专利检索 ap:("Board of Regents, The University of Texas System" OR "Monash University" OR "Medicines For Malaria Venture" OR "University of Washington" OR "Glaxosmithkline Investigacion y Desarrollo, S.L.") AND inv:"MARWAHA, Alka" 第 1 页

1.

发明授权
ANTIMALARIAL AGENTS THAT ARE INHIBITORS OF DIHYDROOROTATE DEHYDROGENASE 有权
标题翻译：抗疟疾资源二氢乳清酸脱氢酶抑制剂

公开(公告)号：EP2483274B1

公开(公告)日：2014-10-29

申请号：EP10821105.3

申请日：2010-09-28

申请人： Board of Regents, The University of Texas System , Monash University , MMV Medicines for Malaria Venture , University of Washington , Glaxosmithkline Investigacion y Desarrollo, S.L.

发明人： RATHOD, Pradipsinh, K. , FLOYD, David , BURROWS, Jeremy , MARWAHA, Alka , GUJJAR, Ramesh , COTERON-LOPEZ, Jose , PHILLIPS, Margaret , CHARMAN, Susan, A. , MATTHEWS, David

IPC分类号： C07D487/04 , A61K31/519 , A61P33/06

CPC分类号： C07D487/04

2.

发明公开
ANTIMALARIAL AGENTS THAT ARE INHIBITORS OF DIHYDROOROTATE DEHYDROGENASE 有权
标题翻译：抗疟疾资源二氢乳清酸脱氢酶抑制剂

公开(公告)号：EP2483274A2

公开(公告)日：2012-08-08

申请号：EP10821105.3

申请日：2010-09-28

申请人： Board of Regents, The University of Texas System , Monash University , Medicines For Malaria Venture , University of Washington , Glaxosmithkline Investigacion y Desarrollo, S.L.

发明人： RATHOD, Pradipsinh, K. , FLOYD, David , BURROWS, Jeremy , MARWAHA, Alka , GUJJAR, Ramesh , COTERON-LOPEZ, Jose , PHILLIPS, Margaret , CHARMAN, Susan, A. , MATTHEWS, David

IPC分类号： C07D487/04 , A61K31/519 , A61P33/06

CPC分类号： C07D487/04

摘要： Inhibitors of parasitic dihydroorotate dehydrogenase enzyme (DHOD) are candidate therapeutics for treating malaria. Illustrative of such therapeutic agents include the compound: and a triazolopyrimidine class of compounds that conform to Formula (IX): and their solvates, stereoisomers, tautomers and pharmaceutically acceptable salts.