-
公开(公告)号：EP1765355A1
公开(公告)日：2007-03-28
申请号：EP05740045.9
申请日：2005-04-18
发明人： BOUYSSOU, Thierry , KONETZKI, Ingo , PESTEL, Sabine , SCHNAPP, Andreas , HOENKE, Christoph , LUSTENBERGER, Philipp , RUDOLF, Klaus , SCHROMM, Kurt , BUETTNER, Frank , HEINE, Claudia , SCHOLLENBERGER, Hermann
IPC分类号： A61K31/538 , A61P11/06
CPC分类号： A61K31/538
摘要： The invention relates to the use of compounds of general formula (1), wherein the radicals R1, R2 and R3 can have the meaning cited in the claims and in the description. The invention also relates to the production of a medicament for treating respiratory tract diseases.
-
公开(公告)号：EP1765355B1
公开(公告)日：2013-03-06
申请号：EP05740045.9
申请日：2005-04-18
发明人： BOUYSSOU, Thierry , KONETZKI, Ingo , PESTEL, Sabine , SCHNAPP, Andreas , HOENKE, Christoph , LUSTENBERGER, Philipp , RUDOLF, Klaus , SCHROMM, Kurt , BUETTNER, Frank , HEINE, Claudia , SCHOLLENBERGER, Hermann
IPC分类号： A61K31/538 , A61P11/06
CPC分类号： A61K31/538
-
3.发明授权
公开(公告)号：EP1562603B3
公开(公告)日：2014-01-08
申请号：EP03778312.3
申请日：2003-11-11
发明人： BOUYSSOU, Thierry , BUETTNER, Frank , KONETZKI, Ingo , PESTEL, Sabine , SCHNAPP, Andreas , SCHOLLENBERGER, Hermann , SCHROMM, Kurt , HEINE, Claudia , RUDOLF, Klaus , LUSTENBERGER, Philipp , HOENKE, Christoph
IPC分类号： A61K31/538 , A61P11/00 , A61K31/535
CPC分类号： A61K31/538 , C07D265/36
-
公开(公告)号：EP2958919A1
公开(公告)日：2015-12-30
申请号：EP13705185.0
申请日：2013-02-21
IPC分类号： C07D475/00 , C07D475/12 , A61K31/519
CPC分类号： C07D487/14 , C07D471/14 , C07D475/00 , C07D475/12 , C07D498/14
摘要： The present invention relates to dihydropteridinones, their use as modulators of γ-secretase and to pharmaceutical compositions containing said compounds. In particular, the present invention relates to compounds which interfere with γ-secretase and/or its substrate and therefore modulate the formation of Αβ peptides.
-
5.发明公开3-HYDROXYMETHYL-4-HYDROXY-PHENYL-DERIVATE ZUR BEHANDLUNG VON ATEMWEGSERKRANKUNGEN 审中-公开3-羟甲基-4-羟基 - 苯基衍生物对呼吸系统疾病的治疗
公开(公告)号：EP1706389A1
公开(公告)日：2006-10-04
申请号：EP05700676.9
申请日：2005-01-04
发明人： BOUYSSOU, Thierry , BUETTNER, Frank , KONETZKI, Ingo , PESTEL, Sabine , SCHNAPP, Andreas , SCHOLLENBERGER, Hermann , SCHROMM, Kurt , HEINE, Claudia
IPC分类号： C07D249/08 , A61K31/4164 , A61P11/00 , A61K31/4196 , C07D233/54
CPC分类号： C07D249/08 , C07D233/64
摘要： The invention relates to the use of compounds of general formula 1 wherein the groups R1, X and Y have the designations cited in the claims and in the description, for producing a medicament for treating COPD (chronic obstructive pulmonary disease). The invention also relates to novel compounds of general formula 1, and to methods for the production thereof.
-
公开(公告)号：EP1594873A1
公开(公告)日：2005-11-16
申请号：EP04708347.2
申请日：2004-02-05
发明人： ANDERSKEWITZ, Ralf , DOLLINGER, Horst , HEINE, Claudia , POUZET, Pascale, Arielle, Jane-Josee , BIRKE, Franz , BOUYSSOU, Thierry
IPC分类号： C07D487/04 , C07D471/14
CPC分类号： C07D487/04 , C07D491/14 , C07D495/14
摘要： The invention relates to the novel compounds of formula (I) or stereoisomers or pharmaceutically acceptable salts thereof, wherein the groups Ar1, Ar2, A, R1, R2, R3, E1, E2, X and n are as defined in the description and claims, which are effective modulators of chemokine activity.
-
公开(公告)号：EP1594873B1
公开(公告)日：2010-12-15
申请号：EP04708347.2
申请日：2004-02-05
发明人： ANDERSKEWITZ, Ralf , DOLLINGER, Horst , HEINE, Claudia , POUZET, Pascale, Arielle, Jane-Josee , BIRKE, Franz , BOUYSSOU, Thierry
IPC分类号： C07D487/04 , C07D471/14
CPC分类号： C07D487/04 , C07D491/14 , C07D495/14
摘要： The invention relates to the novel compounds of formula (I) or stereoisomers or pharmaceutically acceptable salts thereof, wherein the groups Ar1, Ar2, A, R1, R2, R3, E1, E2, X and n are as defined in the description and claims, which are effective modulators of chemokine activity.
摘要翻译： 本发明涉及式（I）的新化合物或其立体异构体或药学上可接受的盐，其中基团Ar1，Ar2，A，R1，R2，R3，E1，E2，X和n如说明书和权利要求书中所定义。 ，它们是趋化因子活性的有效调节剂。
-
公开(公告)号：EP2958919B1
公开(公告)日：2019-05-22
申请号：EP13705185.0
申请日：2013-02-21
IPC分类号： C07D475/00 , C07D475/12 , A61K31/519
-
-
-
-
-
-
-
搜索结果
8 条记录 (耗时 0.024 秒)
