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公开(公告)号：EP4060031A1
公开(公告)日：2022-09-21
申请号：EP21870489.8
申请日：2021-04-02
发明人： PARK, Goun , KIM, Byeong Soo , LEE, Han Hyoung , BAE, Hyun Won , BYUN, Hyo Jeong , HUH, Lan , YOO, Hyeryun , KIM, Bina , SON, Sung Kwang
摘要： The present disclosure relates to a novel DAHP synthase (3-deoxy-D-arabinoheptulosonate-7-phosphate synthase) variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
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2.发明公开
公开(公告)号：EP4056583A1
公开(公告)日：2022-09-14
申请号：EP21870495.5
申请日：2021-04-02
发明人： PARK, Goun , KIM, Byeong Soo , LEE, Han Hyoung , BAE, Hyun Won , BYUN, Hyo Jeong , HUH, Lan , YOO, Hyeryun , KIM, Bina , SON, Sung Kwang
摘要： The present disclosure relates to a novel Co/Zn/Cd efflux system component variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
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公开(公告)号：EP4060029A1
公开(公告)日：2022-09-21
申请号：EP21737531.0
申请日：2021-04-01
发明人： PARK, Goun , BAE, Jee Yeon , LEE, Han Hyoung , BAE, Hyun Won , KIM, Hyo Jin , SHIN, Yong Uk
IPC分类号： C12N9/02 , C07K14/435 , C12N1/20 , C12P13/08
摘要： The present disclosure relates to a novel protein variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
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4.发明公开
公开(公告)号：EP4050023A1
公开(公告)日：2022-08-31
申请号：EP21870497.1
申请日：2021-03-31
发明人： BAE, Jee Yeon , LEE, Han Hyoung , BAE, Hyun Won , PARK, Goun , KIM, Hyo Jin , SHIN, Yong Uk
摘要： The present disclosure relates to a novel ABC transporter ATP-binding protein variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
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5.发明公开PYRUVATE DEHYDROGENASE MUTANT, MICROORGANISM COMPRISING MUTANT, AND METHOD FOR PRODUCING L-AMINO ACID BY USING MICROORGANISM 审中-公开磷酸脱氢酶突变体，包含突变体的微生物，以及使用微生物生产L-氨基酸的方法
公开(公告)号：EP3272860A1
公开(公告)日：2018-01-24
申请号：EP16765246.0
申请日：2016-03-15
发明人： HUH, Lan , MOON, Jun Ok , BAE, Hyun Won , KIM, Hyung Joon , SONG, Sung Ki
CPC分类号： C12N9/0008 , C12N15/77 , C12P13/04 , C12P13/08 , C12Y102/04001
摘要： The present disclosure relates to a novel pyruvate dehydrogenase variant, a polynucleotide encoding the pyruvate dehydrogenase variant, a microorganism of the genus Corynebacterium producing L -amino acid, which includes the pyruvate dehydrogenase variant, and a method for producing an L -amino acid using the microorganism.
摘要翻译： 本公开涉及新型丙酮酸脱氢酶变体，编码丙酮酸脱氢酶变体的多核苷酸，产生棒状杆菌的L-微生物菌属的微生物，其包含丙酮酸脱氢酶变体，以及使用该方法产生L-氨基酸的方法 微生物。
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公开(公告)号：EP4056691A1
公开(公告)日：2022-09-14
申请号：EP21870486.4
申请日：2021-04-01
发明人： PARK, Goun , BAE, Jee Yeon , LEE, Han Hyoung , BAE, Hyun Won , KIM, Hyo Jin , SHIN, Yong Uk
摘要： The present disclosure relates to a novel malate dehydrogenase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
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公开(公告)号：EP2694638B1
公开(公告)日：2018-07-18
申请号：EP12764461.5
申请日：2012-04-02
发明人： BAE, Hyun Won , KIM, Hyung Joon , MOON, Jun Ok , JANG, Jae Woo , KIM, Jong Chul , KIM, Tae Han , SUNG, Jin Suck , LEE, Kyung Han , KIM, Dae Cheol , KIM, Hyo Jin , BAE, Hyun Ae , LIM, Sang Jo
CPC分类号： C12P13/14 , C12N9/1205 , C12P13/04 , C12P13/08 , C12Y207/01004
摘要： The present invention relates to Corynebacterium sp. that is transformed with an Escherichia sp.-derived fructokinase gene to express fructokinase showing a sufficient activity of converting fructose into fructose-6-phosphate, thereby preventing unnecessary energy consumption, and a method for producing L-amino acids using the strain. The transformed Corynebacterium sp. of the present invention is able to express fructokinase from the Escherichia-derived fructokinase gene to prevent unnecessary energy consumption during fructose metabolism, leading to more cost-effective production of L-amino acids. Therefore, it can be widely used for the effective production of L-amino acids.
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8.发明公开
公开(公告)号：EP4105229A1
公开(公告)日：2022-12-21
申请号：EP21753577.2
申请日：2021-02-10
发明人： JANG, Jaewon , SHIM, Jihyun , PARK, Sang Min , BAE, Hyun Won , BYUN, Hyo Jeong , SHIN, Yong Uk , LEE, Han Hyoung , LIM, Boram , JUNG, Moo Young , CHOI, Yunjung
摘要： Provided are a microorganism comprising variant LysE, and an L-amino acid producing method using same. The variant LysE may improve L-amino acid excretion and/or production capacity compared to a wild type.
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9.发明公开
公开(公告)号：EP4083064A1
公开(公告)日：2022-11-02
申请号：EP20905486.5
申请日：2020-12-22
发明人： LEE, Han Hyoung , PARK, Sang Min , BAE, Hyun Won , BYUN, Hyo Jeong , SHIN, Yong Uk , LIM, Boram , JANG, Jaewon , JUNG, Moo Young , CHOI, Yunjung
摘要： Provided are a microorganism for producing L-amino acid, having increased cytochrome C activity, and an L-amino acid production method using the microorganism.
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10.发明公开CORYNEBACTERIUM SP. TRANSFORMED WITH A FRUCTOKINASE GENE DERIVED FROM ESCHERICHIA SP. AND PROCESS FOR PREPARING L-AMINO ACID USING THE SAME 有权棒状杆菌属WITH A大肠埃希氏SP改变。 得到果糖激酶基因和方法是这样就产生L-氨基酸
公开(公告)号：EP2694638A2
公开(公告)日：2014-02-12
申请号：EP12764461.5
申请日：2012-04-02
发明人： BAE, Hyun Won , KIM, HyungJoon , MOON, Jun Ok , JANG, Jae Woo , KIM, Jong Chul , KIM, Tae Han , SUNG, Jin Suck , LEE, Kyung Han , KIM, Dae Cheol , KIM, Hyo Jin , BAE, Hyun Ae , LIM, Sang Jo
CPC分类号： C12P13/14 , C12N9/1205 , C12P13/04 , C12P13/08 , C12Y207/01004
摘要： The present invention relates to Corynebacterium sp. that is transformed with an Escherichia sp.-derived fructokinase gene to express fructokinase showing a sufficient activity of converting fructose into fructose-6-phosphate, thereby preventing unnecessary energy consumption, and a method for producing L-amino acids using the strain. The transformed Corynebacterium sp. of the present invention is able to express fructokinase from the Escherichia-derived fructokinase gene to prevent unnecessary energy consumption during fructose metabolism, leading to more cost-effective production of L-amino acids. Therefore, it can be widely used for the effective production of L-amino acids.
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