VASCULARIZATION INHIBITORS
    5.
    发明公开
    VASCULARIZATION INHIBITORS 无效
    VASKULARISIERUNGSINHIBITOREN

    公开(公告)号:EP1072273A4

    公开(公告)日:2004-04-28

    申请号:EP99909307

    申请日:1999-03-23

    CPC分类号: G01N33/5011 A61K38/1793

    摘要: Remedies inhibiting neovascularization, remedies for solid cancer, remedies for diseases pathologically caused by neovascularization and tissue repairing agents containing as the active ingredient a substance capable of potentiating CXCR4. Based on a finding that vascularization is inhibited in a CXCR4 knockout mouse, it becomes possible to prepare remedies inhibiting vascularization which contains as the active ingredient a substance capable of potentiating CXCR4, remedies for solid cancer, remedies for diseases pathologically caused by neovascularization and tissue repairing agents containing as the active ingredient a substance capable of potentiating CXCR4. It also becomes possible to establish methods for treatment with the use of these remedies.

    摘要翻译: 补救措施抑制新血管形成,治疗实体癌症,治疗新生血管病理性疾病的补救措施以及含有能够增强CXCR4的物质作为活性成分的组织修复剂。 基于在CXCR4敲除小鼠中血管化被抑制的发现,可以制备抑制血管形成的治疗剂,其包含作为活性成分的能够增强CXCR4的物质,治疗实体癌的方法,治疗由新生血管形成和组织修复病理改变的疾病 包含能够增强CXCR4的物质作为活性成分的药剂。 通过使用这些补救措施也可以建立治疗方法。