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1.发明公开
公开(公告)号：EP1515794A1
公开(公告)日：2005-03-23
申请号：EP03760784.3
申请日：2003-06-24
CPC分类号： B01F11/0071 , B01F13/0059 , B01L3/502738 , B01L2200/0605 , B01L2200/0673 , B01L2300/0816 , B01L2400/0442 , B01L2400/06 , B01L2400/0688 , F15C1/04
摘要： The invention relates to hydraulic device (1) produced from one or several components, for example from a support (12) comprising: an operative cavity (3), at least two ducts (41, 42), for example an inlet (41) and outlet (42) for a liquid of interest which communicate with said operative cavity (3), at least two valve bodies (51, 52) with no moving pieces for control of said cavity. The above is characterised in that said device further comprises two trapping chambers (81, 82) for a gas, for example, air, in communication only and respectively with the two ducts (41, 42), by means of two connecting channels (91, 92) respectively, both pertaining to thermal exchange with a heat source (21, 22).
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2.发明公开
公开(公告)号：EP1356303A1
公开(公告)日：2003-10-29
申请号：EP02700414.2
申请日：2002-01-25
IPC分类号： G01N35/00
CPC分类号： G01N35/00009 , G01N2035/00237 , G01N2035/1037 , Y10T436/11 , Y10T436/110833 , Y10T436/113332 , Y10T436/2575
摘要： The invention concerns the performing, in continuous flow, of a biological, chemical or biochemical protocol on substances to be analysed, comprising several steps which consists in: in causing a mobile analysis support (11) comprising means (12) for receiving substances to be analysed and reagents to move past; implementing the steps of the protocol on the substances as the mobile analysis support (11) moves past.
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公开(公告)号：EP1753535A1
公开(公告)日：2007-02-21
申请号：EP05776379.9
申请日：2005-06-01
发明人： SARRUT, Nicolas , JEANSON, Hubert
CPC分类号： B01D17/06 , B01D17/045 , B03C11/00 , B03C2201/02
摘要： The invention relates to an active method for decanting the dispersed phase in the continuous phase of an emulsion. According to said method, the repulsive forces created by an electric field are used on the drops constituting the dispersed phase. The electric field (E) scans the reservoir (4) containing the emulsion, enabling the dispersed phase to be concentrated in a determined region (26) of the reservoir (4), for the recovery and/or analysis of the same. The invention also relates to a device (1) for implementing the inventive method.
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4.发明授权
公开(公告)号：EP1567269B1
公开(公告)日：2007-01-03
申请号：EP03789521.6
申请日：2003-11-27
发明人： SARRUT, Nicolas
CPC分类号： B01F13/0076 , B01F13/0093 , B01F2005/0031 , B01J19/0093 , B01J2219/00783 , B01J2219/00853 , B01J2219/00889 , B01L3/502776 , B01L2200/0636 , B01L2400/0415
摘要： The invention concerns a microfluidic device (1) comprising at least one micro-channel delimited by lower (2), lateral (4) and upper (5) walls and designed to contain at least one liquid (6) and at least one fluid (7) non-miscible with the liquid (6). The microfluidic device comprises means for stabilizing the interface between the liquid and the fluid. The stabilizing means include at least one electrode (9) arranged on at least one part of a first wall of the micro-channel, over the entire length thereof and at least one counter-electrode (10) arranged over the entire length of the micro-channel, on at least one part of a second wall, arranged opposite the electrode. The electrode (9) and the counter-electrode (10) are preferably respectively arranged on the micro-channel lower (2) and upper (5) walls.
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公开(公告)号：EP1714300B1
公开(公告)日：2009-10-28
申请号：EP04805818.4
申请日：2004-11-09
发明人： SARRUT, Nicolas
CPC分类号： H01J49/165 , B05B5/0255 , G01N35/1016 , Y10T137/8242 , Y10T137/8326
摘要： The invention relates to a microfluidic device comprising a microfluidic chip (10) which is assembled to an electrospray structure (1), said microfluidic chip being equipped with a microfluidic channel (11) which opens onto an area of the surface of the chip by means of an outlet (12). The electrospray structure consists of at least one flat, thin point (3) comprising a capillary gap (4) which extends to the end (5) of the point such as to form a port for the discharge of the liquid to be sprayed. Moreover, the electrospray is disposed on the surface of the microfluidic chip such that the point (3) is cantilevered in relation to the chip (10) and such that the outlet (12) of the microfluidic channel opens into the capillary gap (4) of the point. The microfluidic device also comprises means for applying an electrospray voltage to the liquid to be sprayed.
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6.发明授权
公开(公告)号：EP1356303B1
公开(公告)日：2004-09-15
申请号：EP02700414.2
申请日：2002-01-25
IPC分类号： G01N35/00
CPC分类号： G01N35/00009 , G01N2035/00237 , G01N2035/1037 , Y10T436/11 , Y10T436/110833 , Y10T436/113332 , Y10T436/2575
摘要： The invention concerns the performing, in continuous flow, of a biological, chemical or biochemical protocol on substances to be analysed, comprising several steps which consists in: in causing a mobile analysis support (11) comprising means (12) for receiving substances to be analysed and reagents to move past; implementing the steps of the protocol on the substances as the mobile analysis support (11) moves past.
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7.发明公开
公开(公告)号：EP1868697A1
公开(公告)日：2007-12-26
申请号：EP06743643.6
申请日：2006-04-06
CPC分类号： B01D11/04 , B01D11/0496
摘要： The invention concerns a method for extracting at least one chemical or biological compound from a liquid phase comprising at least one functionalized ionic liquid, via a liquid extracting fluid (F) which is miscible with said ionic liquid(s), and a microfluidic system (10) for implementing said method. The inventive extraction method includes moving, on one surface (12) of a microfluidic system (19), at least one microdrop (14) of said liquid phase into an extraction solution (20) which comprises said extracting fluid and which is localized on said surface to obtain in output of said solution, under the effect of an electric field, an extract (E) moving away from said surface which is rich in extracting fluid and enriched in said or at least one of said compound(s), and a raffinate (R) moving on said surface which is rich in ionic liquid(s) and deleted in said or one of said compound(s).
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公开(公告)号：EP1714300A1
公开(公告)日：2006-10-25
申请号：EP04805818.4
申请日：2004-11-09
发明人： SARRUT, Nicolas
CPC分类号： H01J49/165 , B05B5/0255 , G01N35/1016 , Y10T137/8242 , Y10T137/8326
摘要： The invention relates to a microfluidic device comprising a microfluidic chip (10) which is assembled to an electrospray structure (1), said microfluidic chip being equipped with a microfluidic channel (11) which opens onto an area of the surface of the chip by means of an outlet (12). The electrospray structure consists of at least one flat, thin point (3) comprising a capillary gap (4) which extends to the end (5) of the point such as to form a port for the discharge of the liquid to be sprayed. Moreover, the electrospray is disposed on the surface of the microfluidic chip such that the point (3) is cantilevered in relation to the chip (10) and such that the outlet (12) of the microfluidic channel opens into the capillary gap (4) of the point. The microfluidic device also comprises means for applying an electrospray voltage to the liquid to be sprayed.
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9.发明公开
公开(公告)号：EP1711955A1
公开(公告)日：2006-10-18
申请号：EP05717692.7
申请日：2005-01-28
CPC分类号： H01J49/04 , B01L3/502707 , B01L2300/0816 , B01L2300/0867
摘要： The invention relates to a lab-on-a-chip comprising a fluidic system which is provided in a substrate, a fluid inlet which is connected to the fluidic system and a fluid outlet which is connected to the fluidic system. The aforementioned substrate comprises a plane layer (53) containing the fluidic system and an electrospray nozzle (65), said electrospray nozzle overhanging the rest of the substrate (51, 52). Moreover, the electrospray nozzle comprises a channel (64) having one end which is connected to the fluidic system and another end which forms the above-mentioned fluid outlet, said channel being equipped with electric conduction means (59) forming at least one electrode.
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10.发明公开
公开(公告)号：EP1567269A1
公开(公告)日：2005-08-31
申请号：EP03789521.6
申请日：2003-11-27
发明人： SARRUT, Nicolas
CPC分类号： B01F13/0076 , B01F13/0093 , B01F2005/0031 , B01J19/0093 , B01J2219/00783 , B01J2219/00853 , B01J2219/00889 , B01L3/502776 , B01L2200/0636 , B01L2400/0415
摘要： The invention concerns a microfluidic device (1) comprising at least one micro-channel delimited by lower (2), lateral (4) and upper (5) walls and designed to contain at least one liquid (6) and at least one fluid (7) non-miscible with the liquid (6). The microfluidic device comprises means for stabilizing the interface between the liquid and the fluid. The stabilizing means include at least one electrode (9) arranged on at least one part of a first wall of the micro-channel, over the entire length thereof and at least one counter-electrode (10) arranged over the entire length of the micro-channel, on at least one part of a second wall, arranged opposite the electrode. The electrode (9) and the counter-electrode (10) are preferably respectively arranged on the micro-channel lower (2) and upper (5) walls.
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