公开(公告)号：EP2023874A2

公开(公告)日：2009-02-18

申请号：EP07809331.7

申请日：2007-06-04

申请人： Bioseek, Inc.

发明人： KUNKEL, Eric J. ,  HYTOPOULOS, Evangelos ,  PLAVEC, Ivan

IPC分类号： A61F13/00

CPC分类号： C12Q1/02 ,  A61K31/13 ,  A61K31/135 ,  A61K31/4706 ,  A61K31/496 ,  A61K31/517 ,  A61K31/519 ,  A61K31/565 ,  A61K45/06 ,  A61L31/16 ,  G01N33/5061 ,  G01N33/5064 ,  G01N2800/323

摘要： Agents that inhibit or prevent restenosis are identified by assaying test agents in a battery of assays to measure the effect of the test agent on cell proliferation, thrombosis, tissue modeling, and inflammation. Treatment for restenosis is provided using compositions of the invention.

摘要翻译： 抑制或预防再狭窄的药剂通过在一系列测定中测试测试药剂来鉴定，以测量测试药剂对细胞增殖，血栓形成，组织建模和炎症的作用。 使用本发明的组合物提供再狭窄治疗。

公开(公告)号：EP1625394A2

公开(公告)日：2006-02-15

申请号：EP04760172.9

申请日：2004-04-23

申请人： Bioseek, Inc.

发明人： HYTOPOULOS, Evangelos

IPC分类号： G01N33/48

CPC分类号： G06F19/24 ,  G01N33/5023 ,  G01N33/5041 ,  G06F19/12 ,  G06F19/18 ,  G06F19/20

摘要： Methods are provided for evaluating biological dataset profiles, where datasets comprising information for multiple cellular parameters are compared and identified. A typical dataset comprises readouts from multiple cellular parameters resulting from exposure of cells to biological factors in the absence or presence of a candidate agent. For analysis of multiple context-defined systems, the output data from multiple systems may be concatenated.