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1.发明授权1,8-NAPHTHYRIDIN-2(1H)-ONE DERIVATIVES AS CYTOMEGALOVIRUS INHIBITORS 有权1,8-萘啶-2（1H） - 酮衍生物作为抑制剂巨细胞病毒
公开(公告)号：EP2855479B1
公开(公告)日：2016-03-30
申请号：EP13716142.8
申请日：2013-04-03
发明人： BEAULIEU, Pierre Louis , BAILEY, Murray , BILODEAU, François , CARSON, Rebekah , GIROUX, André , GODBOUT, Cédrickx , HUCKE, Oliver , JOLY, Marc-André , LEBLANC, Mélissa , LEPAGE, Olivier , MOREAU, Benoît , NAUD, Julie , POIRIER, Martin , VILLEMURE, Elisia , FADER, Lee
IPC分类号： C07D471/14 , C07D471/22 , C07D491/147 , C07D498/14 , C07D498/22 , C07D519/00 , A61K31/4375 , A61K31/5383 , A61P31/22
CPC分类号： C07D498/22 , A61K31/4375 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/5383 , A61K45/06 , C07D471/14 , C07D471/22 , C07D491/107 , C07D491/147 , C07D498/14 , C07D519/00
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公开(公告)号：EP1673385A1
公开(公告)日：2006-06-28
申请号：EP04761821.0
申请日：2004-09-20
发明人： LLINAS-BRUNET, Montse , BAILEY, Murray , BHARDWAJ, Punit , FORGIONE, Pasquale , GHIRO, Elise , GOUDREAU, Nathalie , HALMOS, Teddy , RANCOURT, Jean
CPC分类号： C07K5/0827 , A61K38/00 , C07K5/0802 , C07K5/0812 , Y02A50/463
摘要： Compounds of formula I: wherein D, R4, R3, L0, L1, L2, R2 and RC are defined herein; or a pharmaceutically acceptable salt thereof, useful as inhibitors of the HCV NS3 protease.
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公开(公告)号：EP1730167B1
公开(公告)日：2011-01-12
申请号：EP05706397.6
申请日：2005-01-18
发明人： LLINAS-BRUNET, Montse , BAILEY, Murray , BHARDWAJ, Punit K. , BILODEAU, François , FORGIONE, Pasquale , GHIRO, Elise , GOUDREAU, Nathalie , HALMOS, Teddy , RANCOURT, Jean
CPC分类号： C07K5/0808 , A61K38/00 , C07K5/0812 , C07K5/0827
摘要： Compounds of formula (I): wherein R1, R2, X, R3, D, and the dotted line b are as defined herein; or a pharmaceutically acceptable salt or ester thereof, are useful as inhibitors of the HCV NS3 protease.
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4.发明授权
公开(公告)号：EP2855472B1
公开(公告)日：2016-09-14
申请号：EP13715588.3
申请日：2013-04-03
发明人： LEPAGE, Olivier , BAILEY, Murray , BEAULIEU, Pierre Louis , BILODEAU, François , CARSON, Rebekah , GIROUX, André , GODBOUT, Cédrickx , MOREAU, Benoît , NAUD, Julie , PARISIEN, Mathieu , POIRIER, Martin , POIRIER, Maude , SURPRENANT, Simon , THIBEAULT, Carl , FADER, Lee
IPC分类号： C07D471/04 , C07D519/00 , A61K31/4375 , A61K31/4985 , A61K31/553 , A61K31/506 , A61K31/5513 , A61K31/497 , A61K31/501 , A61K31/496 , A61P31/22
CPC分类号： C07D471/04 , A61K31/4375 , A61K31/496 , A61K31/4985 , A61K31/501 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/5513 , A61K31/553 , A61K45/06 , C07D519/00 , C12N7/00 , C12N2710/16163
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5.发明公开1,8-NAPHTHYRIDIN-2(1H)-ONE DERIVATIVES AS CYTOMEGALOVIRUS INHIBITORS 有权1,8-萘啶-2（1H） - 酮衍生物作为抑制剂巨细胞病毒
公开(公告)号：EP2855479A2
公开(公告)日：2015-04-08
申请号：EP13716142.8
申请日：2013-04-03
发明人： BEAULIEU, Pierre Louis , BAILEY, Murray , BILODEAU, François , CARSON, Rebekah , GIROUX, André , GODBOUT, Cédrickx , HUCKE, Oliver , JOLY, Marc-André , LEBLANC, Mélissa , LEPAGE, Olivier , MOREAU, Benoît , NAUD, Julie , POIRIER, Martin , VILLEMURE, Elisia , FADER, Lee
IPC分类号： C07D471/14 , C07D471/22 , C07D491/147 , C07D498/14 , C07D498/22 , C07D519/00 , A61K31/4375 , A61K31/5383 , A61P31/22
CPC分类号： C07D498/22 , A61K31/4375 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/5383 , A61K45/06 , C07D471/14 , C07D471/22 , C07D491/107 , C07D491/147 , C07D498/14 , C07D519/00
摘要： Compounds of Formula (I) wherein n, A, R
1 , R
2 , R
3 and R
5 are defined herein, are useful for the treatment of cytomegalovirus disease and/or infection.-
6.发明公开
公开(公告)号：EP2855472A1
公开(公告)日：2015-04-08
申请号：EP13715588.3
申请日：2013-04-03
发明人： LEPAGE, Olivier , BAILEY, Murray , BEAULIEU, Pierre Louis , BILODEAU, François , CARSON, Rebekah , GIROUX, André , GODBOUT, Cédrickx , MOREAU, Benoît , NAUD, Julie , PARISIEN, Mathieu , POIRIER, Martin , POIRIER, Maude , SURPRENANT, Simon , THIBEAULT, Carl , FADER, Lee
IPC分类号： C07D471/04 , C07D519/00 , A61K31/4375 , A61K31/4985 , A61K31/553 , A61K31/506 , A61K31/5513 , A61K31/497 , A61K31/501 , A61K31/496 , A61P31/22
CPC分类号： C07D471/04 , A61K31/4375 , A61K31/496 , A61K31/4985 , A61K31/501 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/5513 , A61K31/553 , A61K45/06 , C07D519/00 , C12N7/00 , C12N2710/16163
摘要： Compounds of Formula (I) wherein n, m, R
1 , R
2 , R
3 , R
4 , R5 and R6 are defined herein, are useful for the treatment of cytomegalovirus disease and/or infection.-
公开(公告)号：EP1673385B1
公开(公告)日：2011-03-02
申请号：EP04761821.0
申请日：2004-09-20
发明人： LLINAS-BRUNET, Montse , BAILEY, Murray , BHARDWAJ, Punit , FORGIONE, Pasquale , GHIRO, Elise , GOUDREAU, Nathalie , HALMOS, Teddy , RANCOURT, Jean
CPC分类号： C07K5/0827 , A61K38/00 , C07K5/0802 , C07K5/0812 , Y02A50/463
摘要： Compounds of formula I: wherein D, R4, R3, L0, L1, L2, R2 and RC are defined herein; or a pharmaceutically acceptable salt thereof, useful as inhibitors of the HCV NS3 protease.
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公开(公告)号：EP1730167A1
公开(公告)日：2006-12-13
申请号：EP05706397.6
申请日：2005-01-18
发明人： LLINAS-BRUNET, Montse , BAILEY, Murray , BHARDWAJ, Punit K. , BILODEAU, François , FORGIONE, Pasquale , GHIRO, Elise , GOUDREAU, Nathalie , HALMOS, Teddy , RANCOURT, Jean
CPC分类号： C07K5/0808 , A61K38/00 , C07K5/0812 , C07K5/0827
摘要： Compounds of formula (I): wherein R1, R2, X, R3, D, and the dotted line b are as defined herein; or a pharmaceutically acceptable salt or ester thereof, are useful as inhibitors of the HCV NS3 protease.
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