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公开(公告)号：EP2888256A2
公开(公告)日：2015-07-01
申请号：EP13831105.5
申请日：2013-08-23
发明人： JONES, Philip , DIFRANCESCO, Maria, Emilia , PETROCCHI, Alessia , MARSZALEK, Joe , LIU, Gang , KANG, Zhijun , CARROLL, Christopher, L. , MCAFOOS, Timothy , CZAKO, Barbara
IPC分类号： C07D413/14 , A61K31/496 , A61P35/00
CPC分类号： C07D417/14 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/496 , A61K31/501 , A61K31/5377 , A61K31/541 , A61K45/06 , C07D213/82 , C07D237/24 , C07D401/06 , C07D413/04 , C07D413/14
摘要： The present invention relates to compounds and methods which may be useful as inhibitors of HIF pathway activity for the treatment or prevention of cancer and other hypoxia-mediated diseases.
摘要翻译： 本发明涉及可用作HIF途径活性抑制剂的化合物和方法，用于治疗或预防癌症和其他缺氧介导的疾病。
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公开(公告)号：EP2888255B1
公开(公告)日：2018-07-18
申请号：EP13830374.8
申请日：2013-08-23
发明人： JONES, Philip , DIFRANCESCO, Maria, Emilia , PETROCCHI, Alessia , CARROLL, Christopher, L. , MARSZALEK, Joe , CZAKO, Barbara , JOHNSON, Ryan , THEROFF, Jay
IPC分类号： C07D413/14 , A61K31/497 , A61P35/00 , A61K31/506
CPC分类号： C07D495/04 , A61K31/4245 , A61K31/427 , A61K31/437 , A61K31/4439 , A61K31/454 , A61K31/4545 , A61K31/4709 , A61K31/496 , A61K31/497 , A61K31/506 , A61K31/519 , A61K31/5377 , A61K31/541 , A61K45/06 , C07D405/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14 , C07D471/04 , C07D513/04
摘要： The present invention relates to compounds and methods which may be useful as inhibitors of HIF pathway activity for the treatment or prevention of cancer and other hypoxia-mediated diseases.
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公开(公告)号：EP2888253A2
公开(公告)日：2015-07-01
申请号：EP13830788.9
申请日：2013-08-23
IPC分类号： C07D413/04 , C07D417/14 , A61K31/4245 , A61P35/00
CPC分类号： C07D413/04 , A61K31/4245 , A61K31/454 , A61K31/496 , A61K31/5377 , A61K45/06 , C07D413/14 , C07D417/04 , C07D417/14
摘要： The present invention relates to compounds and methods which may be useful as inhibitors of HIF pathway activity for the treatment or prevention of cancer and other hypoxia-mediated diseases.
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