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1.发明公开EXPRESSION DE RECEPTEURS A 7 DOMAINES TRANSMEMBRANAIRES EN SYSTEME BACULOVIRUS/CELLULES D'INSECTES 有权受体与在杆状病毒/ SYSTEM 7个跨膜结构域的表达
公开(公告)号：EP1523562A1
公开(公告)日：2005-04-20
申请号：EP03750832.2
申请日：2003-07-22
发明人： DEVAUCHELLE, Gérard , DEMAILLE, Jacques , FERRAZ, Conception , MATARAZZO, Valéry , RONIN, Catherine , CERUTTI, Martine
IPC分类号： C12N15/86 , C07K14/705
CPC分类号： C07K14/705 , C12N2799/026
摘要： The invention concerns the expression in a baculovirus-insect cell system of receptors with seven transmembrane domains, in particular receptors coupled to proteins G, in particular olfactory receptors, under the transcriptional control of a promoter derived from the polyhedrin promoter by deletion of all or part of the region of said promoter extending from -1 to -12 positions relative to the initiation site of the polyhedrin translation.
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2.发明公开FRAGMENTS FAB MUTANS DE L'ANTICORPS ANTI-CD4 CHIMERE 13B8.2 ET LEURS APPLICATIONS 有权嵌合抗CD4抗体13B8.2和使用的突变体Fab片段
公开(公告)号：EP1519960A2
公开(公告)日：2005-04-06
申请号：EP03755580.2
申请日：2003-07-07
发明人： DEVAUX, Christian,361, rue du Pré aux Clercs , BES, Cédric , BRIANT-LONGUET, Laurence , CERUTTI, Martine , DEVAUCHELLE, Gérard , CHARDES, Thierry , GRANIER, Claude , PAU, Bernard
CPC分类号： C07K16/2812 , A61K2039/505 , C07K2317/55
摘要： The invention is related to the field of immunotherapy, and concerns novel ligands for the CD4 molecule, mutant Fab 13B8.2 fragments of the CD4 antibody binding the CD4 molecule and comprising a mutation of at least one residue in a position located in the variable domain VH of the heavy chain and/or in a position located in the variable domain Vλ of the light chain. The invention also concerns pharmaceutical compositions containing said ligands for treating pathologies wherein the CD4 molecule is involved.
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3.发明公开ENZYMES A ACTIVITE ALPHA-GALACTOSYLTRANSFERASE DE CELLULES D'INSECTES, ET LEURS UTILISATIONS 审中-公开酶与α-半乳糖基转移酶活性昆虫细胞及其应用
公开(公告)号：EP1092012A1
公开(公告)日：2001-04-18
申请号：EP99926565.5
申请日：1999-06-29
IPC分类号： C12N9/10 , C12N5/06 , C12P19/18 , A61K31/715 , A23L3/3562
CPC分类号： C12N9/1051 , C12N2799/026 , C12P19/18 , C12P19/26
摘要： The invention concerns the use of enzymes derived from insect cells with α-galactosyltransferase activity for implementing an enzymatic method for preparing α-galactosyl compounds, said method comprising a step which consists in transferring a galactose residue onto a specific substrate galactose terminal residue. The invention also concerns compounds obtained by said method and their uses in food and pharmaceutical compositions.
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4.发明授权EXPRESSION DE RECEPTEURS A 7 DOMAINES TRANSMEMBRANAIRES EN SYSTEME BACULOVIRUS/CELLULES D'INSECTES 有权7-TRANSMEMBRAN跨膜受体在BACULFIRUS系统/昆虫细胞中的表达
公开(公告)号：EP1523562B1
公开(公告)日：2005-10-12
申请号：EP03750832.2
申请日：2003-07-22
发明人： DEVAUCHELLE, Gérard , DEMAILLE, Jacques , FERRAZ, Conception , MATARAZZO, Valéry , RONIN, Catherine , CERUTTI, Martine
IPC分类号： C12N15/86 , C07K14/705
CPC分类号： C07K14/705 , C12N2799/026
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