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    System and method for identifying complex patterns of amino acids
    9.
    发明公开
    System and method for identifying complex patterns of amino acids 审中-公开
    系统和Verfahren zur Identifizierung komplexerAminosäurenstrukturen

    公开(公告)号：EP2390804A2

    公开(公告)日：2011-11-30

    申请号：EP11158038.7

    申请日：2005-04-28

    申请人： Bogoch, Samuel ,  Bogoch, Elenore S. ,  Bogoch, Samuel Winston ,  Borsanyi, Anne Elenore

    发明人： Bogoch, Samuel ,  Bogoch, Elenore S. ,  Bogoch, Samuel Winston ,  Borsanyi, Anne Elenore

    IPC分类号： G06F19/00 ,  G06F17/00 ,  G01N33/50 ,  C07K16/10 ,  G06F19/22 ,  G06F19/16

    CPC分类号： G06F19/22

    摘要： A method and system are disclosed for identifying and/or locating complex patterns in an amino acid sequence stored in a computer file of database. According to an aspect of the present invention, techniques are provided to facilitate queries of protein databases. For protein descriptions received in response to the queries, embodiments of the present invention may scan the received protein descriptions to identify and locate Replikin patterns. A Replikin pattern is defined to be a sequence of 7 to about 50 amino acids that include the following three (3) characteristics, each of which may be recognized by an embodiment of the present invention: (1) the sequence has at least one lysine residue located six to ten amino acid residues from a second lysine residue; (2) the sequence has at least one histidine residue; and (3) at least 6% of the amino acids in the sequence are lysine residues.

    摘要翻译： 公开了用于识别和/或定位存储在数据库的计算机文件中的氨基酸序列中的复杂模式的方法和系统。 根据本发明的一个方面，提供了技术来促进蛋白质数据库的查询。 对于响应于查询而接收的蛋白质描述，本发明的实施方案可以扫描接收到的蛋白质描述以识别和定位Replikin模式。 复制素模式被定义为7至约50个氨基酸的序列，其包括以下三（3）个特征，每个特征可以被本发明的实施方案识别：（1）序列具有至少一个赖氨酸 残基位于第二赖氨酸残基6至10个氨基酸残基; （2）序列具有至少一个组氨酸残基; 和（3）序列中至少6％的氨基酸是赖氨酸残基。