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公开(公告)号：EP3743067A1
公开(公告)日：2020-12-02
申请号：EP19700964.0
申请日：2019-01-24
IPC分类号： A61K31/437 , A61K31/4412 , A61K31/4985 , A61K31/519 , A61K31/55 , A61K31/5517 , A61P35/02
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公开(公告)号：EP4219493A1
公开(公告)日：2023-08-02
申请号：EP23156525.0
申请日：2018-12-20
发明人： FRANK, Markus , GILLE, Annika , GOEPPER, Stefan , OSTERMEIER, Markus , SANTAGOSTINO, Marco , WIPPICH, Julian , BAUM, Anke , GMACHL, Michael , HOFMANN, Marco Hans , KOFINK, Christiane , RAMHARTER, Juergen , RUDOLPH, Dorothea Ingrid , SAVARESE, Fabio , STADTMUELLER, Heinz , WUNBERG, Tobias
IPC分类号： C07D471/04 , C07D453/02 , C07D519/00 , A61P35/00 , A61K31/519
摘要： The present invention encompasses compounds of formula (I)
wherein the groups R 1 to R 4 , A and p have the meanings given in the claims and specification, their use as inhibitors of SOS1, pharmaceutical compositions which contain compounds of this kind and their use as medicaments/medical uses, especially as agents for treatment and/or prevention of oncological diseases.-
公开(公告)号：EP3728254A1
公开(公告)日：2020-10-28
申请号：EP18830816.7
申请日：2018-12-20
发明人： RAMHARTER, Juergen , KOFINK, Christiane , STADTMUELLER, Heinz , WUNBERG, Tobias , HOFMANN, Marco Hans , BAUM, Anke , GMACHL, Michael , RUDOLPH, Dorothea Ingrid , SAVARESE, Fabio , OSTERMEIER, Markus , FRANK, Markus , GILLE, Annika , GOEPPER, Stefan , SANTAGOSTINO, Marco , WIPPICH, Julian
IPC分类号： C07D471/04 , C07D453/02 , C07D519/00 , A61P35/00 , A61K31/519
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