公开(公告)号：EP1337845A4

公开(公告)日：2007-04-11

申请号：EP01988205

申请日：2001-11-15

申请人： CIPHERGEN BIOSYSTEMS INC

发明人： PAULSE CHRIS D ,  GAVIN EDWARD J ,  BRAGINSKY LEONID ,  RICH WILLIAM E ,  FUNG ERIC T

IPC分类号： G01N27/62 ,  H01J49/40 ,  C12N15/00 ,  G01N27/64 ,  G01N31/00 ,  G01R23/16 ,  G06F19/00 ,  H01J49/00 ,  H01J49/16

CPC分类号： H01J49/0036 ,  G06F19/18 ,  G06F19/24

摘要： A method that analyzes mass spectra using a digital computer is disclosed. The method includes entering into a digital computer a data set obtained from mass spectra from a plurality of samples. Each sample is, or is to be assigned to a class within a class set having two or more classes and each class is characterized by a different biological status. A classification model is then formed. The classification model discriminates between the classes in the class set.

公开(公告)号：EP1355727A4

公开(公告)日：2007-04-11

申请号：EP01993185

申请日：2001-11-15

申请人： CIPHERGEN BIOSYSTEMS INC ,  EASTERN VIRGINIA MED SCHOOL

发明人： GAVIN EDWARD J ,  BRAGINSKY LEONID ,  RICH WILLIAM E ,  FUNG ERIC T ,  WRIGHT JR GEORGE L

IPC分类号： G01N27/62 ,  H01J49/40 ,  C12N15/00 ,  G01N27/64 ,  G01N31/00 ,  G01R23/16 ,  G06F19/00 ,  H01J49/00 ,  H01J49/16

CPC分类号： H01J49/0036 ,  G06F19/18 ,  G06F19/24

摘要： A method that analyzes mass spectra using a digital computer is disclosed. The method includes entering into a digital computer a data set (27) obtained from mass spectra from a plurality of samples. Each sample is, or is to be assigned to a class within a class set having two or more classes (30) and each class is characterized by a different biological status. A classification model (54) is then formed. The classification model discriminates between classes in the class set.

公开(公告)号：EP1576183A4

公开(公告)日：2005-09-21

申请号：EP02741639

申请日：2002-02-15

申请人： CIPHERGEN BIOSYSTEMS INC

发明人： RICH WILLIAM E ,  HUTCHENS T WILLIAM

IPC分类号： G01N27/62 ,  C12N15/09 ,  C12Q1/68 ,  G01N27/447 ,  G01N27/64 ,  G01N33/50 ,  G01N33/53 ,  G01N37/00 ,  G01N33/68

CPC分类号： C12Q1/6809 ,  Y10T436/24

摘要： The present invention relates to methods for correlating gene and protein expression in a cell. The method includes the generation of biological profiles based upon mRNA expression and the identification of physio-chemical properties of polypeptides, such that gene expression and protein expression may be correlated.