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1.发明公开
公开(公告)号：EP2271650A1
公开(公告)日：2011-01-12
申请号：EP09733949.3
申请日：2009-04-20
发明人： COOK II, James, H. , MCDONALD, Ivar, M. , KING, Dalton , OLSON, Richard, E. , WANG, Nenghui , IWUAGWU, Christiana, I. , ZUSI, F., Christopher , MACOR, John, E.
IPC分类号： C07D498/20 , A61K31/439 , A61P25/28
CPC分类号： C07D498/20 , C07D519/00
摘要： The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic α 7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.
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2.发明公开QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS 有权CHINUKLIDINE衍生物如α-7尼古丁乙酰胆碱受体配体
公开(公告)号：EP2493892A1
公开(公告)日：2012-09-05
申请号：EP09744572.0
申请日：2009-10-29
发明人： COOK II, James H. , MCDONALD, Ivar, M. , KING, Dalton , OLSON, Richard, E. , WANG, Nenghui , IWUAGWU, Christiana, I. , ZUSI, F.,Christopher , MACOR, John, E.
IPC分类号： C07D498/20 , A61K31/439 , A61P25/28
CPC分类号： C07D498/20
摘要： The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic 7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.
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3.发明授权
公开(公告)号：EP2271650B1
公开(公告)日：2015-09-16
申请号：EP09733949.3
申请日：2009-04-20
发明人： COOK II, James, H. , MCDONALD, Ivar, M. , KING, Dalton , OLSON, Richard, E. , WANG, Nenghui , IWUAGWU, Christiana, I. , ZUSI, F., Christopher , MACOR, John, E.
IPC分类号： C07D498/20 , C07D519/00 , A61K31/439 , A61P25/28
CPC分类号： C07D498/20 , C07D519/00
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4.发明授权QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS 有权CHINUKLIDINE衍生物如α-7尼古丁乙酰胆碱受体配体
公开(公告)号：EP2493892B1
公开(公告)日：2015-07-01
申请号：EP09744572.0
申请日：2009-10-29
发明人： COOK II, James H. , MCDONALD, Ivar, M. , KING, Dalton , OLSON, Richard, E. , WANG, Nenghui , IWUAGWU, Christiana, I. , ZUSI, F.,Christopher , MACOR, John, E.
IPC分类号： C07D498/20 , A61K31/439 , A61P25/28
CPC分类号： C07D498/20
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