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公开(公告)号:EP2266989B1
公开(公告)日:2015-09-02
申请号:EP09754921.6
申请日:2009-03-31
发明人: AHN, Sung Oh , PARK, Chan Hee , IM, Jun Hwan , LEE, Soon Ok , LEE, Kyoung June , CHO, Seong Wook , KO, Kwang Seok , HAN, Sun Young , LEE, Won Il
IPC分类号: C07D498/04 , A61K31/4375 , A61P3/00 , A61P9/12
CPC分类号: C07D498/04
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公开(公告)号:EP3004057A1
公开(公告)日:2016-04-13
申请号:EP14806807.5
申请日:2014-06-03
发明人: PARK, Chan Hee , LEE, Sang Hwi , IM, Junhwan , LEE, Soon Ok , KIM, Hoe Moon , MOON, Sung Hyun , KIM, Seunghee , KIM, Jongmin , KO, Kwang Seok , CHOI, Bu Young , KIM, Byungho
IPC分类号: C07D209/42 , A61K31/404 , A61P35/00 , A61P29/00
CPC分类号: C07D495/04 , C07D209/42 , C07D277/68 , C07D307/86 , C07D333/68 , C07D333/70 , C07D401/12 , C07D403/12 , C07D409/12 , C07D413/12 , C07D417/04 , C07D471/04 , C07D491/10 , C07D513/04
摘要: A heterocyclic derivative represented by formula (I), or a pharmaceutically acceptable salt or a stereoisomer thereof, which has an inhibitory effect on the activation of STAT3 protein, and is useful for the prevention or treatment of diseases associated with the activation of STAT3 protein.
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公开(公告)号:EP2266989A2
公开(公告)日:2010-12-29
申请号:EP09754921.6
申请日:2009-03-31
发明人: AHN, Sung Oh , PARK, Chan Hee , IM, Jun Hwan , LEE, Soon Ok , LEE, Kyoung June , CHO, Seong Wook , KO, Kwang Seok , HAN, Sun Young , LEE, Won Il
IPC分类号: C07D498/04
CPC分类号: C07D498/04
摘要: The present invention relates to heterocyclic derivatives, and more particularly, to novel heterocyclic derivatives useful for the preparation of medicaments for treating diseases related to uric acid.
摘要翻译: 本发明涉及杂环衍生物,更具体地说,涉及可用于制备用于治疗与尿酸相关疾病的药物的新型杂环衍生物。
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公开(公告)号:EP3807282A1
公开(公告)日:2021-04-21
申请号:EP19810281.6
申请日:2019-05-31
发明人: KO, Kwang Seok , LEE, Soon Ok , KWON, Young Jin , YUN, Jee Hun , CHO, Nam Chul , LEE, Ji Eun , KIM, Jung Sook
IPC分类号: C07D487/14 , A61K31/4985 , A61P29/00 , A61P37/00 , A61P11/00
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公开(公告)号:EP3227271A2
公开(公告)日:2017-10-11
申请号:EP15865425.1
申请日:2015-11-30
发明人: PARK, Chan Hee , LEE, Sang Hwi , IM, Junhwan , LEE, Soon Ok , KIM, Jungsook , PARK, Heon Kyu , YUN, Jee Hun , KO, Kwang Seok , KIM, Hye Jung , KIM, Byungho , KIM, Mi Sun , KONG, Minjung , MOON, Hyung Jo
IPC分类号: C07D333/52 , C07D495/04 , A61K31/381 , A61P35/00
CPC分类号: C07D495/04 , C07D209/42 , C07D333/70 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/06 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , C07D487/10 , C07D498/04
摘要: A heterocyclic derivative represented by formula (I), or a pharmaceutically acceptable salt or a stereoisomer thereof, which has an inhibitory effect on the activation of STAT3 protein, and is useful for the prevention or treatment of diseases associated with the activation of STAT3 protein.
摘要翻译: 由式(I)表示的杂环衍生物或其药学上可接受的盐或立体异构体,其对STAT3蛋白质的活化具有抑制作用,并且可用于预防或治疗与STAT3蛋白质的活化有关的疾病。
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公开(公告)号:EP3802495A1
公开(公告)日:2021-04-14
申请号:EP19812552.8
申请日:2019-05-31
发明人: PARK, Chan Hee , IM, Jun Hwan , LEE, Soon Ok , LEE, Sang Hwi , KO, Kwang Seok , KIM, Byung Ho , MOON, Hyung Jo , KIM, Jae Ill , PARK, Heon Kyu , HONG, Yeon Ju
IPC分类号: C07D215/38 , A61K31/47 , A61K31/502 , A61K31/517 , A61K31/53 , A61P35/00 , A61P37/00 , A61P31/06
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公开(公告)号:EP3004057B1
公开(公告)日:2018-07-25
申请号:EP14806807.5
申请日:2014-06-03
发明人: PARK, Chan Hee , LEE, Sang Hwi , IM, Junhwan , LEE, Soon Ok , KIM, Hoe Moon , MOON, Sung Hyun , KIM, Seunghee , KIM, Jongmin , KO, Kwang Seok , CHOI, Bu Young , KIM, Byungho
IPC分类号: C07D209/42 , A61K31/404 , A61P35/00 , A61P29/00
CPC分类号: C07D495/04 , C07D209/42 , C07D277/68 , C07D307/86 , C07D333/68 , C07D333/70 , C07D401/12 , C07D403/12 , C07D409/12 , C07D413/12 , C07D417/04 , C07D471/04 , C07D491/10 , C07D513/04
摘要: A heterocyclic derivative represented by formula (I), or a pharmaceutically acceptable salt or a stereoisomer thereof, which has an inhibitory effect on the activation of STAT3 protein, and is useful for the prevention or treatment of diseases associated with the activation of STAT3 protein.
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公开(公告)号:EP3227270A2
公开(公告)日:2017-10-11
申请号:EP15864809.7
申请日:2015-11-30
发明人: PARK, Chan Hee , LEE, Sang Hwi , IM, Junhwan , LEE, Soon Ok , KIM, Jongmin , KO, Kwang Seok , KIM, Byungho , KONG, Minjung , KIM, Mi Sun , MOON, Hyung Jo
IPC分类号: C07D333/52 , C07D495/04 , A61K31/381 , A61P35/00
CPC分类号: C07D495/04 , C07D209/42 , C07D333/70 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/06 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , C07D487/10 , C07D498/04
摘要: A heterocyclic derivative represented by formula (I), or a pharmaceutically acceptable salt or a stereoisomer thereof, which has an inhibitory effect on the activation of STAT3 protein, and is useful for the prevention or treatment of diseases associated with the activation of STAT3 protein.
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