专利检索 ap:("Bristol-Myers Squibb Company" OR "JANSSEN Pharmaceutica NV") AND inv:"SINGH, Amartjit" 第 1 页

1.

发明公开
NOVEL SYNTHETIC OPTIONS TOWARDS THE MANUFACTURE OF (6R,10S)-10- {4-[5-CHLORO-2-(4-CHLORO-1H-1,2,3-TRIAZOL-1-YL)PHENYL]-6-OXO-1(6H)- PYRIMIDINYL}- 1-(DIFLUOROMETHYL)-6-METHYL-1,4,7,8,9,10-HEXAHYDRO-11,15 -(METHENO)PYRAZOLO [4,3-B] [1,7] DIAZACYCLOTETRADECIN-5(6H)-ONE 审中-公开

公开(公告)号：EP4234555A3

公开(公告)日：2024-01-03

申请号：EP23169596.6

申请日：2020-04-10

申请人： Bristol-Myers Squibb Company , JANSSEN Pharmaceutica NV

发明人： CUNIERE, Nicolas , FAN, Yu , KOLOTUCHIN, Sergei , MUKHERJEE, Subha , SIMMONS, Eric M. , SINGH, Amartjit , WEI, Carolyn S. , XIAO, Yi , YUAN, Changxia , ZHENG, Bin , WAGSCHAL, Simon Albert , BROGGINI, Diego Fernando Domenico , CAO, Duy Chi Trung , CHERNICHENKO, Kostiantyn , LEMAIRE, Sébastien François Emmanuel , BEN HAIM, Cyril

IPC分类号： C07D471/18 , C07D401/04 , C07D213/61

摘要： Highly efficient methods are provided for preparing key intermediates in the synthesis of Compound (I), which are broadly applicable and can provide selected components having a variety of substituents groups.

2.

发明公开
NOVEL SYNTHETIC OPTIONS TOWARDS THE MANUFACTURE OF (6R,10S)-10- {4-[5-CHLORO-2-(4-CHLORO-1H-1,2,3-TRIAZOL-1-YL)PHENYL]-6-OXO-1(6H)- PYRIMIDINYL}- 1-(DIFLUOROMETHYL)-6-METHYL-1,4,7,8,9,10-HEXAHYDRO-11,15 -(METHENO)PYRAZOLO [4,3-B] [1,7] DIAZACYCLOTETRADECIN-5(6H)-ONE 审中-公开

公开(公告)号：EP4234555A2

公开(公告)日：2023-08-30

申请号：EP23169596.6

申请日：2020-04-10

申请人： Bristol-Myers Squibb Company , JANSSEN Pharmaceutica NV

发明人： CUNIERE, Nicolas , FAN, Yu , KOLOTUCHIN, Sergei , MUKHERJEE, Subha , SIMMONS, Eric M. , SINGH, Amartjit , WEI, Carolyn S. , XIAO, Yi , YUAN, Changxia , ZHENG, Bin , WAGSCHAL, Simon Albert , BROGGINI, Diego Fernando Domenico , CAO, Duy Chi Trung , CHERNICHENKO, Kostiantyn , LEMAIRE, Sébastien François Emmanuel , BEN HAIM, Cyril

IPC分类号： C07D471/18

摘要： Highly efficient methods are provided for preparing key intermediates in the synthesis of Compound (I), which are broadly applicable and can provide selected components having a variety of substituents groups.