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公开(公告)号：EP2960284B1
公开(公告)日：2018-08-01
申请号：EP14745896.2
申请日：2014-01-30
发明人： YUKIMURA, Noriaki , YOSHIZAWA, Takahiro , KODAMA, Kazuhiro , YUASA, Hiroaki , SHIINA, Noriaki , SATO, Takashi , ISHITOBI, Hiroyuki , UENO, Mifuyu , NAKASHIMA, Shinya , ABE, Masaki
IPC分类号： C08L7/00 , B60C1/00 , B60C11/00 , C08K3/00 , C08K5/31 , C08L9/00 , C08K3/04 , C08K5/36 , C08K5/3462 , C08K5/3447 , C08K5/3445
CPC分类号： C08K5/36 , B60C1/00 , B60C1/0016 , B60C11/00 , B60C2200/065 , C08K3/00 , C08K3/04 , C08K5/31 , C08K5/3415 , C08K5/3417 , C08K5/3445 , C08K5/3447 , C08K5/3462 , C08L7/00 , C08L9/00
摘要： The invention provides a rubber composition prepared by mixing, per 100 parts by mass of a rubber component comprising at least 50% by mass of a diene-based rubber, from 20 to 150 parts by mass of a filler, and from 0.05 to 30 parts by mass of a compound A which has a specific guanidine structure and has a functional group reactive with the diene-based rubber. The rubber composition improves both a high elastic modulus and a low tan´. The invention also provides a pneumatic tire using the rubber composition.
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公开(公告)号：EP2960284A1
公开(公告)日：2015-12-30
申请号：EP14745896.2
申请日：2014-01-30
发明人： YUKIMURA, Noriaki , YOSHIZAWA, Takahiro , KODAMA, Kazuhiro , YUASA, Hiroaki , SHIINA, Noriaki , SATO, Takashi , ISHITOBI, Hiroyuki , UENO, Mifuyu , NAKASHIMA, Shinya , ABE, Masaki
CPC分类号： C08K5/36 , B60C1/00 , B60C1/0016 , B60C11/00 , B60C2200/065 , C08K3/00 , C08K3/04 , C08K5/31 , C08K5/3415 , C08K5/3417 , C08K5/3445 , C08K5/3447 , C08K5/3462 , C08L7/00 , C08L9/00
摘要： The invention provides a rubber composition prepared by mixing, per 100 parts by mass of a rubber component comprising at least 50% by mass of a diene-based rubber, from 20 to 150 parts by mass of a filler, and from 0.05 to 30 parts by mass of a compound A which has a specific guanidine structure and has a functional group reactive with the diene-based rubber. The rubber composition improves both a high elastic modulus and a low tanδ. The invention also provides a pneumatic tire using the rubber composition.
摘要翻译： 本发明提供了一种橡胶组合物，其通过将基于100质量份的包含至少50质量％二烯烃系橡胶的橡胶组分，20至150质量份填料和0.05至30质量份 的具有特定的胍结构且具有与二烯系橡胶反应的官能团的化合物A. 橡胶组合物改善了高弹性模量和低tanδ。 本发明还提供使用该橡胶组合物的充气轮胎。
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公开(公告)号：EP2952541A1
公开(公告)日：2015-12-09
申请号：EP14746370.7
申请日：2014-01-30
发明人： YUKIMURA, Noriaki , YOSHIZAWA, Takahiro , KODAMA, Kazuhiro , YUASA, Hiroaki , SHIINA, Noriaki , SATO, Takashi , ISHITOBI, Hiroyuki , UENO, Mifuyu , NAKASHIMA, Shinya , ABE, Masaki
CPC分类号： C08F136/08 , B60C1/00 , C08K5/29 , C08K5/3447 , C08K5/3725 , C08L7/00 , C08L9/00 , C08L21/00
摘要： The invention provides a rubber composition prepared by mixing, per 100 parts by mass of the rubber component comprising at least 50% by mass of a diene-based rubber, from 20 to 150 parts by mass of a filler, and from 0.05 to 30 parts by mass of a compound A which has a specific amidine structure and has a functional group reactive with the diene-based rubber. The rubber composition improves both a high elastic modulus and a low tanδ. The invention also provides a pneumatic tire using the rubber composition.
摘要翻译： 本发明提供了一种橡胶组合物，其通过将基于100质量份的包含至少50质量％的二烯系橡胶的橡胶组分，20至150质量份的填料和0.05至30质量份 的具有特定脒结构且具有与二烯系橡胶反应的官能团的化合物A. 橡胶组合物改善了高弹性模量和低tanδ。 本发明还提供使用该橡胶组合物的充气轮胎。
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公开(公告)号：EP3269747A1
公开(公告)日：2018-01-17
申请号：EP16761755.4
申请日：2016-03-08
发明人： TANAKA, Masaru , ISHITOBI, Hiroyuki
IPC分类号： C08F297/00 , A61L29/00 , A61L31/00
CPC分类号： A61L33/064 , A61L29/00 , A61L31/00 , A61L31/10 , A61L31/16 , A61L2300/42 , A61P7/02 , C08F293/005 , C08F297/00
摘要： The present invention addresses the problem of providing a block copolymer that has excellent adhesion to a base material and that can impart excellent antithrombogenicity to the base material surface, and providing a medical device comprising the block copolymer. The block copolymer according to the present invention comprises an A block and a B block. The A block is capable of containing intermediate water. The B block is more hydrophobic than the A block. The medical device according to the present invention is obtained by coating a medical device with an antithrombotic coating agent containing the block copolymer.
摘要翻译： 本发明解决了提供一种嵌段共聚物的问题，该嵌段共聚物对基材具有优异的粘合性，并且可以赋予基材表面优异的抗血栓形成性，并且提供包含该嵌段共聚物的医疗装置。 根据本发明的嵌段共聚物包含A嵌段和B嵌段。 A区块能够容纳中间水。 B嵌段比A嵌段更具疏水性。 根据本发明的医疗装置通过用包含嵌段共聚物的抗血栓涂层剂涂布医疗装置而获得。
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5.发明公开IgA-BINDING PEPTIDE AND PURIFICATION OF IgA THEREBY 审中-公开IGA-BINDENDES PEPTID UND IGA-REINIGUNG DAMIT
公开(公告)号：EP2787079A1
公开(公告)日：2014-10-08
申请号：EP12852729.8
申请日：2012-11-29
发明人： ITO, Yuji , ITO, Osamu , OOZONO, Shinji , ISHITOBI, Hiroyuki
CPC分类号： C07K7/08 , C07K1/22 , C07K16/065 , C07K17/00 , C07K2319/00 , G01N33/6854
摘要： This invention provides a peptide that comprises an amino acid sequence consisting of 14 to 18 amino acid residues represented by Formula (I) and is capable of binding to human IgA:
H-(X 1 )-V-C-L-S-Y-R-(X 2 )-(X 3 )-G-(X 4 )-P-(X 5 )-C-(X 6 )-(X 7 )-(X 8 ) (I) (SEQ ID NO: 1)
wherein each X is independently selected from among the following: X 1 represents a Gln residue or a Met residue; X 2 and X 3 each independently represent an arbitrary amino acid residue other than Cys or either or both thereof are deleted; X 4 represents an Arg residue or a Gln residue; X 5 represents a Val residue or a Thr residue; X 6 represents a Phe residue or a Tyr residue; X 7 represents a Ser residue or is null; and X 8 represents a Leu residue, a Thr residue, or is null, provided that, when X 1 represents a Met residue, X 7 represents a Ser residue or is null, and X 8 is null. The invention also provides a method for purifying or analyzing human IgA using such peptide.摘要翻译： 本发明提供一种肽，其包含由式（I）表示的14至18个氨基酸残基并能够结合人IgA的氨基酸序列：€ƒ€€ƒ€ƒ€ƒ€ƒH - （X 1）-VCLSYR-（X 2） - （X 3）-G-（X 4）-P-（X 5）-C-（X 6） - （X 7） - （X 8） （I）（I）（SEQ ID NO：1），其中每个X独立地选自以下各项：X 1表示Gln残基或Met残基; X 2和X 3各自独立地表示除Cys之外的任意氨基酸残基，或者两者之一或两者都被缺失; X 4表示Arg残基或Gln残基; X 5表示Val残基或Thr残基; X 6表示Phe残基或Tyr残基; X 7表示Ser残基或无效; 并且X 8表示Leu残基，Thr残基或为空，条件是当X 1表示Met残基时，X 7表示Ser残基或为空，X 8为空。 本发明还提供了使用这种肽纯化或分析人IgA的方法。
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