公开(公告)号：EP1156769A2

公开(公告)日：2001-11-28

申请号：EP00912465.2

申请日：2000-02-16

申请人： Boehringer Ingelheim International GmbH

发明人： KLADDERS, Heinrich ,  ZIERENBERG, Bernd ,  HOCHRAINER, Dieter ,  EICHER, Joachim ,  HAUSMANN, Matthias ,  WUTTKE, Gilbert ,  SCHYRA, Michael ,  FIOL, Andreas ,  GESER, Johannes

IPC分类号： A61J1/00

CPC分类号： B05B11/0054 ,  A61M15/0065 ,  B05B11/0008 ,  B05B11/0016 ,  B05B11/0021 ,  B05B11/0024 ,  B05B11/0043

摘要： A practically diffusion-tight container which is capable of being stored over long periods of time and with which the liquid does not come into contact with the ambient air is required for withdrawing a liquid in a dosed manner out of the same over a duration of several months. The inventive cartridge is a container which is comprised of three shells and which can consist of a collapsible bag containing the liquid, of a dimensionally stabile container, and of a stiff metal shell. The cartridge can be detachably connected to a withdrawing device. The cartridge can be provided with a micro-opening with which the time for the pressure compensation between the cartridge and the surroundings can be adjusted. The cartridge is suited for aqueous and alcoholic liquids which contain a pharmacologically active ingredient. The liquid in the cartridge is protected against external influences. The cartridge can be used in an atomizer for generating an aerosol which can be inhaled and which is provided for treating illnesses.

公开(公告)号：EP1427538B1

公开(公告)日：2008-07-23

申请号：EP02767393.8

申请日：2002-08-16

申请人： Boehringer Ingelheim International GmbH

发明人： EICHER, Joachim ,  FIOL, Andreas ,  SCHYRA, Michael ,  WUTTKE, Gilbert

IPC分类号： B05B11/00 ,  A61M11/00 ,  A61M15/00 ,  A61M5/30

CPC分类号： B05B11/3091 ,  A61M11/06 ,  A61M15/0065

摘要： The invention relates to a locking-tensioning mechanism for a miniaturised high-pressure generator, the construction of said mechanism being configured only for the volume of liquid that is to be delivered. The volume that is to be delivered by said high-pressure generator can be retroactively modified by adjusting the stop of the elastic part. The basic components of the locking-tensioning mechanism and the high-pressure generator remain unchanged. At least one additional component is provided as a spacer in the form of intermediate rings, stepped pulleys, adjusting screws or adjusting nuts. A continuous helical-sliding gear or a helical-sliding gear that can be adjusted in steps can also be used to adjust a stop of the elastic part. The volume to be delivered can be modified either discontinuously or continuously during the assembly of the locking-tensioning mechanism, or prior to the use of the high-pressure generator, or during the use of said high-pressure generator. The locking-tensioning mechanism for a miniaturised high-pressure generator with a reproducibly adjustable volume, lying in the microlitre range, of liquid to be delivered can be used, for example, in a high-pressure atomiser for producing an aerosol that can be inhaled, or in a needle-free injector for injecting a volume of liquid into animal or vegetable tissue.

摘要翻译： 本发明涉及一种用于小型高压发生器的锁紧张紧机构，所述机构的构造仅被配置用于待输送液体的体积。 由所述高压发生器输送的体积可以通过调节弹性部件的停止而追溯性地修改。 锁紧张紧机构和高压发生器的基本部件保持不变。 提供至少一个附加部件作为中间环，阶梯式滑轮，调节螺钉或调节螺母形式的垫片。 也可以使用连续的螺旋滑动齿轮或可以逐级调整的螺旋滑动齿轮来调整弹性部件的停止。 在锁定张紧机构的组装过程中，或者在使用高压发生器之前，或者在使用所述高压发生器的过程中，可以不连续地或连续地改变要输送的体积。 微型高压发生器的锁紧张紧机构可以重复调节体积，位于微升范围内，用于输送液体，例如可用于高压雾化器，用于生产可吸入的气雾剂 或者在用于将一定体积的液体注入动物或植物组织的无针注射器中。

公开(公告)号：EP1883439A2

公开(公告)日：2008-02-06

申请号：EP06753759.7

申请日：2006-05-22

申请人： Boehringer Ingelheim International GmbH

发明人： VON BRUNN, Timo ,  GOLBERG, Christian ,  THÖMMES, Ralf ,  BOECK, Georg ,  WITTE, Florian ,  FIOL, Andreas

IPC分类号： A61M15/00 ,  B05B11/00 ,  B65D83/14

CPC分类号： A61M15/009 ,  A61M11/007 ,  A61M11/02 ,  A61M15/0026 ,  A61M15/0065 ,  A61M15/0073 ,  A61M15/0081 ,  A61M2205/276 ,  B05B11/0008 ,  B05B11/0054 ,  B05B11/3091

摘要： A nebuliser (1) for a fluid, particularly for medical aerosol treatment is proposed. To allow easier operation and confer improved operational reliability a sealed container (3) holding the fluid is already arranged in the nebuliser when it is supplied and the nebuliser is constructed so that the container is opened inside the nebuliser before or during the first use of the nebuliser. Alternatively, or in addition, the nebuliser is constructed so that the container cannot be replaced and in particular cannot be removed.

摘要翻译： 提出了一种用于流体的雾化器（1），特别是用于医疗气雾剂处理的雾化器（1）。 为了允许更容易的操作并且提供改进的操作可靠性，保持流体的密封容器（3）已经被布置在雾化器中，并且雾化器被构造成使得容器在雾化器的第一次使用之前或期间被打开 雾化器。 可选地或另外地，雾化器被构造成使得容器不能被更换，并且特别是不能被移除。

公开(公告)号：EP1720662A1

公开(公告)日：2006-11-15

申请号：EP05715510.3

申请日：2005-02-24

申请人： Boehringer Ingelheim International GmbH

发明人： WUTTKE, Gilbert ,  KAULMANN, Stefan ,  KUNZE, Hubert ,  FIOL, Andreas ,  ZIERENBERG, Bernd ,  NOEHL, Klaus ,  GESER, Johannes

IPC分类号： B05B11/00

CPC分类号： A61M15/0065 ,  A61M15/008 ,  A61M15/0081 ,  A61M15/0083 ,  A61M15/009 ,  A61M2016/0024 ,  A61M2202/0468 ,  A61M2205/18 ,  A61M2205/3306 ,  A61M2205/3592 ,  A61M2205/52 ,  A61M2205/8206 ,  B05B11/308 ,  B05B11/3091

摘要： The invention relates to an atomizer (1) comprising an insertable container (3) and a monitoring device (20) for counting actuations of the atomizer. The monitoring device is arranged in a detachable housing part (15) and directly records movements of the container during an atomizing step, an air flow in the region of a mouth piece and/or the production of an aerosol, in order to detect an actual discharge of fluid and to count the number of actuations of the atomizer. Preferably, the respective moment in time when the atomizer is actuated is detected and stored in order to improve monitoring and user guidance.

公开(公告)号：EP1720663B1

公开(公告)日：2018-11-14

申请号：EP05715511.1

申请日：2005-02-24

申请人： Boehringer Ingelheim International GmbH

发明人： WUTTKE, Gilbert ,  GOLBERG, Christian ,  KUNZE, Hubert ,  FIOL, Andreas ,  SCHMIEDEL, Guido ,  HAUSMANN, Matthias ,  SCHYRA, Michael ,  GESER, Johannes ,  ZIERENBERG, Bernd

IPC分类号： B05B11/00 ,  A61M11/06 ,  A61M15/00 ,  A61M11/00

CPC分类号： A61M11/06 ,  A61M11/007 ,  A61M15/0065 ,  A61M15/0081 ,  A61M2205/60 ,  A61M2205/6045 ,  B05B11/0054 ,  B05B11/3091

公开(公告)号：EP1720662B8

公开(公告)日：2016-06-01

申请号：EP05715510.3

申请日：2005-02-24

申请人： Boehringer Ingelheim International GmbH

发明人： WUTTKE, Gilbert ,  KAULMANN, Stefan ,  KUNZE, Hubert ,  FIOL, Andreas ,  ZIERENBERG, Bernd ,  NOEHL, Klaus ,  GESER, Johannes

IPC分类号： B05B11/00 ,  A61M15/00 ,  A61M16/00

CPC分类号： A61M15/0065 ,  A61M15/008 ,  A61M15/0081 ,  A61M15/0083 ,  A61M15/009 ,  A61M2016/0024 ,  A61M2202/0468 ,  A61M2205/18 ,  A61M2205/3306 ,  A61M2205/3592 ,  A61M2205/52 ,  A61M2205/8206 ,  B05B11/308 ,  B05B11/3091

公开(公告)号：EP1720663A1

公开(公告)日：2006-11-15

申请号：EP05715511.1

申请日：2005-02-24

申请人： Boehringer Ingelheim International GmbH

发明人： WUTTKE, Gilbert ,  GOLBERG, Christian ,  KUNZE, Hubert ,  FIOL, Andreas ,  SCHMIEDEL, Guido ,  HAUSMANN, Matthias ,  SCHYRA, Michael ,  GESER, Johannes ,  ZIERENBERG, Bernd

IPC分类号： B05B11/00

CPC分类号： A61M11/06 ,  A61M11/007 ,  A61M15/0065 ,  A61M15/0081 ,  A61M2205/60 ,  A61M2205/6045 ,  B05B11/0054 ,  B05B11/3091

摘要： The invention relates to an atomiser (1) for a fluid and a container (3) which can be inserted into the atomiser with the fluid. In order to improve safety during use, the atomiser comprises a first coding means (24), and a second coding means (25) is associated with the container, such that the container can only be used with a suitable code in the atomiser or can be used therewith. Preferably, the code associated with the container comprises a specific identification for the fluid disposed in the container.

摘要翻译： 提出了用于流体的雾化器和容纳可插入雾化器中的流体的容器。 为了提高使用中的安全性，提出了雾化器包括第一编码装置，并且容器与第二编码装置相关联，使得容器只能插入雾化器中或如果代码匹配则与其一起使用。 优选地，与容器相关联的代码包括容纳在容器中的流体的清楚识别。

公开(公告)号：EP3370810A2

公开(公告)日：2018-09-12

申请号：EP16793803.4

申请日：2016-11-03

申请人： Boehringer Ingelheim International GmbH

发明人： EICHER, Joachim ,  MEISENHEIMER, Martin ,  FIOL, Andreas

IPC分类号： A61M11/00 ,  A61M15/00

CPC分类号： A61M15/0073 ,  A61M11/007 ,  A61M15/0065 ,  A61M15/0068 ,  A61M15/0071 ,  A61M15/0081 ,  A61M2205/582 ,  A61M2205/584 ,  B05B15/00 ,  G01D13/06

摘要： A system with a nebulizer as well as a container with a fluid and an indicator device for such a nebulizer are proposed. A check scheme is used for indicating the number of containers already used with the nebulizer or which still can be used with the nebulizer. The indicator device indi¬ cates the number of uses performed or still possible with the current container. The indicator device is adapted to let stepwise appear a color sequence and/or replacement symbol when ap¬ proaching a predetermined number of uses with the container. Further, the indicator device can show markings in braille.

公开(公告)号：EP1720662B1

公开(公告)日：2016-04-13

申请号：EP05715510.3

申请日：2005-02-24

申请人： Boehringer Ingelheim International GmbH

发明人： WUTTKE, Gilbert ,  KAULMANN, Stefan ,  KUNZE, Hubert ,  FIOL, Andreas ,  ZIERENBERG, Bernd ,  NOEHL, Klaus ,  GESER, Johannes

IPC分类号： B05B11/00 ,  A61M15/00 ,  A61M16/00

CPC分类号： A61M15/0065 ,  A61M15/008 ,  A61M15/0081 ,  A61M15/0083 ,  A61M15/009 ,  A61M2016/0024 ,  A61M2202/0468 ,  A61M2205/18 ,  A61M2205/3306 ,  A61M2205/3592 ,  A61M2205/52 ,  A61M2205/8206 ,  B05B11/308 ,  B05B11/3091

公开(公告)号：EP1427538A1

公开(公告)日：2004-06-16

申请号：EP02767393.8

申请日：2002-08-16

申请人： Boehringer Ingelheim International GmbH

发明人： EICHER, Joachim ,  FIOL, Andreas ,  SCHYRA, Michael ,  WUTTKE, Gilbert

IPC分类号： B05B11/00 ,  A61M11/00 ,  A61M15/00 ,  A61M5/30

CPC分类号： B05B11/3091 ,  A61M11/06 ,  A61M15/0065

摘要： The invention relates to a locking-tensioning mechanism for a miniaturised high-pressure generator, the construction of said mechanism being configured only for the volume of liquid that is to be delivered. The volume that is to be delivered by said high-pressure generator can be retroactively modified by adjusting the stop of the elastic part. The basic components of the locking-tensioning mechanism and the high-pressure generator remain unchanged. At least one additional component is provided as a spacer in the form of intermediate rings, stepped pulleys, adjusting screws or adjusting nuts. A continuous helical-sliding gear or a helical-sliding gear that can be adjusted in steps can also be used to adjust a stop of the elastic part. The volume to be delivered can be modified either discontinuously or continuously during the assembly of the locking-tensioning mechanism, or prior to the use of the high-pressure generator, or during the use of said high-pressure generator. The locking-tensioning mechanism for a miniaturised high-pressure generator with a reproducibly adjustable volume, lying in the microlitre range, of liquid to be delivered can be used, for example, in a high-pressure atomiser for producing an aerosol that can be inhaled, or in a needle-free injector for injecting a volume of liquid into animal or vegetable tissue.