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1.发明授权MUTANT STRAIN FOR PRODUCING L-ORNITHINE OR L-ARGININE, AND METHOD FOR PRODUCING SAME 有权用于生产L-鸟氨酸或L-鸟氨酸的突变株及其制备方法
公开(公告)号：EP2522720B1
公开(公告)日：2018-03-28
申请号：EP10842313.8
申请日：2010-12-29
申请人： CJ Cheiljedang Corp.
发明人： CHO, Jin-Man , KIM, Hye-Won , LEE, Ji-Hye , CHO, Jae-Yong
CPC分类号： C12P13/10 , C12N9/1029 , C12N9/80 , C12Y203/01001 , C12Y305/01016
摘要： The present invention relates to a polynucleotide that is active to an acetyl glutamate synthase and acetyl ornithinase which are associated with ornithine or arginine biosynthesis from Corynebacterium glutamicum. The present invention also relates to a polypeptide encoded by said polynucleotide, a recombinant vector comprising said polynucleotide, to a transformant obtained by introducing said recombinant vector to a host microorganism for producing L-ornithine or L-arginine, and transforming the recombinant vector, and to a method for producing L-ornithine or L-arginine by culturing said transformant. The activity of the transformant of the present invention to an acetyl glutamate synthase and acetyl ornithinase is increased as compared to an intrinsic activity, and thus L-ornithine or L-arginine can be produced, at a high yield rate, from the transformant of the present invention.
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2.发明公开MUTANT STRAIN FOR PRODUCING L-ORNITHINE OR L-ARGININE, AND METHOD FOR PRODUCING SAME 有权生产L-鸟氨酸，L-精氨酸，及其制造方法突变株
公开(公告)号：EP2522720A2
公开(公告)日：2012-11-14
申请号：EP10842313.8
申请日：2010-12-29
申请人： CJ Cheiljedang Corp.
发明人： CHO, Jin-Man , KIM, Hye-Won , LEE, Ji-Hye , CHO, Jae-Yong
CPC分类号： C12P13/10 , C12N9/1029 , C12N9/80 , C12Y203/01001 , C12Y305/01016
摘要： The present invention relates to a polynucleotide that is active to an acetyl glutamate synthase and acetyl ornithinase which are associated with ornithine or arginine biosynthesis from Corynebacterium glutamicum. The present invention also relates to a polypeptide encoded by said polynucleotide, a recombinant vector comprising said polynucleotide, to a transformant obtained by introducing said recombinant vector to a host microorganism for producing L-ornithine or L-arginine, and transforming the recombinant vector, and to a method for producing L-ornithine or L-arginine by culturing said transformant. The activity of the transformant of the present invention to an acetyl glutamate synthase and acetyl ornithinase is increased as compared to an intrinsic activity, and thus L-ornithine or L-arginine can be produced, at a high yield rate, from the transformant of the present invention.
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