-
公开(公告)号：EP2010513A2
公开(公告)日：2009-01-07
申请号：EP07727956.0
申请日：2007-04-11
发明人： RIES, Uwe , SPROLL, Sonja , WERTHMANN, Ulrike , ZOPF, Andreas , HUCHLER, Günther
IPC分类号： C07D401/04
CPC分类号： C07D401/14 , C07D401/04
摘要： The invention relates to the novel crystalline compounds A of general formula (I), wherein A1, A2, A3, X, Y1, Y2, and Y3 are defined as indicated in claim 1, and which are provided in the form of the physiologically acceptable salts thereof with acids, said acids being selected among group B comprising hydrochloric acid, hydrobromic acid, sulfuric acid, phosphoric acid, benzenesulfonic acid, p-toluenesulfonic acid, maleic acid, succinic acid, fumaric acid, D-(-)-tartaric acid, L-(+)-tartaric acid, naphthalene-2-sulfonic acid, and naphthalene-1,5-disulfonic acid, as well as the polymorphs, the respective solvates and hydrates.
-
公开(公告)号：EP2195294A1
公开(公告)日：2010-06-16
申请号：EP08803003.6
申请日：2008-08-12
发明人： PACHUR, Kathrin , GOEPPER, Stefan , HUCHLER, Günther , KONRAD, Michael , MAIER, Kathrin , RALL, Werner , RIES, Uwe Jörg , ZOPF, Andreas
IPC分类号： C07D211/58 , C07D401/04 , C07D401/14 , C07C229/42
CPC分类号： C07D211/58 , C07C229/42 , C07D401/04 , C07D401/14
摘要： The present invention relates to a process for preparing compounds of the general formula (I) in which R1.1, R11.2, R1.3 and R2 are defined as mentioned in the description, the pharmaceutically acceptable salts thereof and the solvates thereof, which can be prepared starting from compounds of the general formula (II) in which R1.1, R1.2 and R1.3 are defined as mentioned in the description.
-
3.发明公开VERFAHREN ZUR HERSTELLUNG VON N-PIPERIDINYL-BENZODIAZEPINEN MIT CGRP-ANTAGONISTISCHEN EIGENSCHAFTEN 审中-公开用于生产N-哌啶基 - 苯二氮CGRP拮抗剂性质
公开(公告)号：EP2057142A2
公开(公告)日：2009-05-13
申请号：EP07802657.2
申请日：2007-08-16
发明人： HUCHLER, Günther , RALL, Werner , RIES, Uwe
IPC分类号： C07D401/04 , C07D401/14
CPC分类号： C07D401/04 , C07C59/52 , C07C59/64 , C07C59/68 , C07C229/42 , C07D401/14
摘要： The present invention relates to a method for preparing compounds of the general formula (I) in which R1 and R2 are as defined in claim 1, their pharmaceutically acceptable salts and the solvates thereof, which can be prepared starting from compounds of the general formula (II) in which R1 is as defined in claim 1.
-
4.发明授权
公开(公告)号：EP2318383B1
公开(公告)日：2013-07-03
申请号：EP09776375.9
申请日：2009-02-13
IPC分类号： C07D295/14
CPC分类号： C07D295/14
-
5.发明公开
公开(公告)号：EP2318383A1
公开(公告)日：2011-05-11
申请号：EP09776375.9
申请日：2009-02-13
IPC分类号： C07D295/14
CPC分类号： C07D295/14
摘要： The present invention relates to a process for preparing compounds of the general formula (I) in which m, n, o, R
1 , R
2 and R
3 are each defined as mentioned below, the enantiomers thereof and the diastereomers thereof, which are particularly suitable for preparing compounds of the general formula (II) in which m, o, R
1 , R
2 , R
3 and R
4 are each defined as mentioned below. The compounds of the general formula (II) possess B1-antagonistic properties.
-
-
-
-
搜索结果
5 条记录 (耗时 0.013 秒)
