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1.发明公开Process for the iodination of aromatic compounds 审中-公开Verfahren zur Iodierung aromatischer Verbindungen
公开(公告)号：EP2243767A1
公开(公告)日：2010-10-27
申请号：EP09158319.5
申请日：2009-04-21
发明人： CITTERIO, Attilio , LATTUADA, Luciano , LEONARDI, Gabriella , UGGERI, Fulvio , VIGNALE, Evelin , VISIGALLI, Massimo
IPC分类号： C07C227/16
CPC分类号： C07C227/16 , C07C229/62
摘要： The present invention relates to a process for the preparation of iodinated anilines; in particular, it relates to a process including the direct iodination of 3,5-disubstituted anilines to the corresponding 3,5-disubstituted-2,4,6-triiodoanilines, which are useful intermediates for the synthesis of x-ray contrast media, and to the preparation of the contrast media themselves.
摘要翻译： 本发明涉及一种制备碘化苯胺的方法; 特别涉及包括将3,5-二取代的苯胺直接碘化为相应的3,5-二取代-2,4,6-三碘苯胺的方法，它们是合成X射线造影剂的有用中间体， 以及造影剂本身的制备。
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公开(公告)号：EP2421819B1
公开(公告)日：2014-03-05
申请号：EP10718104.2
申请日：2010-04-08
申请人： Bracco Imaging S.p.A
发明人： CITTERIO, Attilio , LATTUADA, Luciano , FERRIGATO, Aurelia , FRETTA, Roberta , MAZZON, Roberta , MELI, Gabriele , LEONARDI, Gabriella , UGGERI, Fulvio , VIGNALE, Evelin , VISIGALLI, Massimo
IPC分类号： C07C227/16
CPC分类号： C07C227/16 , C07C229/62
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公开(公告)号：EP2580187B1
公开(公告)日：2015-05-27
申请号：EP11725069.6
申请日：2011-06-09
申请人： Bracco Imaging S.p.A
发明人： CITTERIO, Attilio , BATTISTINI, Elisa , BELNOME, Davide , BUONSANTI, Federica , LATTUADA, Luciano , LEONARDI, Gabriella , UGGERI, Fulvio , VIGNALE, Evelin , VISIGALLI, Massimo
IPC分类号： C07C231/10 , C07C237/46
CPC分类号： C07B39/00 , C07C231/10 , C07C231/12 , C07C231/14 , C07C235/48 , C07C237/46
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公开(公告)号：EP2580187A1
公开(公告)日：2013-04-17
申请号：EP11725069.6
申请日：2011-06-09
申请人： Bracco Imaging S.p.A
发明人： CITTERIO, Attilio , BATTISTINI, Elisa , BELNOME, Davide , BUONSANTI, Federica , LATTUADA, Luciano , LEONARDI, Gabriella , UGGERI, Fulvio , VIGNALE, Evelin , VISIGALLI, Massimo
IPC分类号： C07C231/10 , C07C237/46
CPC分类号： C07B39/00 , C07C231/10 , C07C231/12 , C07C231/14 , C07C235/48 , C07C237/46
摘要： The present invention relates to a process for the preparation of iodinated phenols; in particular; it relates to a process including the direct iodination, with suitably activated iodine, of 3,5-disubstituted phenol compounds to the corresponding 3,5-disubstituted-2,4,6-triiodophenols, which are useful intermediates for the synthesis of x-ray contrast media, and to the preparation of the contrast media themselves.
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公开(公告)号：EP2421819A1
公开(公告)日：2012-02-29
申请号：EP10718104.2
申请日：2010-04-08
申请人： Bracco Imaging S.p.A
发明人： CITTERIO, Attilio , LATTUADA, Luciano , FERRIGATO, Aurelia , FRETTA, Roberta , MAZZON, Roberta , MELI, Gabriele , LEONARDI, Gabriella , UGGERI, Fulvio , VIGNALE, Evelin , VISIGALLI, Massimo
IPC分类号： C07C227/16
CPC分类号： C07C227/16 , C07C229/62
摘要： The present invention relates to a process for the preparation of iodinated anilines; in particular, it relates to a process including the direct iodination, with suitably activated iodine, of 3,5-disubstituted anilines to the corresponding 3,5- disubstituted-2,4,6-triiodoanilines, which are useful intermediates for the synthesis of x-ray contrast media, and to the preparation of the contrast media themselves.
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