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公开(公告)号：EP3878891A1
公开(公告)日：2021-09-15
申请号：EP20162062.2
申请日：2020-03-10
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS- , INSERM (Institut National de la Santé et de la Recherche Médicale) , Université de Nantes
摘要： The present invention provides crosslinking pairs of hydrogel precursor polymers, dynamic covalent hydrogels prepared from such crosslinking pairs of hydrogel precursors, pharmaceutical compositions comprising such precursors or hydrogels and uses thereof in a variety of applications.
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公开(公告)号：EP3373993A1
公开(公告)日：2018-09-19
申请号：EP16794314.1
申请日：2016-11-10
申请人： Ecole Nationale Veterinaire , Chu Nantes , Université de Nantes , INSERM (Institut National de la Santé et de la Recherche Médicale)
发明人： BACH, Jean-Marie , MOSSER, Mathilde , SALAMA, Apolline , MOURE, Anne , LEVEQUE, Xavier , WEISS, Pierre , GUICHEUX, Jérôme , BOYER, Cécile , RIOCHET, David
CPC分类号： A61K35/39 , A61K9/0019 , A61K9/0024 , A61K9/1652 , A61K9/5047 , A61K47/38 , A61P3/10 , C12N5/0676 , C12N5/0677 , C12N2533/30
摘要： The present invention relates to the use of insulin-producing cells encapsulated in silanized hydroxypropyl methylcellulose (Si-HPMC) for the treatment of type 1 diabetes. Methods and kits are also provided for restoring and/or maintaining euglycemia in type 1 diabetic patients and in type 1 prediabetic patients.
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3.发明公开SI-HPMC-ENCAPSULATED INSULIN-PRODUCING CELLS FOR THE TREATMENT OF TYPE 1 DIABETES 审中-公开用于治疗1型糖尿病的SI-HPMC-包封的胰岛素生产细胞
公开(公告)号：EP3167911A1
公开(公告)日：2017-05-17
申请号：EP15193861.0
申请日：2015-11-10
申请人： ONIRIS , CHU Nantes , Université de Nantes , INSERM (Institut National de la Santé et de la Recherche Médicale)
发明人： BACH, Jean-Marie , MOSSER, Mathilde , SALAMA, Apolline , MOURE, Anne , LEVEQUE, Xavier , WEISS, Pierre , GUICHEUX, Jérôme , BOYER, Cécile , RIOCHET, David
CPC分类号： A61K35/39 , A61K9/0019 , A61K9/0024 , A61K9/1652 , A61K9/5047 , A61K47/38 , C12N5/0677 , C12N2533/30
摘要： The present invention relates to the use of insulin-producing cells encapsulated in silanized hydroxypropyl methylcellulose (Si-HPMC) for the treatment of type 1 diabetes. Methods and kits are also provided for restoring and/or maintaining euglycemia in type 1 diabetic patients and in type 1 prediabetic patients.
摘要翻译： 本发明涉及包封在硅烷化羟丙基甲基纤维素（Si-HPMC）中的胰岛素生产细胞用于治疗1型糖尿病的用途。 还提供了用于恢复和/或维持1型糖尿病患者和1型前驱糖尿病患者的血糖正常的方法和试剂盒。
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公开(公告)号：EP4118136A1
公开(公告)日：2023-01-18
申请号：EP21711222.6
申请日：2021-03-10
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