectively different, in terms of temperature and positioning; 3) fixing the analyte (1) on the reactive surface (9), positioned on the path of forced convection generated by the temperature difference.
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公开(公告)号：EP1706509A1
公开(公告)日：2006-10-04
申请号：EP04816604.5
申请日：2004-12-23
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6837 , C12Q2545/101 , C12Q2545/113
摘要： The invention relates to an analytical chip for at least one analyte, said chip comprising at least one analysis site, which permits the recognition and specific immobilisation of the analyte and a reference scale (G), comprising several reference sites each arranged on said chip in a given manner and independent of each other, each reference site of said scale comprising a reference probe molecule (MSE) fixed to the surface thereof in a given proportion (P) different and known for each site with relation to the other reference sites of said scale, said molecule permitting the recognition and specific hybridisation to a given target reference molecule and/or a neutral oligonucleotide molecule (MN), incapable of recognition and hybridisation with said MSE, said molecules being both incapable of fixing said analyte(s). The method comprises the use of said chip with the reference scale thereof for analysis of said at least one analyte.
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公开(公告)号：EP1216411B1
公开(公告)日：2009-12-30
申请号：EP00966234.7
申请日：2000-09-29
CPC分类号： G01N21/171 , C12Q1/6816 , C12Q2527/101
摘要： The invention concerns a method for detecting without marking a molecular recognition reaction, and a device for implementing said method. The invention concerns the general field of detection and analysis of a molecular recognition between a first molecule and a second molecule, for instance in molecular biology. The inventive method comprises the detection of molecular recognition using a photothermal method, for example a thermal lens microscope.
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