公开(公告)号：EP3190409A1

公开(公告)日：2017-07-12

申请号：EP17150390.7

申请日：2017-01-05

申请人： Board Of Regents Of the University Of Texas System

发明人： DASGUPTA, Purnendu K. ,  SHELOR, Charles Phillip ,  LIAO, Hongzhu

IPC分类号： G01N30/96 ,  B01D15/36

CPC分类号： G01N30/96 ,  B01D15/24 ,  B01D15/363 ,  B01D15/367 ,  G01N27/44756 ,  G01N2030/965

摘要： A permeative amine/acid introduction device (PAID) is placed after a conventional KOH eluent suppressed conductometric anion chromatography (SCAC) system. The PAID converts the suppressed eluites from the acid form to the corresponding salt. For example, when the analytes are acids, they are converted to the corresponding ammonium salt (NR 2 H + Hex → NR 2 H 2 + + X - ) and allows very weak acids HX (pK a ≥ 7.0) that cannot normally be detected by SCAC to be measured by a second conductivity detector following the PAID. Permeative reagent introduction is dilutionless, can be operated without pumps and provides good mixing with low band dispersion (as small as 30 µL). An exemplary amine is diethylamine (DEA), which was chosen as the amine source due to its low pK b value (pK b 3.0), high vapor pressure, and low toxicity and low odor.

摘要翻译： 在常规的KOH洗脱液抑制电导式阴离子色谱（SCAC）系统之后放置渗透性胺/酸引入装置（PAID）。 PAID将受抑制的洗脱液从酸形式转化为相应的盐。 例如，当分析物为酸时，将它们转化为相应的铵盐（NR2H + Hex→NR2H2 ++ X-），并允许通常不能被SCAC检测到的非常弱的酸HX（pKa≥7.0） 电导率检测器遵循PAID。 渗透性试剂引入是无稀释的，可以在没有泵的情况下运行，并提供低频带分散（小至30μL）的良好混合。 示例性的胺是二乙胺（DEA），由于其低pKb值（pKb 3.0），高蒸气压和低毒性和低气味而被选作胺源。