公开(公告)号：EP0484856A2

公开(公告)日：1992-05-13

申请号：EP91118770.6

申请日：1991-11-04

申请人： Bristol-Myers Squibb Company

发明人： Saitoh, Kyoichiro ,  Miyaki, Takeo ,  Yamamoto, Haruaki ,  Oda, Nahomi

IPC分类号： C07D491/044 ,  C12P17/18 ,  A61K31/445

CPC分类号： C07D491/04 ,  C12P17/18 ,  C12R1/29

摘要： The novel antitumor antibiotic of formula (I) designated herein as dynemicin C is produced by fermentation of Micromonospora chersina M956-1 mutant F1085 (ATCC-55077). Dynemicin C and its triacetate derivative possess antibacterial and antifungal activity and also inhibit the growth of mammalian tumors.

摘要翻译： 本文命名为Dynemicin C的式（I）抗新药抗生素由Micromonospora chersina M956-1突变体F1085（ATCC-55077）的发酵产生。 Dynemicin C及其三醋酸酯衍生物具有抗菌和抗真菌活性，也抑制哺乳动物肿瘤的生长。

公开(公告)号：EP0484856A3

公开(公告)日：1992-07-01

申请号：EP91118770.6

申请日：1991-11-04

申请人： Bristol-Myers Squibb Company

发明人： Saitoh, Kyoichiro ,  Miyaki, Takeo ,  Yamamoto, Haruaki ,  Oda, Nahomi

IPC分类号： C07D491/044 ,  C12P17/18 ,  A61K31/445

CPC分类号： C07D491/04 ,  C12P17/18 ,  C12R1/29

摘要： The novel antitumor antibiotic of formula (I) designated herein as dynemicin C is produced by fermentation of Micromonospora chersina M956-1 mutant F1085 (ATCC-55077). Dynemicin C and its triacetate derivative possess antibacterial and antifungal activity and also inhibit the growth of mammalian tumors.