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1.NOVEL 4-PHENYLAMINO-BENZALDOXIME DERIVATIVE AND USE THEREOF AS MEK INHIBITOR 审中-公开
标题翻译: 新陈代谢维生素ALS MEK-INHIBITOR的4-苯基恶唑烷酮衍生物公开(公告)号:EP1674452A1
公开(公告)日:2006-06-28
申请号:EP04773160.9
申请日:2004-09-16
发明人: ISSHIKI, Yoshiaki, c/o CHUGAI SEIYAKU K.K. , KOHCHI, Yasunori, c/o CHUGAI SEIYAKU K.K. , HATTORI, Kazuo, c/o CHUGAI SEIYAKU K.K. , SHIMMA, Nobuo, c/o CHUGAI SEIYAKU K.K. , MIWA, Masanori, c/o CHUGAI SEIYAKU K.K. , INAGAKI, Naohito, c/o CHUGAI SEIYAKU K.K. , IIKURA, Hitoshi, c/o CHUGAI SEIYAKU K.K. , MATSUBARA, Yasuaki, c/o CHUGAI SEIYAKU K.K.
IPC分类号: C07C259/10 , C07C229/58 , C07C251/48 , C07C311/04 , C07C317/18 , C07C323/12 , C07D207/08 , C07D207/26 , C07D211/46 , C07D213/30 , C07D233/34 , C07D233/64 , C07D295/08 , C07F7/18 , A61K31/166 , A61K45/00 , A61P1/00 , A61P1/16 , A61P1/18 , A61P3/10
CPC分类号: C07D207/08 , A61K31/166 , C07C259/10 , C07C311/04 , C07C317/18 , C07C323/12 , C07C2601/02 , C07D207/27 , C07D211/46 , C07D213/30 , C07D233/32 , C07D233/64 , C07D263/32 , C07D295/088 , C07D295/155 , C07F7/1856
摘要: A compound of the present invention, or a pharmaceutically acceptable salt thereof is indicated by formula (1) below:
wherein, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , Q, R 8 , and R 9 have the same meanings as R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , Q, R 8 , and R 9 in the specification.摘要翻译: 本发明化合物或其药学上可接受的盐由下式(1)表示:其中,R 1,R 2,R 3,R 4,R 5,R 6,Q,R 8和R 9 具有与说明书中的R 1,R 2,R 3,R 4,R 5,R 6,Q,R 8和R 9相同的含义。